MX2016010179A - Composiciones de donepezilo y métodos para tratar la enfermedad de alzheimer. - Google Patents
Composiciones de donepezilo y métodos para tratar la enfermedad de alzheimer.Info
- Publication number
- MX2016010179A MX2016010179A MX2016010179A MX2016010179A MX2016010179A MX 2016010179 A MX2016010179 A MX 2016010179A MX 2016010179 A MX2016010179 A MX 2016010179A MX 2016010179 A MX2016010179 A MX 2016010179A MX 2016010179 A MX2016010179 A MX 2016010179A
- Authority
- MX
- Mexico
- Prior art keywords
- donepezil
- disease
- treating alzheimer
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Se proporcionan formas farmacéuticas orales que comprenden donepezilo o una sal farmacéuticamente aceptable de este (p. ej., clorhidrato de donepezilo) solo o junto con un segundo ingrediente activo (p. ej., clorhidrato de memantina o una sal farmacéuticamente aceptable de esta) para el tratamiento de la enfermedad de Alzheimer. Las formas farmacéuticas orales comprenden gránulos de donepezilo que se pueden esparcir en la comida y pueden mejorar considerablemente la cooperación en los pacientes con dificultad de deglución.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461935596P | 2014-02-04 | 2014-02-04 | |
PCT/US2015/014404 WO2015120013A1 (en) | 2014-02-04 | 2015-02-04 | Donepezil compositions and method of treating alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016010179A true MX2016010179A (es) | 2017-04-06 |
Family
ID=53753905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016010179A MX2016010179A (es) | 2014-02-04 | 2015-02-04 | Composiciones de donepezilo y métodos para tratar la enfermedad de alzheimer. |
Country Status (7)
Country | Link |
---|---|
US (2) | US20150216849A1 (es) |
EP (1) | EP3102186B1 (es) |
JP (2) | JP6604957B2 (es) |
CA (2) | CA3214846A1 (es) |
IL (2) | IL247092B (es) |
MX (1) | MX2016010179A (es) |
WO (1) | WO2015120013A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3214846A1 (en) | 2014-02-04 | 2015-08-13 | Forest Laboratories Holdings Limited | Donepezil compositions and methods of treating alzheimer's disease |
US20180042922A1 (en) * | 2016-08-15 | 2018-02-15 | Axovant Sciences Gmbh | Compositions and methods of treating a neurodegenerative disease |
WO2018153315A1 (zh) * | 2017-02-23 | 2018-08-30 | 上海华汇拓医药科技有限公司 | 一种多奈哌齐半帕莫酸盐的粉针剂、包含其的组合物及它们的制备方法 |
WO2020068731A1 (en) * | 2018-09-25 | 2020-04-02 | The General Hospital Corporation | Methods for integrating cell gene expression data from multiple single-cell data sets and uses thereof |
WO2020208398A1 (es) * | 2019-04-09 | 2020-10-15 | Laboratorios Bagó S.A. | Composición farmacéutica en polvo con memantina y donepecilo para utilizar en el tratamiento de la enfermedad de alzheimer |
US11389458B2 (en) | 2019-04-12 | 2022-07-19 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treating parkinson's and huntington's disease |
US10639314B1 (en) | 2019-04-30 | 2020-05-05 | LA PharmaTech Inc. | Method of treating Alzheimer's disease |
US11318144B2 (en) | 2019-04-12 | 2022-05-03 | LA PharmaTech Inc. | Compositions and methods for treating Alzheimer's disease and Parkinson's disease |
US10898493B2 (en) | 2019-04-12 | 2021-01-26 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for psychiatric symptoms of patients with Alzheimer's disease |
US10966989B2 (en) * | 2019-04-12 | 2021-04-06 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treating mental, behavioral, cognitive disorders |
US11938139B2 (en) | 2019-04-12 | 2024-03-26 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for anxiety, depression and other psychiatric disorders |
US11744833B2 (en) | 2019-04-12 | 2023-09-05 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treatment of insomnia |
US11690849B2 (en) | 2019-04-12 | 2023-07-04 | LA PharmaTech Inc. | Method of treating dementia |
WO2022270663A1 (ko) * | 2021-06-23 | 2022-12-29 | 동아에스티 주식회사 | 도네페질, 실로스타졸 및 아리피프라졸을 포함하는 치매, 인지장애 또는 혈관성 우울증의 예방, 개선 또는 치료용 약학적 조성물 |
US11351179B1 (en) | 2021-08-05 | 2022-06-07 | LA PharmaTech Inc. | Pharmaceutical compositions and methods for treatment of psychiatric disorders |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES413944A1 (es) | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
DE2856393C2 (de) | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
ATE94384T1 (de) | 1989-04-14 | 1993-10-15 | Merz & Co Gmbh & Co | Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie. |
UA83645C2 (ru) | 2002-10-24 | 2008-08-11 | Мерц Фарма Гмбх Унд Ко. Кгаа | Фармацевтический продукт, который содержит производное 1-аминоциклогексана и ингибитор ацетилхолинестеразы, его применение |
CA2552221A1 (en) | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Donepezil formulations |
WO2006020853A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
RS51271B (sr) | 2004-10-19 | 2010-12-31 | Krka Tovarna Zdravil D.D. | Čvrsta farmaceutska kompozicija koja sadrži donepezil hidrohlorid |
US7619007B2 (en) * | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
US20060160852A1 (en) | 2004-12-27 | 2006-07-20 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
CA2604052C (en) * | 2005-04-06 | 2014-07-08 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of cns-related conditions |
WO2006118265A1 (ja) * | 2005-04-28 | 2006-11-09 | Eisai R & D Management Co., Ltd. | 抗痴呆薬を含有する組成物 |
US9029427B2 (en) * | 2005-11-11 | 2015-05-12 | Asahi Kasei Chemicals Corporation | Controlled release solid preparation |
GR20070100405A (el) | 2007-06-26 | 2009-01-20 | Genepharm �.�. | Βελτιωμενες φαρμακοτεχνικες μορφες που περιεχουν αναστολεις της ακετυλοχοληνεστερασης και μεθοδοι παρασκευης αυτων |
EP2211836A2 (en) | 2007-10-10 | 2010-08-04 | Rubicon Research Private Limited | Taste-masked orally disintegrating tablets of memantine hydrochloride |
US8715715B2 (en) * | 2008-11-03 | 2014-05-06 | Nal Pharmaceuticals Ltd. | Dosage form for insertion into the mouth |
TWI491395B (zh) | 2009-09-30 | 2015-07-11 | Ct Lab Inc | 一種內含用以治療神經退化性疾病之立即釋出與長效釋出藥物的口服劑量配方 |
WO2011127235A1 (en) | 2010-04-07 | 2011-10-13 | Eisai Inc. | Combination therapy for the treatment of dementia |
CN102309465B (zh) * | 2010-06-30 | 2015-04-22 | 天津药物研究院 | 含盐酸多奈哌齐活性成分的缓释片及其制备方法和用途 |
TR201007110A2 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Sinerjik etki gösteren kombinasyonlar |
EP2502620A1 (en) | 2011-03-24 | 2012-09-26 | Krka Tovarna Zdravil, D.D., Novo Mesto | Solid pharmaceutical composition comprising donepezil |
US20140243278A1 (en) * | 2011-07-05 | 2014-08-28 | Sunil Sadanand Nadkarni | Acid Addition Salt of Donepezil and Pharmaceutical Composition Thereof |
CA3214846A1 (en) | 2014-02-04 | 2015-08-13 | Forest Laboratories Holdings Limited | Donepezil compositions and methods of treating alzheimer's disease |
-
2015
- 2015-02-04 CA CA3214846A patent/CA3214846A1/en active Pending
- 2015-02-04 CA CA2938671A patent/CA2938671A1/en active Pending
- 2015-02-04 MX MX2016010179A patent/MX2016010179A/es unknown
- 2015-02-04 WO PCT/US2015/014404 patent/WO2015120013A1/en active Application Filing
- 2015-02-04 JP JP2016549781A patent/JP6604957B2/ja active Active
- 2015-02-04 EP EP15746248.2A patent/EP3102186B1/en not_active Revoked
- 2015-02-04 US US14/613,690 patent/US20150216849A1/en not_active Abandoned
-
2016
- 2016-08-03 IL IL247092A patent/IL247092B/en active IP Right Grant
-
2017
- 2017-05-15 US US15/595,101 patent/US20180169082A1/en not_active Abandoned
-
2019
- 2019-10-15 JP JP2019188336A patent/JP2020037556A/ja active Pending
-
2020
- 2020-07-27 IL IL276315A patent/IL276315A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL247092B (en) | 2020-08-31 |
CA2938671A1 (en) | 2015-08-13 |
JP6604957B2 (ja) | 2019-11-13 |
US20180169082A1 (en) | 2018-06-21 |
EP3102186B1 (en) | 2021-01-27 |
EP3102186A4 (en) | 2017-06-28 |
WO2015120013A1 (en) | 2015-08-13 |
JP2017506624A (ja) | 2017-03-09 |
IL247092A0 (en) | 2016-09-29 |
IL276315A (en) | 2020-09-30 |
US20150216849A1 (en) | 2015-08-06 |
JP2020037556A (ja) | 2020-03-12 |
CA3214846A1 (en) | 2015-08-13 |
EP3102186A1 (en) | 2016-12-14 |
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