MX2016008559A - Composiciones de matriz polimerica que comprenden una alta concentracion de hialuronato de sodio bio-fermentado y usos de las mismas. - Google Patents
Composiciones de matriz polimerica que comprenden una alta concentracion de hialuronato de sodio bio-fermentado y usos de las mismas.Info
- Publication number
- MX2016008559A MX2016008559A MX2016008559A MX2016008559A MX2016008559A MX 2016008559 A MX2016008559 A MX 2016008559A MX 2016008559 A MX2016008559 A MX 2016008559A MX 2016008559 A MX2016008559 A MX 2016008559A MX 2016008559 A MX2016008559 A MX 2016008559A
- Authority
- MX
- Mexico
- Prior art keywords
- polymer matrix
- matrix compositions
- sodium hyaluronate
- bio
- high concentration
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 229920000642 polymer Polymers 0.000 title abstract 5
- 229920002385 Sodium hyaluronate Polymers 0.000 title abstract 2
- 229940010747 sodium hyaluronate Drugs 0.000 title abstract 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 241000120569 Streptococcus equi subsp. zooepidemicus Species 0.000 abstract 1
- 206010047791 Vulvovaginal dryness Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229920000831 ionic polymer Polymers 0.000 abstract 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract 1
- 229960002216 methylparaben Drugs 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
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- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
- C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gynecology & Obstetrics (AREA)
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- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Wood Science & Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers & Plastics (AREA)
Abstract
La presente invención se refiere a composiciones de matriz polimérica estables que comprenden concentraciones elevadas (de aproximadamente 1.5% p/p a aproximadamente 3.5% p/p) de hialuronato de sodio obtenido de una fuente de Streptococcus zooepidemicus y un polímero no iónico. La composición de matriz polimérica comprende además polietilenglicol y metilparabeno, y utiliza ingredientes que son de grado farmacéutico o farmacopeico. Las composiciones de matriz polimérica pueden comprender opcionalmente un ingrediente activo. Las presentes composiciones de matriz polimérica se pueden usar en el tratamiento de heridas, quemaduras, ciertas condiciones dermatológicas, sequedad vaginal, y en la administración tópica y transdérmica y la liberación sostenida de ingredientes activos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2896038A CA2896038C (en) | 2015-07-03 | 2015-07-03 | Polymer matrix compositions comprising a high concentration of bio-fermented sodium hyaluronate and uses thereof |
EP15178106.9A EP3111925A1 (en) | 2015-07-03 | 2015-07-23 | Polymer matrix compositions comprising a high concentration of bio-fermented sodium hyaluronate and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2016008559A true MX2016008559A (es) | 2017-04-25 |
MX360365B MX360365B (es) | 2018-10-30 |
Family
ID=54064127
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016008559A MX360365B (es) | 2015-07-03 | 2016-06-27 | Composiciones de matriz polimerica que comprenden una alta concentracion de hialuronato de sodio bio-fermentado y usos de las mismas. |
Country Status (12)
Country | Link |
---|---|
US (2) | US9821005B2 (es) |
EP (1) | EP3111925A1 (es) |
KR (3) | KR20230050475A (es) |
CN (2) | CN115025114A (es) |
AR (1) | AR107212A1 (es) |
AU (1) | AU2016289095B2 (es) |
CA (1) | CA2896038C (es) |
CR (1) | CR20180014A (es) |
EC (1) | ECSP17081071A (es) |
MX (1) | MX360365B (es) |
SA (1) | SA517390331B1 (es) |
WO (1) | WO2017004706A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113045773B (zh) * | 2021-03-16 | 2022-05-31 | 南京林业大学 | 一种在兽疫链球菌发酵过程中原位诱导纳米纤维素凝胶化的方法 |
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JPS60251898A (ja) * | 1984-05-25 | 1985-12-12 | Shiseido Co Ltd | 醗酵法によるヒアルロン酸の製造方法 |
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KR100927579B1 (ko) * | 2006-12-13 | 2009-11-23 | 주식회사 엘지생명과학 | 히아루론산 및/또는 그것의 염을 함유하는 아토피성피부염의 개선 및 치료를 위한 조성물 |
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CN103254118A (zh) | 2012-02-17 | 2013-08-21 | 温州大学 | 一种Hg2+探针的制备方法 |
EP2854786B1 (en) * | 2012-06-05 | 2017-03-29 | Olatec Therapeutics LLC | Pharmaceutical composition for treating inflammation and pain |
AU2014252652A1 (en) * | 2013-04-10 | 2015-11-26 | Glycobiosciences, Inc. | Topical nutraceutical composition |
CN103254448B (zh) * | 2013-05-17 | 2015-06-24 | 成都金凯生物技术有限公司 | 一种医用透明质酸钠凝胶及其制备方法 |
CN103405470B (zh) * | 2013-08-22 | 2016-08-10 | 北京泰克美高新技术有限公司 | 透明质酸和透明质酸盐在用于治疗和缓解口腔干燥的组合物的应用 |
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2015
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- 2015-07-23 EP EP15178106.9A patent/EP3111925A1/en active Pending
- 2015-08-05 US US14/818,810 patent/US9821005B2/en active Active
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2016
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- 2016-01-07 CN CN201610010139.3A patent/CN106309473A/zh active Pending
- 2016-06-27 MX MX2016008559A patent/MX360365B/es active IP Right Grant
- 2016-06-30 CR CR20180014A patent/CR20180014A/es unknown
- 2016-06-30 KR KR1020237011305A patent/KR20230050475A/ko not_active Application Discontinuation
- 2016-06-30 WO PCT/CA2016/050774 patent/WO2017004706A1/en active Application Filing
- 2016-06-30 KR KR1020217004367A patent/KR20210020171A/ko active Application Filing
- 2016-06-30 KR KR1020187002995A patent/KR20180059748A/ko not_active Application Discontinuation
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2017
- 2017-10-09 US US15/727,820 patent/US10322142B2/en active Active
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AU2016289095A1 (en) | 2017-12-07 |
US9821005B2 (en) | 2017-11-21 |
EP3111925A1 (en) | 2017-01-04 |
CA2896038A1 (en) | 2016-05-03 |
CN106309473A (zh) | 2017-01-11 |
SA517390331B1 (ar) | 2023-11-30 |
CN115025114A (zh) | 2022-09-09 |
AU2016289095B2 (en) | 2017-12-14 |
WO2017004706A1 (en) | 2017-01-12 |
CA2896038C (en) | 2022-08-09 |
US20180042957A1 (en) | 2018-02-15 |
KR20210020171A (ko) | 2021-02-23 |
KR20180059748A (ko) | 2018-06-05 |
US10322142B2 (en) | 2019-06-18 |
AR107212A1 (es) | 2018-04-11 |
MX360365B (es) | 2018-10-30 |
CR20180014A (es) | 2018-05-29 |
ECSP17081071A (es) | 2018-04-30 |
KR20230050475A (ko) | 2023-04-14 |
US20170020912A1 (en) | 2017-01-26 |
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