MX2016005657A - Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. - Google Patents
Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas.Info
- Publication number
- MX2016005657A MX2016005657A MX2016005657A MX2016005657A MX2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A MX 2016005657 A MX2016005657 A MX 2016005657A
- Authority
- MX
- Mexico
- Prior art keywords
- cells
- differentiation
- clustering
- suspension
- pluripotent stem
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 title abstract 3
- 210000003890 endocrine cell Anatomy 0.000 title abstract 2
- 230000009996 pancreatic endocrine effect Effects 0.000 title abstract 2
- 210000001778 pluripotent stem cell Anatomy 0.000 title abstract 2
- 239000000725 suspension Substances 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 abstract 1
- 210000001705 ectoderm cell Anatomy 0.000 abstract 1
- 210000001900 endoderm Anatomy 0.000 abstract 1
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 210000001704 mesoblast Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361962158P | 2013-11-01 | 2013-11-01 | |
US13/998,974 US10377989B2 (en) | 2012-12-31 | 2013-12-30 | Methods for suspension cultures of human pluripotent stem cells |
PCT/US2014/038993 WO2015065524A2 (en) | 2013-11-01 | 2014-05-21 | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016005657A true MX2016005657A (es) | 2017-01-05 |
Family
ID=53004904
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016005657A MX2016005657A (es) | 2013-11-01 | 2014-05-21 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
MX2016005658A MX2016005658A (es) | 2013-11-01 | 2014-06-17 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016005658A MX2016005658A (es) | 2013-11-01 | 2014-06-17 | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP3063268A4 (ko) |
JP (2) | JP2016534731A (ko) |
KR (4) | KR20160079072A (ko) |
CN (2) | CN105793413A (ko) |
AU (4) | AU2014342995C1 (ko) |
BR (1) | BR112016009393A8 (ko) |
CA (2) | CA2928639A1 (ko) |
MX (2) | MX2016005657A (ko) |
PH (2) | PH12016500782A1 (ko) |
RU (2) | RU2689710C2 (ko) |
SG (2) | SG11201603045VA (ko) |
WO (2) | WO2015065524A2 (ko) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016534731A (ja) * | 2013-11-01 | 2016-11-10 | ヤンセン バイオテツク,インコーポレーテツド | 膵内分泌細胞への分化のためのヒト多能性幹細胞の懸濁及び集団化 |
EP3474866A4 (en) * | 2016-06-23 | 2020-02-26 | Tithon Biotech, Inc. | CELLS EXPRESSING THE PARATHYROID HORMONE RECEPTOR 1 AND USES THEREOF |
JP7024978B2 (ja) * | 2016-11-16 | 2022-03-03 | サイナータ セラピューティクス リミテッド | 多能性幹細胞のアッセイ |
US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
CA3070596A1 (en) * | 2017-07-21 | 2019-01-24 | Semma Therapeutics, Inc. | Re-aggregation of stem cell-derived pancreatic beta cells |
JP7000896B2 (ja) * | 2017-08-23 | 2022-01-19 | 王子ホールディングス株式会社 | 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法 |
CA3087344A1 (en) * | 2018-01-05 | 2019-07-11 | Platelet Biogenesis, Inc. | Compositions and methods for producing megakaryocytes |
JP2021510527A (ja) * | 2018-01-18 | 2021-04-30 | エージェンシー フォー サイエンス, テクノロジー アンド リサーチ | 懸濁培養におけるヒト多能性幹細胞系の分化のための方法 |
KR102115360B1 (ko) * | 2018-05-30 | 2020-05-26 | 주식회사 바이블리오테카 | 성체 줄기세포 배양액 및 그 제조방법 |
US10724052B2 (en) | 2018-09-07 | 2020-07-28 | Crispr Therapeutics Ag | Universal donor cells |
US20220234006A1 (en) | 2019-05-31 | 2022-07-28 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
US20220233298A1 (en) | 2019-05-31 | 2022-07-28 | W. L. Gore & Associates, Inc. | A biocompatible membrane composite |
EP3975925A1 (en) | 2019-05-31 | 2022-04-06 | W.L. Gore & Associates, Inc. | A biocompatible membrane composite |
EP3976237A1 (en) | 2019-05-31 | 2022-04-06 | W.L. Gore & Associates Inc. | Cell encapsulation devices with controlled oxygen diffusion distances |
US11104918B2 (en) | 2019-09-05 | 2021-08-31 | Crispr Therapeutics Ag | Universal donor cells |
WO2021044377A1 (en) | 2019-09-05 | 2021-03-11 | Crispr Therapeutics Ag | Universal donor cells |
CN114729323A (zh) * | 2019-11-22 | 2022-07-08 | 诺和诺德股份有限公司 | 旋转聚集的神经微球及其应用 |
JP2024503291A (ja) | 2020-12-31 | 2024-01-25 | クリスパー セラピューティクス アクチェンゲゼルシャフト | ユニバーサルドナー細胞 |
US20240191185A1 (en) * | 2021-03-25 | 2024-06-13 | Kaneka Corporation | Method for producing pluripotent stem cell population |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
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MXPA04004311A (es) * | 2001-11-09 | 2005-03-31 | Artecel Sciences Inc | DIFERENCIACION DEL PáNCREAS ENDOCRINOS DE CELULAS ESTROMALES DERIVADAS DEL TEJIDO ADIPOSO Y USOS DE LAS MISMAS. |
DK2733203T3 (en) * | 2006-08-02 | 2019-02-04 | Technion Res & Dev Foundation | PROCEDURES FOR EXPANSION OF EMBRYONAL STEM CELLS IN A SUSPENSION CULTURE |
EP2088190A4 (en) * | 2006-11-09 | 2011-01-05 | Japan Government | METHOD FOR THE CULTURE AND PASSAGE OF PRIMATE EMBRYONIC STRAIN CELL, AND METHOD FOR INDUCING DIFFERENTIATION OF EMBRYONIC STEM CELL |
US20090053182A1 (en) * | 2007-05-25 | 2009-02-26 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
EP3192865B1 (en) * | 2007-07-01 | 2021-04-21 | Janssen Biotech, Inc. | Single pluripotent stem cell culture |
GB0800524D0 (en) * | 2008-01-14 | 2008-02-20 | Univ Brighton | Cell culture system |
EP2479260B1 (en) * | 2008-03-17 | 2016-01-06 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
CN102159703B (zh) * | 2008-06-30 | 2015-11-25 | 森托科尔奥索生物科技公司 | 多能干细胞的分化 |
US8008075B2 (en) * | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
US8895300B2 (en) * | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
US10119120B2 (en) * | 2009-08-12 | 2018-11-06 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into neural precursor cells |
JP5936134B2 (ja) * | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
US9085757B2 (en) * | 2010-06-17 | 2015-07-21 | Regents Of The University Of Minnesota | Production of insulin producing cells |
SG10201506852VA (en) * | 2010-08-31 | 2015-10-29 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
MY177150A (en) * | 2011-02-28 | 2020-09-08 | Stempeutics Res Malaysia Sdn Bhd | Isolation and expansion of adult stem cells, their therapeutic composition and uses thereof |
US8951798B2 (en) * | 2011-10-13 | 2015-02-10 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
CN105143446B (zh) * | 2011-12-22 | 2020-11-03 | 詹森生物科技公司 | 人胚胎干细胞分化成单一激素胰岛素阳性细胞 |
US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
CN105705634A (zh) * | 2012-12-31 | 2016-06-22 | 詹森生物科技公司 | 用于分化成胰腺内分泌细胞的人多能细胞的悬浮和群集 |
JP2016534731A (ja) * | 2013-11-01 | 2016-11-10 | ヤンセン バイオテツク,インコーポレーテツド | 膵内分泌細胞への分化のためのヒト多能性幹細胞の懸濁及び集団化 |
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2014
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- 2014-05-21 KR KR1020167014409A patent/KR20160079072A/ko active Application Filing
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- 2014-05-21 MX MX2016005657A patent/MX2016005657A/es unknown
- 2014-05-21 EP EP14857034.4A patent/EP3063268A4/en not_active Withdrawn
- 2014-05-21 AU AU2014342995A patent/AU2014342995C1/en not_active Ceased
- 2014-05-21 CA CA2928639A patent/CA2928639A1/en not_active Abandoned
- 2014-05-21 RU RU2016121409A patent/RU2689710C2/ru active
- 2014-05-21 SG SG11201603045VA patent/SG11201603045VA/en unknown
- 2014-05-21 KR KR1020187034291A patent/KR20180128529A/ko active IP Right Grant
- 2014-05-21 WO PCT/US2014/038993 patent/WO2015065524A2/en active Application Filing
- 2014-06-17 AU AU2014343007A patent/AU2014343007C1/en not_active Ceased
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