MX2016003046A - Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. - Google Patents
Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos.Info
- Publication number
- MX2016003046A MX2016003046A MX2016003046A MX2016003046A MX2016003046A MX 2016003046 A MX2016003046 A MX 2016003046A MX 2016003046 A MX2016003046 A MX 2016003046A MX 2016003046 A MX2016003046 A MX 2016003046A MX 2016003046 A MX2016003046 A MX 2016003046A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- making
- same
- microbial infection
- antimicrobial compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
En el presente se divulgan métodos y compuestos para tratar, prevenir, reducir el riesgo de, y/o retrasar la aparición de una infección microbiana en un sujeto, en donde la infección microbiana es causada por uno o más microorganismos (por ejemplo, una o más bacterias) que pueden utilizarse como arma biológica, tales como Bacillus anthracis, Franciscella tularensis, Yersina pestis, Burkholderia mallei, y Burkholderia pseudomallei. También se divulgan composiciones farmacéuticas o kits para tratar, prevenir, reducir el riesgo de y/o retrasar la aparición de una infección microbiana.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361875642P | 2013-09-09 | 2013-09-09 | |
PCT/US2014/054860 WO2015035421A1 (en) | 2013-09-09 | 2014-09-09 | Antimicrobial compounds and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016003046A true MX2016003046A (es) | 2016-09-08 |
Family
ID=52629043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016003046A MX2016003046A (es) | 2013-09-09 | 2014-09-09 | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. |
Country Status (7)
Country | Link |
---|---|
US (1) | US9937183B2 (es) |
EP (1) | EP3038623A4 (es) |
JP (1) | JP2016529325A (es) |
AU (1) | AU2014315045A1 (es) |
CA (1) | CA2923179A1 (es) |
MX (1) | MX2016003046A (es) |
WO (1) | WO2015035421A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102725274A (zh) | 2009-10-16 | 2012-10-10 | Rib-X制药公司 | 抗微生物化合物和其制备和使用方法 |
MX359743B (es) | 2009-10-16 | 2018-10-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos para fabricar y utilizar los mismos. |
MX2016003046A (es) | 2013-09-09 | 2016-09-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. |
KR20160070066A (ko) * | 2013-09-09 | 2016-06-17 | 멜린타 테라퓨틱스, 인크. | 항균 화합물, 및 이의 제조 방법 및 이용 방법 |
BR112017019349A2 (pt) * | 2015-03-11 | 2018-06-05 | Melinta Therapeutics Inc | compostos antimicrobianos e métodos de fabricação e uso dos mesmos |
WO2017193023A1 (en) * | 2016-05-06 | 2017-11-09 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
CN110312722A (zh) | 2016-05-06 | 2019-10-08 | 生物验证系统股份公司 | 抗微生物剂及其制备和使用方法 |
US11122800B2 (en) * | 2017-10-30 | 2021-09-21 | Troy Corporation | Antimicrobial organic preservatives |
US20210253577A1 (en) | 2018-06-06 | 2021-08-19 | BioVersys AG | Biodefense agents |
WO2020115547A2 (en) * | 2018-12-07 | 2020-06-11 | BioVersys AG | Pyrrolo[2,3-d]pyrimidin-2-one antimicrobial compounds |
JP2023501575A (ja) * | 2019-11-13 | 2023-01-18 | カーザ グローバル, エルエルシー | 抗菌化合物及び方法 |
Family Cites Families (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2624731A (en) | 1953-01-06 | S-phenylpyrimidkn e x derivativesx | ||
US3980781A (en) | 1966-03-31 | 1976-09-14 | Imperial Chemical Industries Limited | Fungicidal composition and method containing 2-amino-pyrimidines |
US4361557A (en) | 1980-01-28 | 1982-11-30 | Schering Corporation | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor |
EP0067610A1 (en) | 1981-06-16 | 1982-12-22 | Beecham Group Plc | Penicillins, a process for their preparation and compositions containing them |
US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
US5332835A (en) | 1984-02-03 | 1994-07-26 | Zambon S.P.A. | Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process |
JPS6191184A (ja) | 1984-10-08 | 1986-05-09 | Morishita Seiyaku Kk | 2−アニリノ−5−(1h−テトラゾ−ル−5−イル)ピリミジン−4(3h)−オン誘導体 |
JP2873340B2 (ja) | 1988-04-29 | 1999-03-24 | 武田薬品工業株式会社 | 抗生物質tan―1057,その製造法および用途 |
JP2991382B2 (ja) | 1990-07-18 | 1999-12-20 | 大日本製薬株式会社 | 縮合三環式化合物およびその塩 |
US5208141A (en) | 1990-10-09 | 1993-05-04 | Konica Corporation | Silver halide color photographic light-sensitive material |
US5958930A (en) | 1991-04-08 | 1999-09-28 | Duquesne University Of The Holy Ghost | Pyrrolo pyrimidine and furo pyrimidine derivatives |
US6451968B1 (en) | 1991-05-24 | 2002-09-17 | Isis Pharmaceuticals, Inc. | Peptide nucleic acids |
US5434257A (en) | 1992-06-01 | 1995-07-18 | Gilead Sciences, Inc. | Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages |
US5646163A (en) | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
RU2139862C1 (ru) | 1993-05-12 | 1999-10-20 | Е.И. Дю Пон де Немурс энд Компани | Замещенные 4(3н)-хиназолиноны, обладающие фунгицидными свойствами, композиции на их основе и способы борьбы с мучнистой росой |
US5502177A (en) | 1993-09-17 | 1996-03-26 | Gilead Sciences, Inc. | Pyrimidine derivatives for labeled binding partners |
US5567884A (en) | 1994-03-09 | 1996-10-22 | International Business Machines Corporation | Circuit board assembly torsion tester and method |
US5668127A (en) | 1995-06-26 | 1997-09-16 | Pathogenesis Corporation | Nitroimidazole antibacterial compounds and methods of use thereof |
TW424090B (en) | 1995-08-18 | 2001-03-01 | Nat Science Council | Pyrimidines as folate antimetabolites with selective activity against human brain cancer |
US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
US7282327B2 (en) | 1996-01-23 | 2007-10-16 | Affymetrix, Inc. | Nucleic acid labeling compounds |
GB9708611D0 (en) | 1997-04-28 | 1997-06-18 | Univ Cardiff | Chemical compounds |
US6110925A (en) | 1997-08-07 | 2000-08-29 | Research Corporation Technologies, Inc. | Antibiotic for methicillin resistant bacteria |
WO1999024452A2 (en) | 1997-11-07 | 1999-05-20 | Isis Pharmaceuticals, Inc. | Pyrimidine derivatives for labeled binding partners |
US6028183A (en) | 1997-11-07 | 2000-02-22 | Gilead Sciences, Inc. | Pyrimidine derivatives and oligonucleotides containing same |
DE19838998A1 (de) | 1998-08-27 | 2000-03-09 | Bayer Ag | Neue Naturstoffderivate |
SE9903894D0 (sv) | 1999-10-28 | 1999-10-28 | New Pharma Research Ab | Novel compounds |
EP1113008A1 (en) | 1999-12-29 | 2001-07-04 | Pfizer Products Inc. | 4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidine derivatives useful as antibacterial and antiprotozoal agents |
KR100358083B1 (ko) | 2000-02-17 | 2002-10-25 | 에스케이케미칼주식회사 | 피롤로피리미디논 유도체와 이의 제조방법, 그리고 이의용도 |
BR0114837A (pt) | 2000-10-18 | 2006-05-09 | Pharmasset Ltd | nucleosìdeos modificados para tratamento de infecções viróticas e proliferação celular anormal |
DE10061541A1 (de) | 2000-12-11 | 2002-06-20 | Bayer Ag | Arylamino-Dihydropyrimidinone |
DE10061537A1 (de) | 2000-12-11 | 2002-06-20 | Bayer Ag | beta-Alanin-Derivate |
DE10061542A1 (de) | 2000-12-11 | 2002-06-13 | Bayer Ag | Alkanoylamino-pyrimidine |
DE10061538A1 (de) | 2000-12-11 | 2002-06-20 | Bayer Ag | Ureido-Dihydropyrimidinone |
WO2002048138A1 (en) | 2000-12-14 | 2002-06-20 | The Procter & Gamble Company | Antimicrobial quinolones |
US6900215B2 (en) | 2000-12-15 | 2005-05-31 | Merck Sharp & Dohme Ltd. | Imidazo-pyrimidine derivatives as ligands for gaba receptors |
AU2002230058B2 (en) | 2001-01-29 | 2005-11-17 | Bio-Rad Laboratories, Inc. | Nucleic acid derivatives |
TWI248936B (en) | 2001-03-21 | 2006-02-11 | Merck Sharp & Dohme | Imidazo-pyrimidine derivatives as ligands for GABA receptors |
US20030207804A1 (en) | 2001-05-25 | 2003-11-06 | Muthiah Manoharan | Modified peptide nucleic acids |
US20030158403A1 (en) | 2001-07-03 | 2003-08-21 | Isis Pharmaceuticals, Inc. | Nuclease resistant chimeric oligonucleotides |
CA2452458A1 (en) | 2001-07-03 | 2003-01-16 | Isis Pharmaceuticals, Inc. | Nuclease resistant chimeric oligonucleotides |
DE10133277A1 (de) | 2001-07-09 | 2003-01-23 | Bayer Ag | ß-Alanin-Derivate |
DE10141271A1 (de) | 2001-08-23 | 2003-03-06 | Bayer Ag | Neue Tetrahydro-1,3,5-triazin-2-on-Derivate und ihre Verwendung |
DE10208256A1 (de) | 2002-02-26 | 2003-09-04 | Bayer Ag | Piperidinouracile |
BR0308289A (pt) | 2002-03-08 | 2005-01-11 | Schering Plough Ltd | Antibióticos do tipo florfenicol |
AU2003225705A1 (en) | 2003-03-07 | 2004-09-30 | Ribapharm Inc. | Cytidine analogs and methods of use |
NZ545157A (en) | 2003-08-12 | 2009-03-31 | Achillion Pharmaceuticals Inc | Isothiazoloquinolones and related compounds as anti-infective agents |
EP1661897B1 (en) | 2003-08-26 | 2013-12-04 | Teijin Pharma Limited | Pyrrolopyrimidinone derivative |
TW200524880A (en) | 2003-10-21 | 2005-08-01 | Sankyo Co | Pyrimidine compounds |
WO2007014308A1 (en) | 2005-07-27 | 2007-02-01 | Achillion Pharmaceuticals, Inc. | 8-methoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones and related compounds as anti-infective agents |
CN101360720A (zh) | 2005-11-15 | 2009-02-04 | 阿斯利康(瑞典)有限公司 | 新颖的2-氨基嘧啶酮衍生物及其用途 |
NZ544187A (en) | 2005-12-15 | 2008-07-31 | Ind Res Ltd | Deazapurine analogs of 1'-aza-l-nucleosides |
JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
DE602007012161D1 (de) | 2006-03-03 | 2011-03-10 | Fujifilm Corp | Härtbare Zusammensetzung, Tintenzusammensetzung, Tintenstrahlaufzeichnungsverfahren und Flachdruckplatte |
JP2007270087A (ja) | 2006-03-31 | 2007-10-18 | Fujifilm Corp | 硬化性組成物、インク組成物、インクジェット記録方法、印刷物、平版印刷版の製造方法、及び平版印刷版 |
KR20080003599A (ko) | 2006-07-03 | 2008-01-08 | 에스케이케미칼주식회사 | 피롤로피리미디논 유도체의 겐티세이트 염 및 이의제조방법 |
MX2009000102A (es) | 2006-07-03 | 2009-03-02 | Sk Chemicals Co Ltd | Sales de derivados de pirrolopirimidinona y proceso para prepararlas. |
US20100112561A1 (en) | 2006-08-25 | 2010-05-06 | Stefan Lutz | Fluorescent nucleoside analogues |
PL2057165T3 (pl) | 2006-09-07 | 2011-08-31 | Victoria Link Ltd | Acykliczne inhibitory aminowe fosforylaz i hydrolaz nukleozydowych |
WO2008106224A1 (en) | 2007-02-28 | 2008-09-04 | Rib-X Pharmaceuticals, Inc. | Macrolide compounds and methods of making and using the same |
EP1964841A1 (en) | 2007-02-28 | 2008-09-03 | sanofi-aventis | Imidazo[1,2-a]azine and their use as pharmaceuticals |
EP2125816A2 (en) | 2007-03-07 | 2009-12-02 | Alantos Pharmaceuticals Holding, Inc. | Metalloprotease inhibitors containing a heterocyclic moiety |
JP2008222557A (ja) | 2007-03-08 | 2008-09-25 | Kotobuki Seiyaku Kk | ピロロ[3,2−d]ピリミジン誘導体及びこれを有効成分とする医薬組成物 |
US20080319200A1 (en) | 2007-05-30 | 2008-12-25 | Schering-Plough Animal Health Corp. | Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol |
CN101765585B (zh) | 2007-06-12 | 2017-03-15 | 尔察祯有限公司 | 抗菌剂 |
GB0724342D0 (en) | 2007-12-13 | 2008-01-30 | Prolysis Ltd | Anitbacterial compositions |
KR20090098710A (ko) | 2008-03-14 | 2009-09-17 | 주식회사 씨티아이바이오 | 세포투과성과 핵산 결합력이 좋은 펩타이드 핵산 유도체 |
UY32395A (es) | 2009-01-27 | 2010-08-31 | Takeda Pharmaceutical | Compuesto con anillo fusionado y su uso |
US20120263646A1 (en) | 2009-10-15 | 2012-10-18 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
CN102725274A (zh) | 2009-10-16 | 2012-10-10 | Rib-X制药公司 | 抗微生物化合物和其制备和使用方法 |
CN104628729B (zh) | 2009-10-16 | 2018-11-06 | 梅琳塔治疗公司 | 抗微生物化合物和其制备和使用方法 |
ES2675798T3 (es) | 2009-10-16 | 2018-07-12 | Melinta Therapeutics, Inc. | Compuestos antimicrobianos y métodos para fabricar y usar los mismos |
MX359743B (es) | 2009-10-16 | 2018-10-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos para fabricar y utilizar los mismos. |
WO2012125832A2 (en) | 2011-03-15 | 2012-09-20 | Rib-X Pharmaceuticals, Inc. | Antimicrobial agents |
ES2665988T3 (es) * | 2011-04-15 | 2018-04-30 | Melinta Therapeutics, Inc. | Compuestos antimicrobianos y métodos de fabricación y uso de los mismos |
KR20160070066A (ko) | 2013-09-09 | 2016-06-17 | 멜린타 테라퓨틱스, 인크. | 항균 화합물, 및 이의 제조 방법 및 이용 방법 |
MX2016003046A (es) | 2013-09-09 | 2016-09-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. |
-
2014
- 2014-09-09 MX MX2016003046A patent/MX2016003046A/es unknown
- 2014-09-09 JP JP2016540936A patent/JP2016529325A/ja active Pending
- 2014-09-09 EP EP14841940.1A patent/EP3038623A4/en not_active Withdrawn
- 2014-09-09 WO PCT/US2014/054860 patent/WO2015035421A1/en active Application Filing
- 2014-09-09 US US14/917,920 patent/US9937183B2/en not_active Expired - Fee Related
- 2014-09-09 AU AU2014315045A patent/AU2014315045A1/en not_active Abandoned
- 2014-09-09 CA CA2923179A patent/CA2923179A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3038623A1 (en) | 2016-07-06 |
CA2923179A1 (en) | 2015-03-12 |
JP2016529325A (ja) | 2016-09-23 |
AU2014315045A1 (en) | 2016-03-24 |
US20160220568A1 (en) | 2016-08-04 |
WO2015035421A1 (en) | 2015-03-12 |
EP3038623A4 (en) | 2017-04-19 |
US9937183B2 (en) | 2018-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2016003046A (es) | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. | |
EP3409666A3 (en) | Seca inhibitors and methods of making and using thereof | |
MX2015007556A (es) | Derivados de manosa para tratar infecciones bacterianas. | |
GB2551642A (en) | Methods and compositions relating to microbial treatment and diagnosis of dis-orders | |
AU2015205914B2 (en) | 1,6- diazabicyclo [3,2,1] octan- 7- one derivatives and their use in the treatment of bacterial infections | |
GB201013307D0 (en) | Anti-microbial metal organic framework | |
BR112012018170B8 (pt) | agente antimicrobiano para redução, inibição ou tratamento do crescimento microbiano, infecções microbianas, doenças inflamatórias, doenças ou condições virais resultantes de ou associadas aos mesmos | |
NZ733174A (en) | Quinazoline derivatives used to treat hiv | |
MX2017010710A (es) | Composición terapeútica y profiláctica producida por microbiota. | |
PH12015502401A1 (en) | Compositions and methods for enhancing microbial stability | |
MX2017012545A (es) | Compuestos heterociclicos y su uso en la prevencion o tratamiento de las infecciones bacterianas. | |
MX2016009898A (es) | Tratamientos para acne resistente. | |
EA201692303A1 (ru) | Новая противоинфекционная стратегия против коинфекций, вызванных вирусом гриппа и s.aureus | |
MY179292A (en) | Monobactam organic compounds for the treatment of bacterial infections | |
WO2019067380A3 (en) | Treatment of mosaic viruses and bacterial infections of plants | |
IN2014MN02438A (es) | ||
BR112013005426A2 (pt) | "composto, composição, formulação farmacêutica, métodos para inibir uma enzima, para matar e/ou prevenir o crescimento de um micro-organismo, para tratar e/ou prevenir uma doença em um animal, e para inibir o domínio de edição de uma sintetase de t-rna, e, uso de um composto ou uma de combinação." | |
PH12017501019B1 (en) | Isoxazole hydromaxamic acid compounds as lpxc inhibitors | |
EA201692494A1 (ru) | Композиции, содержащие липохитоолигосахарид и микроорганизм для усиления роста растения | |
WO2016183532A8 (en) | Bacteria engineered to treat a disease or disorder | |
WO2015175977A3 (en) | Antisense antibacterial compounds and methods | |
MX2019005097A (es) | Composiciones y metodos para tratar la enfermedad del enverdecimiento de los citricos. | |
PH12019500360A1 (en) | Antibiotic compounds | |
WO2015100331A3 (en) | Phenazine derivatives as antimicrobial agents | |
WO2016004513A8 (en) | Anti-bacterial pyruvate kinase modulator compounds, compositions, uses and methods |