MX2015013419A - Cianoetilpirazolo piridonas aciclicas como inhibidores de janus quinasa. - Google Patents
Cianoetilpirazolo piridonas aciclicas como inhibidores de janus quinasa.Info
- Publication number
- MX2015013419A MX2015013419A MX2015013419A MX2015013419A MX2015013419A MX 2015013419 A MX2015013419 A MX 2015013419A MX 2015013419 A MX2015013419 A MX 2015013419A MX 2015013419 A MX2015013419 A MX 2015013419A MX 2015013419 A MX2015013419 A MX 2015013419A
- Authority
- MX
- Mexico
- Prior art keywords
- cyanoethylpyrazolo
- pyridones
- acyclic
- kinase inhibitors
- janus kinase
- Prior art date
Links
- 229940122245 Janus kinase inhibitor Drugs 0.000 title abstract 2
- -1 Acyclic cyanoethylpyrazolo pyridones Chemical class 0.000 title 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361803241P | 2013-03-19 | 2013-03-19 | |
| PCT/CN2014/000299 WO2014146493A1 (en) | 2013-03-19 | 2014-03-19 | Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015013419A true MX2015013419A (es) | 2016-07-19 |
Family
ID=51579322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015013419A MX2015013419A (es) | 2013-03-19 | 2014-03-19 | Cianoetilpirazolo piridonas aciclicas como inhibidores de janus quinasa. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10059705B2 (OSRAM) |
| EP (1) | EP2976341B1 (OSRAM) |
| JP (1) | JP6305510B2 (OSRAM) |
| KR (1) | KR20150132170A (OSRAM) |
| CN (1) | CN105121444B (OSRAM) |
| AU (1) | AU2014234909B2 (OSRAM) |
| BR (1) | BR112015024050A2 (OSRAM) |
| CA (1) | CA2901770A1 (OSRAM) |
| MX (1) | MX2015013419A (OSRAM) |
| RU (1) | RU2015144385A (OSRAM) |
| WO (1) | WO2014146493A1 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014146246A1 (en) | 2013-03-19 | 2014-09-25 | Merck Sharp & Dohme Corp. | Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors |
| WO2016061751A1 (en) * | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Ethyl n-boc piperidinyl pyrazolo pyridones as janus kinase inhibitors |
| CN105327207A (zh) * | 2015-12-07 | 2016-02-17 | 雷文金 | 一种治疗风湿热痹的中药组合物 |
| CN105435170A (zh) * | 2015-12-11 | 2016-03-30 | 张量才 | 一种食药同源的中药保健食品 |
| AU2018289759B2 (en) | 2017-06-23 | 2022-03-10 | Kyowa Kirin Co., Ltd. | Alpha, beta-unsaturated amide compound |
| US11098216B2 (en) | 2017-09-28 | 2021-08-24 | Ricoh Company, Ltd. | Image forming method, image forming apparatus, and method for manufacturing printed matter |
| EP3650447A1 (en) * | 2018-11-08 | 2020-05-13 | Universite de Nantes | New selective modulators of insect nicotinic acetylcholine receptors |
| CN111499592B (zh) * | 2020-03-14 | 2023-06-23 | 江苏省农用激素工程技术研究中心有限公司 | 5-氨甲基糖精的合成方法 |
| CN116157124A (zh) * | 2020-05-29 | 2023-05-23 | 大邱庆北尖端医疗产业振兴财团 | 磺胺衍生物和含其作为活性成分的用于预防或治疗精神疾病的药物组合物 |
| CN112694497A (zh) * | 2020-12-25 | 2021-04-23 | 蚌埠中实化学技术有限公司 | 一种4-异丙基磺酰基苯硼酸的制备方法 |
| EP4540230A1 (en) * | 2022-06-16 | 2025-04-23 | Ensem Therapeutics, Inc. | Anilino-pyrazole derivatives, compositions and methods thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2123651A4 (en) | 2007-01-12 | 2011-05-04 | Astellas Pharma Inc | CONDENSED PYRIDINE COMPOUND |
| CA2767079A1 (en) * | 2009-07-08 | 2011-01-13 | Leo Pharma A/S | Heterocyclic compounds as jak receptor and protein tyrosine kinase inhibitors |
| WO2011029804A1 (en) * | 2009-09-10 | 2011-03-17 | F. Hoffmann-La Roche Ag | Inhibitors of jak |
| MX354212B (es) | 2010-03-10 | 2018-02-19 | Incyte Corp | Derivados de piperidin-4-il azetidina como inhibidores de janus cinasa 1 (jak1). |
| WO2012127506A1 (en) * | 2011-03-22 | 2012-09-27 | Advinus Therapeutics Limited | Substituted fused tricyclic compounds, compositions and medicinal applications thereof |
| WO2013017479A1 (en) | 2011-07-29 | 2013-02-07 | Cellzome Limited | Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors |
| WO2013017480A1 (en) * | 2011-07-29 | 2013-02-07 | Cellzome Limited | Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors |
| JPWO2013180265A1 (ja) | 2012-06-01 | 2016-01-21 | 武田薬品工業株式会社 | 複素環化合物 |
-
2014
- 2014-03-19 RU RU2015144385A patent/RU2015144385A/ru not_active Application Discontinuation
- 2014-03-19 BR BR112015024050A patent/BR112015024050A2/pt not_active Application Discontinuation
- 2014-03-19 JP JP2016503523A patent/JP6305510B2/ja not_active Expired - Fee Related
- 2014-03-19 EP EP14770056.1A patent/EP2976341B1/en active Active
- 2014-03-19 US US14/778,055 patent/US10059705B2/en active Active
- 2014-03-19 KR KR1020157025520A patent/KR20150132170A/ko not_active Withdrawn
- 2014-03-19 CN CN201480016814.2A patent/CN105121444B/zh not_active Expired - Fee Related
- 2014-03-19 AU AU2014234909A patent/AU2014234909B2/en not_active Ceased
- 2014-03-19 MX MX2015013419A patent/MX2015013419A/es unknown
- 2014-03-19 CA CA2901770A patent/CA2901770A1/en not_active Abandoned
- 2014-03-19 WO PCT/CN2014/000299 patent/WO2014146493A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2976341A1 (en) | 2016-01-27 |
| BR112015024050A2 (pt) | 2017-07-18 |
| CA2901770A1 (en) | 2014-09-25 |
| JP6305510B2 (ja) | 2018-04-04 |
| WO2014146493A1 (en) | 2014-09-25 |
| AU2014234909A1 (en) | 2015-08-13 |
| RU2015144385A (ru) | 2017-04-26 |
| EP2976341B1 (en) | 2018-02-28 |
| AU2014234909B2 (en) | 2017-10-05 |
| US10059705B2 (en) | 2018-08-28 |
| EP2976341A4 (en) | 2016-10-12 |
| KR20150132170A (ko) | 2015-11-25 |
| CN105121444B (zh) | 2018-02-16 |
| US20160272634A1 (en) | 2016-09-22 |
| JP2016514711A (ja) | 2016-05-23 |
| CN105121444A (zh) | 2015-12-02 |
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