MX2015011676A - Inhibidores de leucotrieno a4 hidrolasa. - Google Patents
Inhibidores de leucotrieno a4 hidrolasa.Info
- Publication number
- MX2015011676A MX2015011676A MX2015011676A MX2015011676A MX2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A MX 2015011676 A MX2015011676 A MX 2015011676A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrolase
- leukotriene
- inhibitors
- methods
- diseases
- Prior art date
Links
- 102100022118 Leukotriene A-4 hydrolase Human genes 0.000 title abstract 2
- 108010072713 leukotriene A4 hydrolase Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 230000001668 ameliorated effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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| SI2268646T1 (sl) * | 2008-04-11 | 2013-12-31 | Janssen Pharmaceutica N.V. | Tiazolopiridin-2-iloksi-fenil in tiazolopirazin-2-iloksi-fenil amini kot modulatorji levkotrien a4 hidrolaze |
| EP2110374A1 (en) | 2008-04-18 | 2009-10-21 | Merck Sante | Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators |
| WO2010011912A1 (en) | 2008-07-25 | 2010-01-28 | Smithkline Beecham Corporation | Trpv4 antagonists |
| CN102030700B (zh) * | 2009-09-30 | 2016-06-01 | 中国医学科学院药物研究所 | 苯甲酰胺基羧酸类化合物及其制法和药物用途 |
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| JP2013047189A (ja) * | 2009-12-25 | 2013-03-07 | Kyorin Pharmaceutical Co Ltd | 新規パラバン酸誘導体及びそれらを有効成分とする医薬 |
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| TR201802550T4 (tr) * | 2011-03-14 | 2018-03-21 | Boehringer Ingelheim Int | Lökotrien üretiminin benzodioksan inhibitörleri. |
| BR112013023536A2 (pt) | 2011-03-15 | 2016-12-06 | Rib X Pharmaceuticals Inc | agentes antimicrobianos |
| ES2557450T3 (es) | 2011-05-23 | 2016-01-26 | Janssen Pharmaceutica, N.V. | Derivados de ácido picolinamido-propanoico útiles como antagonistas de los receptores de glucagón |
| US9006235B2 (en) | 2012-03-06 | 2015-04-14 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2014164658A1 (en) | 2013-03-12 | 2014-10-09 | Celtaxsys, Inc. | Methods of inhibiting leukotriene a4 hydrolase |
| EP2970309A4 (en) | 2013-03-14 | 2016-11-09 | Celtaxsys Inc | INHIBITORS OF LEUCOTRIENE A4 HYDROLASE |
| AU2014240042C1 (en) | 2013-03-14 | 2019-09-05 | Celltaxis, Llc | Inhibitors of leukotriene A4 hydrolase |
-
2014
- 2014-03-14 CA CA2906086A patent/CA2906086A1/en not_active Abandoned
- 2014-03-14 JP JP2016502444A patent/JP6562898B2/ja active Active
- 2014-03-14 MX MX2015011676A patent/MX2015011676A/es unknown
- 2014-03-14 KR KR1020157028770A patent/KR20150131211A/ko not_active Ceased
- 2014-03-14 BR BR112015022227A patent/BR112015022227A2/pt not_active Application Discontinuation
- 2014-03-14 RU RU2015137977A patent/RU2690489C2/ru not_active IP Right Cessation
- 2014-03-14 EP EP14769620.7A patent/EP2968265A4/en not_active Withdrawn
- 2014-03-14 WO PCT/US2014/027449 patent/WO2014152536A2/en not_active Ceased
- 2014-03-14 AU AU2014239585A patent/AU2014239585B2/en not_active Ceased
-
2015
- 2015-09-10 US US14/849,829 patent/US9822106B2/en not_active Expired - Fee Related
-
2017
- 2017-11-02 US US15/801,494 patent/US20180118735A1/en not_active Abandoned
-
2019
- 2019-07-02 AU AU2019204753A patent/AU2019204753A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2968265A4 (en) | 2016-12-28 |
| AU2014239585A1 (en) | 2015-09-24 |
| JP6562898B2 (ja) | 2019-08-21 |
| RU2015137977A3 (enExample) | 2018-03-27 |
| KR20150131211A (ko) | 2015-11-24 |
| CA2906086A1 (en) | 2014-09-25 |
| WO2014152536A3 (en) | 2014-11-27 |
| RU2015137977A (ru) | 2017-04-20 |
| AU2019204753A1 (en) | 2019-07-18 |
| RU2690489C2 (ru) | 2019-06-04 |
| US9822106B2 (en) | 2017-11-21 |
| WO2014152536A2 (en) | 2014-09-25 |
| JP2016516043A (ja) | 2016-06-02 |
| EP2968265A2 (en) | 2016-01-20 |
| AU2014239585B2 (en) | 2019-04-04 |
| BR112015022227A2 (pt) | 2017-07-18 |
| US20180118735A1 (en) | 2018-05-03 |
| US20160068522A1 (en) | 2016-03-10 |
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