MX2015000485A - Tratamiento de esclerosis multiple con una combinacion de laquinimod y fampridina. - Google Patents
Tratamiento de esclerosis multiple con una combinacion de laquinimod y fampridina.Info
- Publication number
- MX2015000485A MX2015000485A MX2015000485A MX2015000485A MX2015000485A MX 2015000485 A MX2015000485 A MX 2015000485A MX 2015000485 A MX2015000485 A MX 2015000485A MX 2015000485 A MX2015000485 A MX 2015000485A MX 2015000485 A MX2015000485 A MX 2015000485A
- Authority
- MX
- Mexico
- Prior art keywords
- fampridine
- laquinimod
- multiple sclerosis
- combination
- presenting
- Prior art date
Links
- NUKYPUAOHBNCPY-UHFFFAOYSA-N 4-aminopyridine Chemical compound NC1=CC=NC=C1 NUKYPUAOHBNCPY-UHFFFAOYSA-N 0.000 title abstract 6
- 229960004979 fampridine Drugs 0.000 title abstract 6
- 229960004577 laquinimod Drugs 0.000 title abstract 6
- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 title abstract 6
- 201000006417 multiple sclerosis Diseases 0.000 title abstract 6
- 206010071068 Clinically isolated syndrome Diseases 0.000 abstract 5
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261670758P | 2012-07-12 | 2012-07-12 | |
| PCT/US2013/050001 WO2014011827A1 (en) | 2012-07-12 | 2013-07-11 | Treatment of multiple sclerosis with combination of laquinimod and fampridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015000485A true MX2015000485A (es) | 2015-04-08 |
Family
ID=49914160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015000485A MX2015000485A (es) | 2012-07-12 | 2013-07-11 | Tratamiento de esclerosis multiple con una combinacion de laquinimod y fampridina. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20140017226A1 (enExample) |
| EP (1) | EP2872217A4 (enExample) |
| JP (1) | JP2015522077A (enExample) |
| KR (1) | KR20150038072A (enExample) |
| CN (1) | CN104582793A (enExample) |
| AR (1) | AR091724A1 (enExample) |
| AU (1) | AU2013290181A1 (enExample) |
| BR (1) | BR112015000616A2 (enExample) |
| CA (1) | CA2873229A1 (enExample) |
| EA (1) | EA201590191A1 (enExample) |
| HK (1) | HK1209672A1 (enExample) |
| IL (1) | IL236230A0 (enExample) |
| MX (1) | MX2015000485A (enExample) |
| TW (1) | TW201408300A (enExample) |
| UY (1) | UY34896A (enExample) |
| WO (1) | WO2014011827A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106063787A (zh) | 2012-02-03 | 2016-11-02 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| KR20140138725A (ko) | 2012-02-16 | 2014-12-04 | 테바 파마슈티컬 인더스트리즈 리미티드 | N-에틸-n-페닐-1,2-디하이드로-4,5-디-하이드록시-1-메틸-2-옥소-3-퀴놀린카복사미드, 그의 제조 및 용도 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
| HK1212936A1 (zh) | 2012-11-07 | 2016-06-24 | Teva Pharmaceutical Industries Ltd. | 拉喹莫德胺盐 |
| NZ630427A (en) | 2013-03-14 | 2017-06-30 | Teva Pharma | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| UY36099A (es) | 2014-04-29 | 2016-02-29 | Teva Pharma | Laquinimod para el tratamiento de pacientes con esclerosis múltiple remitente recurrente (rrms) con un alto grado de discapacidad |
| GB2540163A (en) * | 2015-07-07 | 2017-01-11 | Univ London Queen Mary | Combination therapy for treating multiple sclerosis |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9726339D0 (en) * | 1997-12-13 | 1998-02-11 | Zeneca Ltd | Human-derived tissue-specific potassium channel |
| US20090082471A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched fingolimod |
| ES2329327B1 (es) * | 2008-03-19 | 2010-09-17 | Proyecto De Biomedicina Cima, S.L. | Combinaciones sinergicas de 5'-metiltioadenosina. |
| AU2009291781A1 (en) * | 2008-09-10 | 2010-03-18 | Acorda Therapeutics, Inc. | Methods of using sustained release aminopyridine compositions |
| CN107308162A (zh) * | 2009-06-19 | 2017-11-03 | 泰华制药工业有限公司 | 利用拉喹莫德治疗多发性硬化 |
| SG11201401330YA (en) * | 2011-10-12 | 2014-05-29 | Teva Pharma | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
-
2013
- 2013-07-09 UY UY0001034896A patent/UY34896A/es not_active Application Discontinuation
- 2013-07-10 TW TW102124792A patent/TW201408300A/zh unknown
- 2013-07-10 AR ARP130102454 patent/AR091724A1/es unknown
- 2013-07-11 WO PCT/US2013/050001 patent/WO2014011827A1/en not_active Ceased
- 2013-07-11 CN CN201380037036.0A patent/CN104582793A/zh active Pending
- 2013-07-11 AU AU2013290181A patent/AU2013290181A1/en not_active Abandoned
- 2013-07-11 KR KR1020157003858A patent/KR20150038072A/ko not_active Withdrawn
- 2013-07-11 EA EA201590191A patent/EA201590191A1/ru unknown
- 2013-07-11 BR BR112015000616A patent/BR112015000616A2/pt not_active IP Right Cessation
- 2013-07-11 CA CA2873229A patent/CA2873229A1/en not_active Abandoned
- 2013-07-11 HK HK15110240.0A patent/HK1209672A1/xx unknown
- 2013-07-11 JP JP2015521792A patent/JP2015522077A/ja active Pending
- 2013-07-11 EP EP13816075.9A patent/EP2872217A4/en not_active Withdrawn
- 2013-07-11 MX MX2015000485A patent/MX2015000485A/es unknown
- 2013-07-11 US US13/939,306 patent/US20140017226A1/en not_active Abandoned
-
2014
- 2014-12-14 IL IL236230A patent/IL236230A0/en unknown
-
2016
- 2016-04-21 US US15/135,280 patent/US20160235735A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW201408300A (zh) | 2014-03-01 |
| BR112015000616A2 (pt) | 2017-06-27 |
| AR091724A1 (es) | 2015-02-25 |
| US20140017226A1 (en) | 2014-01-16 |
| CA2873229A1 (en) | 2014-01-16 |
| IL236230A0 (en) | 2015-01-29 |
| KR20150038072A (ko) | 2015-04-08 |
| UY34896A (es) | 2014-02-28 |
| JP2015522077A (ja) | 2015-08-03 |
| EA201590191A1 (ru) | 2015-06-30 |
| AU2013290181A1 (en) | 2015-02-26 |
| WO2014011827A1 (en) | 2014-01-16 |
| EP2872217A4 (en) | 2016-03-16 |
| US20160235735A1 (en) | 2016-08-18 |
| CN104582793A (zh) | 2015-04-29 |
| EP2872217A1 (en) | 2015-05-20 |
| HK1209672A1 (en) | 2016-04-08 |
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