MX2014012234A - Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas. - Google Patents
Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas.Info
- Publication number
- MX2014012234A MX2014012234A MX2014012234A MX2014012234A MX2014012234A MX 2014012234 A MX2014012234 A MX 2014012234A MX 2014012234 A MX2014012234 A MX 2014012234A MX 2014012234 A MX2014012234 A MX 2014012234A MX 2014012234 A MX2014012234 A MX 2014012234A
- Authority
- MX
- Mexico
- Prior art keywords
- rsv
- nucleic acid
- methods
- disclosed
- sequences
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describen moléculas de ácido nucleico y composiciones que comprenden una o más secuencias de ácido nucleico que codifican un antígeno RSV. El ácido nucleico se describe comprendiendo las secuencias que codifican la proteína RSV F de consenso o uno de sus fragmentos inmunogénicos, secuencias que codifican a la proteína RSV G(A) o uno de sus fragmentos inmunogénicos y secuencias que codifican la proteína RSV G(B) o uno de sus fragmentos inmunogénicos. Las composiciones que comprende una, combinaciones de dos o las tres secuencias se describen. Las secuencias de codificación opcionalmente incluyen la secuencia de codificación operablemente enlazada que codifica un péptido de señal. Las moléculas de ácido nucleico y las composiciones que comprenden la quimiocina CC20 y/o una proteína RSV M2-1 de consenso o uno de sus fragmentos inmunogénicos también se describen. Los métodos inmunomoduladores e incluyendo métodos para inducir unan respuesta inmunitaria frente a RSV se describen. El método para la prevención de la infección por RSV y métodos para el tratamiento de individuos afectados con RSV se describen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261622279P | 2012-04-10 | 2012-04-10 | |
PCT/US2013/036008 WO2013155205A1 (en) | 2012-04-10 | 2013-04-10 | Human respiratory syncytial virus concensus antigens, nucleic acid constructs and vaccines made thereform, and methods of using same |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014012234A true MX2014012234A (es) | 2014-12-05 |
MX363667B MX363667B (es) | 2019-03-29 |
Family
ID=49328131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014012234A MX363667B (es) | 2012-04-10 | 2013-04-10 | Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas. |
MX2019003682A MX2019003682A (es) | 2012-04-10 | 2014-10-09 | Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019003682A MX2019003682A (es) | 2012-04-10 | 2014-10-09 | Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas. |
Country Status (10)
Country | Link |
---|---|
US (2) | US10040828B2 (es) |
EP (2) | EP2836505B1 (es) |
JP (3) | JP2015514132A (es) |
KR (1) | KR20140146651A (es) |
CN (1) | CN104619719A (es) |
AU (1) | AU2013245950B2 (es) |
CA (1) | CA2870182A1 (es) |
HK (1) | HK1210479A1 (es) |
MX (2) | MX363667B (es) |
WO (1) | WO2013155205A1 (es) |
Families Citing this family (12)
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US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
CN106018780B (zh) * | 2016-05-17 | 2017-12-26 | 扬州大学 | 一种基于f1蛋白的检测4型禽腺病毒抗体的间接免疫荧光试剂盒 |
MA50335A (fr) | 2016-12-08 | 2020-08-19 | Modernatx Inc | Vaccins à acide nucléique contre des virus respiratoires |
EP3595713A4 (en) | 2017-03-15 | 2021-01-13 | ModernaTX, Inc. | RESPIRATORY SYNCYTIAL VIRUS VACCINE |
US20200030432A1 (en) | 2017-03-17 | 2020-01-30 | Modernatx, Inc. | Zoonotic disease rna vaccines |
RU2019130167A (ru) | 2017-04-04 | 2021-05-05 | Юниверсити Оф Вашингтон | Самосборные белковые наноструктуры, экспонирующие f-белки парамиксовируса и/или пневмовируса, и их применение |
US11786607B2 (en) | 2017-06-15 | 2023-10-17 | Modernatx, Inc. | RNA formulations |
US11376317B2 (en) | 2017-08-30 | 2022-07-05 | University Of Maryland, College Park | FcRn-targeted mucosal vaccination against RSV |
AU2018326799A1 (en) | 2017-08-31 | 2020-02-27 | Modernatx, Inc. | Methods of making lipid nanoparticles |
US11911453B2 (en) | 2018-01-29 | 2024-02-27 | Modernatx, Inc. | RSV RNA vaccines |
US11771755B2 (en) | 2018-02-28 | 2023-10-03 | University Of Washington | Self-asssembling nanostructure vaccines |
US11591371B2 (en) | 2018-04-02 | 2023-02-28 | University Of Maryland, College Park | FcRn-targeted mucosal vaccination against influenza infections |
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2013
- 2013-04-10 JP JP2015505881A patent/JP2015514132A/ja active Pending
- 2013-04-10 WO PCT/US2013/036008 patent/WO2013155205A1/en active Application Filing
- 2013-04-10 KR KR1020147031459A patent/KR20140146651A/ko not_active Application Discontinuation
- 2013-04-10 MX MX2014012234A patent/MX363667B/es unknown
- 2013-04-10 EP EP13775839.7A patent/EP2836505B1/en active Active
- 2013-04-10 US US14/391,921 patent/US10040828B2/en active Active
- 2013-04-10 EP EP19153155.7A patent/EP3511337A1/en not_active Withdrawn
- 2013-04-10 CA CA2870182A patent/CA2870182A1/en not_active Abandoned
- 2013-04-10 CN CN201380029394.7A patent/CN104619719A/zh active Pending
- 2013-04-10 AU AU2013245950A patent/AU2013245950B2/en not_active Ceased
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2014
- 2014-10-09 MX MX2019003682A patent/MX2019003682A/es unknown
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2015
- 2015-11-12 HK HK15111189.1A patent/HK1210479A1/xx unknown
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2017
- 2017-11-20 JP JP2017222722A patent/JP2018065824A/ja active Pending
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2018
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2019
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US10040828B2 (en) | 2018-08-07 |
JP2015514132A (ja) | 2015-05-18 |
US20150079121A1 (en) | 2015-03-19 |
WO2013155205A1 (en) | 2013-10-17 |
WO2013155205A9 (en) | 2013-12-05 |
MX2019003682A (es) | 2019-07-18 |
US20180346522A1 (en) | 2018-12-06 |
EP2836505A4 (en) | 2015-12-02 |
MX363667B (es) | 2019-03-29 |
HK1210479A1 (en) | 2016-04-22 |
CA2870182A1 (en) | 2013-10-17 |
CN104619719A (zh) | 2015-05-13 |
KR20140146651A (ko) | 2014-12-26 |
AU2013245950B2 (en) | 2016-04-21 |
JP2018065824A (ja) | 2018-04-26 |
EP3511337A1 (en) | 2019-07-17 |
US11021520B2 (en) | 2021-06-01 |
EP2836505A1 (en) | 2015-02-18 |
EP2836505B1 (en) | 2019-01-23 |
JP2019112414A (ja) | 2019-07-11 |
AU2013245950A1 (en) | 2014-10-30 |
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