MX2014005710A - Un metodo de cribado de farmaco y usos del mismo. - Google Patents

Un metodo de cribado de farmaco y usos del mismo.

Info

Publication number
MX2014005710A
MX2014005710A MX2014005710A MX2014005710A MX2014005710A MX 2014005710 A MX2014005710 A MX 2014005710A MX 2014005710 A MX2014005710 A MX 2014005710A MX 2014005710 A MX2014005710 A MX 2014005710A MX 2014005710 A MX2014005710 A MX 2014005710A
Authority
MX
Mexico
Prior art keywords
methods
pharmacomap
predicting
screening method
drug screening
Prior art date
Application number
MX2014005710A
Other languages
English (en)
Inventor
Pavel Osten
Original Assignee
Cold Spring Harbor Lab An Education Corp Of The State Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab An Education Corp Of The State Of New York filed Critical Cold Spring Harbor Lab An Education Corp Of The State Of New York
Publication of MX2014005710A publication Critical patent/MX2014005710A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes

Abstract

Se describen en la presente los métodos para el cribado de fármacos en un animal no humano usando la tecnología de alta resolución que conduce a la generación de mapas farmacológicos. Además se describen en la presente los métodos para predecir el beneficio terapéutico y/o la toxicidad de los compuestos candidatos del fármaco. En las modalidades específicas, se proporcionan en la presente los métodos para predecir los efectos clínicos de un fármaco de prueba con base en la comparación del mapa farmacológico del fármaco de prueba con uno o más fármacos de referencia con los resultados clínicos conocidos.
MX2014005710A 2011-11-11 2012-11-09 Un metodo de cribado de farmaco y usos del mismo. MX2014005710A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161558877P 2011-11-11 2011-11-11
PCT/US2012/064440 WO2013071099A1 (en) 2011-11-11 2012-11-09 A drug screening method and uses thereof

Publications (1)

Publication Number Publication Date
MX2014005710A true MX2014005710A (es) 2015-03-09

Family

ID=48290605

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005710A MX2014005710A (es) 2011-11-11 2012-11-09 Un metodo de cribado de farmaco y usos del mismo.

Country Status (8)

Country Link
US (1) US20140297199A1 (es)
EP (1) EP2777074A4 (es)
JP (1) JP2015507470A (es)
CN (1) CN104040719A (es)
CA (1) CA2854469A1 (es)
IN (1) IN2014MN01101A (es)
MX (1) MX2014005710A (es)
WO (1) WO2013071099A1 (es)

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CN104850864A (zh) * 2015-06-01 2015-08-19 深圳英智源智能系统有限公司 一种基于卷积神经网络的非监督图像识别方法
US11462303B2 (en) * 2016-09-12 2022-10-04 Cornell University Computational systems and methods for improving the accuracy of drug toxicity predictions
JP7197477B2 (ja) * 2016-11-18 2022-12-27 ティシュヴィジョン、インコーポレーテッド 自動化された組織切片の捕捉、指標付けおよび保管システム
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JP6559850B1 (ja) * 2018-07-27 2019-08-14 Ｋａｒｙｄｏ ＴｈｅｒａｐｅｕｔｉＸ株式会社 ヒトにおける被験物質の作用を予測するための人工知能モデル
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EP3644228A1 (en) * 2018-10-23 2020-04-29 The Chinese University Of Hong Kong Method and apparatus for segmenting cellular image
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KR102307479B1 (ko) * 2019-02-12 2021-09-30 단국대학교 천안캠퍼스 산학협력단 신경전달물질 기반의 뇌 지도 작성 방법 및 뇌 지도를 이용하는 용도
CN109709129A (zh) * 2019-02-13 2019-05-03 李秀利 一种高通量筛选药物的磁共振成像方法
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CN110178757B (zh) * 2019-04-19 2021-08-27 广东医科大学附属医院 一种斑马鱼脑创伤模型及其制备方法和应用
JP2022544278A (ja) * 2019-08-13 2022-10-17 サノフイ 化学物質に対する患者の反応の予測
CN114556481A (zh) * 2019-10-17 2022-05-27 无限生物制药公司 用于预测测试物质在人类中的适应症的人工智能模型
CN110850070B (zh) * 2019-11-22 2021-06-01 北京大学 一种基于荧光标记转基因动物模型评价化学物质生殖发育毒性的方法
CN111061729B (zh) * 2019-11-29 2021-04-16 武汉大学 顾及粒度的矢量瓦片组织方法
US20210190762A1 (en) * 2019-12-06 2021-06-24 The Broad Institute, Inc. Living biosensors
CN111062346A (zh) * 2019-12-21 2020-04-24 电子科技大学 一种白细胞自动定位检测及分类识别系统及方法
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Also Published As

Publication number Publication date
EP2777074A1 (en) 2014-09-17
CN104040719A (zh) 2014-09-10
CA2854469A1 (en) 2013-05-16
JP2015507470A (ja) 2015-03-12
IN2014MN01101A (es) 2015-07-03
WO2013071099A1 (en) 2013-05-16
EP2777074A4 (en) 2015-08-19
US20140297199A1 (en) 2014-10-02

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