MX2013005009A - Metodo para la elaboracion de naltrexona. - Google Patents

Metodo para la elaboracion de naltrexona.

Info

Publication number
MX2013005009A
MX2013005009A MX2013005009A MX2013005009A MX2013005009A MX 2013005009 A MX2013005009 A MX 2013005009A MX 2013005009 A MX2013005009 A MX 2013005009A MX 2013005009 A MX2013005009 A MX 2013005009A MX 2013005009 A MX2013005009 A MX 2013005009A
Authority
MX
Mexico
Prior art keywords
naltrexone
manufacturing
dihydroxy
epoxy
cyclopropylmethyl
Prior art date
Application number
MX2013005009A
Other languages
English (en)
Spanish (es)
Inventor
Florian Anton Martin Huber
Carla De Faveri
Mariano Stivanello
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MX2013005009A publication Critical patent/MX2013005009A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2013005009A 2010-11-05 2011-11-04 Metodo para la elaboracion de naltrexona. MX2013005009A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41040510P 2010-11-05 2010-11-05
DKPA201001007 2010-11-05
US201161489701P 2011-05-25 2011-05-25
DKPA201100396 2011-05-25
PCT/DK2011/000128 WO2012059103A1 (en) 2010-11-05 2011-11-04 Method for the manufacturing of naltrexone

Publications (1)

Publication Number Publication Date
MX2013005009A true MX2013005009A (es) 2013-08-01

Family

ID=45001588

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013005009A MX2013005009A (es) 2010-11-05 2011-11-04 Metodo para la elaboracion de naltrexona.

Country Status (20)

Country Link
EP (1) EP2635586B1 (enExample)
JP (2) JP6246589B2 (enExample)
AP (1) AP3415A (enExample)
AU (1) AU2011325563B2 (enExample)
CA (1) CA2815093C (enExample)
CY (1) CY1118742T1 (enExample)
DK (1) DK2635586T3 (enExample)
EA (1) EA022266B1 (enExample)
ES (1) ES2620660T3 (enExample)
HR (1) HRP20170379T1 (enExample)
HU (1) HUE033596T2 (enExample)
LT (1) LT2635586T (enExample)
ME (1) ME02621B (enExample)
MX (1) MX2013005009A (enExample)
PL (1) PL2635586T3 (enExample)
PT (1) PT2635586T (enExample)
RS (1) RS55777B1 (enExample)
SI (1) SI2635586T1 (enExample)
SM (1) SMT201700177T1 (enExample)
WO (1) WO2012059103A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140005217A1 (en) 2012-06-27 2014-01-02 H. Lundbeck A/S Nalmefene for reduction of alcohol consumption in specific target populations
AR096851A1 (es) 2013-07-11 2016-02-03 H Lundbeck As Sales que no forman hidratos ni solvatos de nalmefeno
AU2014368548B2 (en) 2013-12-20 2019-09-19 H. Lundbeck A/S Use of an opioid receptor antagonist with kappa-activity and vortioxetine for treatment of depressive disorder with melancholic features
MX2016013889A (es) 2014-04-22 2017-03-09 Otsuka Pharma Co Ltd Medicamento.
US9701688B2 (en) * 2014-05-05 2017-07-11 Noramco, Inc. Process for the preparation of opioid compounds
US9701687B2 (en) * 2014-05-05 2017-07-11 Noramco, Inc. Process for the preparation of opioid compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535157A (en) 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4751307A (en) 1985-01-17 1988-06-14 Mallinckrodt, Inc. Wittig-reaction processes
ATE178329T1 (de) * 1989-10-16 1999-04-15 Us Health Totale synthese von northebain-, normorphin-, noroxymorphon-enantiomeren und -derivaten via n- nor-zwischenverbindungen
FR2906252B1 (fr) 2006-09-21 2008-11-28 Sanofi Aventis Sa Procede de preparation d'halogenures de n-aklyl naltrexone
WO2008138383A1 (de) 2007-05-16 2008-11-20 Cilag Ag Verfahren zur herstellung von n-methylnaltrexonbromid
ES2566559T3 (es) 2008-09-30 2016-04-13 Mallinckrodt Llc Procesos para la alquilación de grupos amino secundarios de derivados de morfinano
JP5794980B2 (ja) 2009-05-25 2015-10-14 ハー・ルンドベック・アクチエゼルスカベット ナルトレキソンからの塩酸ナルメフェンの調製

Also Published As

Publication number Publication date
CY1118742T1 (el) 2017-07-12
AU2011325563A1 (en) 2013-05-02
DK2635586T3 (en) 2017-03-27
JP2016199566A (ja) 2016-12-01
ME02621B (me) 2017-06-20
EP2635586B1 (en) 2017-02-08
JP6246589B2 (ja) 2017-12-13
AP3415A (en) 2015-09-30
SMT201700177T1 (it) 2017-05-08
RS55777B1 (sr) 2017-07-31
ES2620660T3 (es) 2017-06-29
AU2011325563B2 (en) 2015-08-20
HUE033596T2 (hu) 2017-12-28
PL2635586T3 (pl) 2017-06-30
EP2635586A1 (en) 2013-09-11
HRP20170379T1 (hr) 2017-05-05
JP2013541564A (ja) 2013-11-14
JP6215399B2 (ja) 2017-10-18
AP2013006897A0 (en) 2013-05-31
SI2635586T1 (sl) 2017-07-31
LT2635586T (lt) 2017-04-10
EA022266B1 (ru) 2015-11-30
EA201390658A1 (ru) 2013-11-29
WO2012059103A1 (en) 2012-05-10
CA2815093C (en) 2019-08-06
CA2815093A1 (en) 2012-05-10
PT2635586T (pt) 2017-03-30

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