MX2013002409A - Antagonistas del receptor 5-ht2b. - Google Patents

Antagonistas del receptor 5-ht2b.

Info

Publication number
MX2013002409A
MX2013002409A MX2013002409A MX2013002409A MX2013002409A MX 2013002409 A MX2013002409 A MX 2013002409A MX 2013002409 A MX2013002409 A MX 2013002409A MX 2013002409 A MX2013002409 A MX 2013002409A MX 2013002409 A MX2013002409 A MX 2013002409A
Authority
MX
Mexico
Prior art keywords
ht2b receptor
receptor antagonists
ht2b
medicine
prevention
Prior art date
Application number
MX2013002409A
Other languages
English (en)
Spanish (es)
Inventor
Donck Luc August Laurentius Ver
Johannes Wilhelmus John F Thuring
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2013002409A publication Critical patent/MX2013002409A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2013002409A 2010-09-01 2011-08-30 Antagonistas del receptor 5-ht2b. MX2013002409A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10174880 2010-09-01
PCT/EP2011/064906 WO2012028614A1 (en) 2010-09-01 2011-08-30 5-ht2b receptor antagonists

Publications (1)

Publication Number Publication Date
MX2013002409A true MX2013002409A (es) 2013-04-03

Family

ID=43127285

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002409A MX2013002409A (es) 2010-09-01 2011-08-30 Antagonistas del receptor 5-ht2b.

Country Status (14)

Country Link
US (2) US8703958B2 (enExample)
EP (1) EP2619180B1 (enExample)
JP (1) JP5845263B2 (enExample)
KR (1) KR101815123B1 (enExample)
CN (1) CN103080089B (enExample)
AU (1) AU2011298361B2 (enExample)
BR (1) BR112013004503A2 (enExample)
CA (1) CA2806647C (enExample)
EA (1) EA020967B1 (enExample)
ES (1) ES2525515T3 (enExample)
MX (1) MX2013002409A (enExample)
SG (1) SG188233A1 (enExample)
WO (1) WO2012028614A1 (enExample)
ZA (1) ZA201301561B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2525515T3 (es) 2010-09-01 2014-12-23 Janssen Pharmaceutica, N.V. Antagonistas del receptor 5-HT2B
CN103467596A (zh) * 2012-06-06 2013-12-25 北京大学 一个治疗肺动脉高压的新靶点
US20170058349A1 (en) * 2014-03-04 2017-03-02 The Children's Hospital Of Philadelphia Methods for managing care of patients predisposed to progressive mitral valve diseases
CN110950843B (zh) * 2019-11-28 2022-12-27 广东东阳光药业有限公司 取代的苯酰胺衍生物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
GB8519707D0 (en) * 1985-08-06 1985-09-11 Fordonal Sa Chemical compounds
CA1317940C (en) * 1987-09-25 1993-05-18 Georges H. P. Van Daele Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides
US6552046B2 (en) * 2000-06-07 2003-04-22 Aryx Therapeutics Materials and methods for the treatment of gastroesophageal reflux disease
US6444477B1 (en) * 2000-11-28 2002-09-03 Pharmagene Laboratories Limited Assay method for detecting 5-HT2B antagonists
CN1918157B (zh) * 2004-01-07 2010-06-23 ARYx医疗有限公司 立体异构化合物及治疗胃肠道和中枢神经系统紊乱的方法
BRPI0620196A2 (pt) 2005-12-23 2013-01-15 Astrazeneca Ab composto, processo para a preparaÇço do mesmo, composiÇço farmacÊutica, uso de um composto, e, mÉtodos para a produÇço de um efeito antibacteriano em um animal de sangue quente, para a inibiÇço de dna girase e/ou topoisomerase iv bacteriana em um animal de sangue quente e para o tratamento de uma infecÇço bacteriana em um animal de sangue quente
WO2008139152A1 (en) * 2007-05-11 2008-11-20 Sentinel Oncology Limited N-oxide-containing pharmaceutical compounds
ES2525515T3 (es) 2010-09-01 2014-12-23 Janssen Pharmaceutica, N.V. Antagonistas del receptor 5-HT2B

Also Published As

Publication number Publication date
CN103080089A (zh) 2013-05-01
KR20130101503A (ko) 2013-09-13
JP5845263B2 (ja) 2016-01-20
EP2619180A1 (en) 2013-07-31
ZA201301561B (en) 2014-08-27
KR101815123B1 (ko) 2018-01-04
EA020967B1 (ru) 2015-03-31
SG188233A1 (en) 2013-04-30
US20130172386A1 (en) 2013-07-04
US20140187585A1 (en) 2014-07-03
US8703958B2 (en) 2014-04-22
CA2806647C (en) 2018-09-18
JP2013536823A (ja) 2013-09-26
WO2012028614A1 (en) 2012-03-08
AU2011298361B2 (en) 2014-03-13
US9139523B2 (en) 2015-09-22
EP2619180B1 (en) 2014-10-08
CN103080089B (zh) 2015-09-23
BR112013004503A2 (pt) 2016-06-07
HK1182097A1 (zh) 2013-11-22
EA201390312A1 (ru) 2013-07-30
ES2525515T3 (es) 2014-12-23
CA2806647A1 (en) 2012-03-08
AU2011298361A1 (en) 2013-02-14

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