MX2013001327A - Uso de hmgb1 como marcador biologico de afecciones intestinales inflamatorias, metodo no invasivo para su deteccion en muestras fecales y kit para su realizacion. - Google Patents

Uso de hmgb1 como marcador biologico de afecciones intestinales inflamatorias, metodo no invasivo para su deteccion en muestras fecales y kit para su realizacion.

Info

Publication number
MX2013001327A
MX2013001327A MX2013001327A MX2013001327A MX2013001327A MX 2013001327 A MX2013001327 A MX 2013001327A MX 2013001327 A MX2013001327 A MX 2013001327A MX 2013001327 A MX2013001327 A MX 2013001327A MX 2013001327 A MX2013001327 A MX 2013001327A
Authority
MX
Mexico
Prior art keywords
hmgbl
protein
hmgb1
antibody
fecal
Prior art date
Application number
MX2013001327A
Other languages
English (en)
Spanish (es)
Inventor
Salvatore Cucchiara
Laura Stronati
Roberta Vitali
Original Assignee
Dmg Italia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dmg Italia Srl filed Critical Dmg Italia Srl
Publication of MX2013001327A publication Critical patent/MX2013001327A/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2013001327A 2010-08-05 2011-08-01 Uso de hmgb1 como marcador biologico de afecciones intestinales inflamatorias, metodo no invasivo para su deteccion en muestras fecales y kit para su realizacion. MX2013001327A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2010A000442A IT1406051B1 (it) 2010-08-05 2010-08-05 Uso di hmgb1 come marcatore biologico di infiammazione intestinale umana, metodo non invasivo per la sua rilevazione in campioni fecali e kit relativo.
PCT/IT2011/000276 WO2012017466A1 (en) 2010-08-05 2011-08-01 Use of hmgb1 as' a biological marker of bowel inflammatory conditions, non-invasive method for its detection in fecal samples and kit thereof

Publications (1)

Publication Number Publication Date
MX2013001327A true MX2013001327A (es) 2013-03-08

Family

ID=43739596

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013001327A MX2013001327A (es) 2010-08-05 2011-08-01 Uso de hmgb1 como marcador biologico de afecciones intestinales inflamatorias, metodo no invasivo para su deteccion en muestras fecales y kit para su realizacion.

Country Status (14)

Country Link
US (1) US20130137123A1 (https=)
EP (1) EP2601525A1 (https=)
JP (1) JP2013534313A (https=)
CN (1) CN103069276A (https=)
AU (1) AU2011287193B2 (https=)
BR (1) BR112013002145A2 (https=)
CA (1) CA2807107C (https=)
CL (1) CL2013000223A1 (https=)
EA (1) EA201390197A1 (https=)
IL (1) IL223845A (https=)
IT (1) IT1406051B1 (https=)
MX (1) MX2013001327A (https=)
PE (1) PE20131062A1 (https=)
WO (1) WO2012017466A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015067913A1 (en) 2013-11-07 2015-05-14 Diagnodus Limited Biomarkers
DK2968443T3 (da) 2013-03-15 2021-12-06 Protagonist Therapeutics Inc Hepcidinanaloger og anvendelser deraf
PT3143037T (pt) 2014-05-16 2021-09-24 Protagonist Therapeutics Inc Antagonistas peptídicos tioéter de integrina alfa4beta7
US9624268B2 (en) 2014-07-17 2017-04-18 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
US20200064357A1 (en) * 2016-11-09 2020-02-27 Protagonist Therapeutics, Inc. Methods for determining and monitoring gastrointestinal inflammation
PL3622082T3 (pl) 2017-05-12 2023-07-31 Evonik Operations Gmbh Sposób wykrywania chorób wywołanych przez C. perfringens w stadzie ptaków
IT201700083044A1 (it) 2017-07-20 2019-01-20 Laura Stronati “uso della gelsolina come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali”
IT201700083055A1 (it) 2017-07-20 2019-01-20 Laura Stronati “uso della proteina inibitore 2 della dissociazione di rho gdp come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali”
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
US12031991B2 (en) * 2018-03-02 2024-07-09 Evonik Operations Gmbh In vitro method for detecting intestinal barrier failure in animals
CN109030817A (zh) * 2018-07-04 2018-12-18 长沙都正医学检验有限责任公司 Hmgb1检测试剂盒及其制备方法
TW202019948A (zh) 2018-07-12 2020-06-01 美商領導醫療有限公司 介白素-23受體之肽抑制劑及其治療發炎疾病之用途
DK3894863T3 (en) 2018-12-14 2023-02-20 Evonik Operations Gmbh In vitro-fremgangsmåde til påvisning af aviær intestinal dysbiose
US11684653B2 (en) * 2019-03-06 2023-06-27 The Cleveland Clinic Foundation Compositions and method for reducing virulence of microorganisms
HRP20250769T1 (hr) 2020-01-15 2025-08-29 Janssen Biotech, Inc. Peptidni inhibitori receptora za interleukin-23 i njihova uporaba u liječenju upalnih bolesti
AU2021209086A1 (en) 2020-01-15 2022-08-04 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
AU2021383828A1 (en) 2020-11-20 2023-07-06 Janssen Pharmaceutica Nv Compositions of peptide inhibitors of interleukin-23 receptor
WO2023288019A2 (en) 2021-07-14 2023-01-19 Janssen Biotech, Inc. Lipidated peptide inhibitors of interleukin-23 receptor
CN116973572B (zh) * 2023-06-02 2025-03-07 东南大学附属中大医院 基于血、粪便铁蛋白检测评估肠屏障损伤严重程度的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6822078B2 (en) * 1996-07-17 2004-11-23 Kaneka Corp. Diagnostic drugs for autoimmune diseases
US6355623B2 (en) * 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage
US6303321B1 (en) * 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US7700307B2 (en) * 2003-03-08 2010-04-20 Auvation Limited Mitochondrial stress-70 protein markers for colorectal cancer
US7585504B2 (en) * 2004-10-22 2009-09-08 Medimmune, Llc High affinity antibodies against HMGB1 and methods of use thereof
US20090297546A1 (en) * 2006-12-20 2009-12-03 Shino-Test Corporation Avian-derived antibody capable of binding specifically to human hmgb1, immunological determination method for human hmgb1, and immunological determination reagent for human hmgb1
EA201000131A1 (ru) * 2007-08-02 2010-08-30 АйЭсЭс ИММЬЮН СИСТЕМ СТИМУЛЕЙШН АБ Диагностика, определение стадии и мониторинг воспалительного заболевания кишечника
US7879553B2 (en) * 2008-03-14 2011-02-01 Exagen Diagnostics, Inc. Biomarkers for inflammatory bowel disease and irritable bowel syndrome

Also Published As

Publication number Publication date
AU2011287193B2 (en) 2015-08-13
WO2012017466A8 (en) 2013-07-11
EA201390197A1 (ru) 2013-06-28
JP2013534313A (ja) 2013-09-02
CN103069276A (zh) 2013-04-24
AU2011287193A1 (en) 2013-06-13
ITRM20100442A1 (it) 2012-02-06
WO2012017466A1 (en) 2012-02-09
IT1406051B1 (it) 2014-02-06
CA2807107C (en) 2017-01-03
PE20131062A1 (es) 2013-10-16
CL2013000223A1 (es) 2014-03-28
CA2807107A1 (en) 2012-02-09
EP2601525A1 (en) 2013-06-12
BR112013002145A2 (pt) 2016-05-24
US20130137123A1 (en) 2013-05-30
IL223845A (en) 2016-06-30

Similar Documents

Publication Publication Date Title
CA2807107C (en) Use of hmgb1 as a biological marker of bowel inflammatory conditions, non-invasive method for its detection in fecal samples and kit thereof
Sakurai et al. Positioning and usefulness of biomarkers in inflammatory bowel disease
Roda et al. Crohn’s disease
Kaiser et al. Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome
Orlando et al. The role of calprotectin in predicting endoscopic post-surgical recurrence in asymptomatic Crohn's disease: a comparison with ultrasound
Yaegashi et al. Evaluation of a newly identified soluble CD14 subtype as a marker for sepsis
Carroccio et al. Fecal assays detect hypersensitivity to cow's milk protein and gluten in adults with irritable bowel syndrome
Palone et al. Fecal HMGB1 reveals microscopic inflammation in adult and pediatric patients with inflammatory bowel disease in clinical and endoscopic remission
US20120276060A1 (en) Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
Angulo et al. Faecal calprotectin, an useful marker in discriminating between inflammatory bowel disease and functional gastrointestinal disorders
KR20100063052A (ko) 염증성 장 질환의 진단, 단계 구분 및 모니터링 방법
Jessen et al. Level of tumor necrosis factor production by stimulated blood mononuclear cells can be used to predict response of patients with inflammatory bowel diseases to infliximab
Klimczak et al. The diagnostic usefulness of fecal lactoferrin in the assessment of Crohn's disease activity
Ali et al. Study of albumin, c-reactive protein and calprotectin as non-invasive indicators for the diagnosis and differentiation of inflammatory bowel disease
ES2317327T3 (es) Procedimiento de diagnostico y tratamiento de la enfermedad de crohn.
KR20170115039A (ko) 가와사키병의 검사 방법 및 키트
US20230074127A1 (en) Test and in vitro diagnosis of irritable bowel syndrome
Toğrol et al. The significance of coeliac disease antibodies in patients with ankylosing spondylitis: a case-controlled study
Ghosh et al. P283 Bowel urgency in patients with moderate to severe ulcerative colitis: prevalence and correlation with clinical outcomes, biomarker levels, and health-related quality of life from U-ACHIEVE, a Phase 2b study of upadacitinib
CN114270191B (zh) 炎症性肠病诊断方法、诊断探针和诊断试剂盒
Waluga Biomarkers of irritable bowel syndrome
KR20130136964A (ko) 창자 감염성 병태의 생물학적 마커로서 hmgb1의 용도, 대변 샘플에서 그의 검출을 위한 비침습적 방법 및 키트
Giulia et al. Crohn’s disease (Primer)
US20220214357A1 (en) Method of determining the probability of inflammatory bowel disease in a subject being ulcerative colitis or crohn's disease
Saruta Positioning and Usefulness of Biomarkers in Inflammatory Bowel