MX2011011950A - Composiciones de dexmedetomidina sublinguales y metodos de uso de las mismas. - Google Patents

Composiciones de dexmedetomidina sublinguales y metodos de uso de las mismas.

Info

Publication number
MX2011011950A
MX2011011950A MX2011011950A MX2011011950A MX2011011950A MX 2011011950 A MX2011011950 A MX 2011011950A MX 2011011950 A MX2011011950 A MX 2011011950A MX 2011011950 A MX2011011950 A MX 2011011950A MX 2011011950 A MX2011011950 A MX 2011011950A
Authority
MX
Mexico
Prior art keywords
methods
dexmedetomidine compositions
sublingual
sublingual dexmedetomidine
compositions
Prior art date
Application number
MX2011011950A
Other languages
English (en)
Spanish (es)
Inventor
Geraldine Anne Henwood
Christopher Thomas Sharr
John Joseph Koleng Jr
Randall Jerome Mack
Original Assignee
Recro Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43085620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011011950(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recro Pharma Inc filed Critical Recro Pharma Inc
Publication of MX2011011950A publication Critical patent/MX2011011950A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0625—Mouth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2011011950A 2009-05-15 2010-05-17 Composiciones de dexmedetomidina sublinguales y metodos de uso de las mismas. MX2011011950A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17873009P 2009-05-15 2009-05-15
PCT/US2010/035136 WO2010132882A2 (en) 2009-05-15 2010-05-17 Sublingual dexmedetomidine compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2011011950A true MX2011011950A (es) 2012-02-21

Family

ID=43085620

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011950A MX2011011950A (es) 2009-05-15 2010-05-17 Composiciones de dexmedetomidina sublinguales y metodos de uso de las mismas.

Country Status (21)

Country Link
US (1) US20110021588A1 (enExample)
EP (2) EP2429521B1 (enExample)
JP (2) JP6172938B2 (enExample)
KR (1) KR101859486B1 (enExample)
CN (2) CN102639131A (enExample)
AU (1) AU2010248776B2 (enExample)
BR (1) BRPI1010567A2 (enExample)
CA (1) CA2762107A1 (enExample)
CL (1) CL2011002858A1 (enExample)
CO (1) CO6460767A2 (enExample)
CR (1) CR20110596A (enExample)
DO (1) DOP2011000354A (enExample)
EC (1) ECSP11011459A (enExample)
HN (1) HN2011003011A (enExample)
IL (1) IL216159A (enExample)
MX (1) MX2011011950A (enExample)
NZ (1) NZ596976A (enExample)
PE (1) PE20120713A1 (enExample)
RU (1) RU2572692C2 (enExample)
SG (1) SG175979A1 (enExample)
WO (1) WO2010132882A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
BR112014019171A8 (pt) * 2011-12-11 2017-07-11 Recro Pharma Inc Composições intranasais de dexdetomida e seus métodos de uso
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
CA2865593A1 (en) * 2012-02-27 2013-09-06 Eye Therapies Llc Compositions and methods for the treatment of migraine
LT2906213T (lt) * 2012-10-15 2018-02-26 Orion Corporation Baimės triukšmui palengvinimo veterinarinis būdas
EP2792352A1 (en) * 2013-04-16 2014-10-22 Laboratorios Del. Dr. Esteve, S.A. Alpha-2 adrenoreceptor and sigma receptor ligand combinations
US20150273215A1 (en) * 2014-03-26 2015-10-01 Pacesetter, Inc. Systems and methods for assessment of pain and other parameters during trial neurostimulation
TWI704933B (zh) 2013-10-07 2020-09-21 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
KR101831290B1 (ko) 2013-10-07 2018-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물
KR101891185B1 (ko) 2013-10-07 2018-08-24 테이코쿠 팔마 유에스에이, 인코포레이티드 비진정량의 덱스메데토미딘의 경피 전달을 위한 방법 및 조성물
RU2557882C1 (ru) * 2014-07-08 2015-07-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия" Министерства здравоохранения Российской Федерации (ГБОУ ВПО АГМА Минздрава России) Способ проведения премедикации при плановом хирургическом лечении
MA41689A (fr) * 2014-10-15 2017-08-22 Bioxcel Corp Prévention ou traitement de troubles du sommeil au moyen d'une formulation de dexmédétomidine
HRP20211310T1 (hr) * 2016-12-13 2021-11-26 Orion Corporation Deksmedetomidin ili medetomidin za upotrebu u liječenju anksioznosti koja je izazvana razdvajanjem kod životinja kućnih ljubimaca
DK3562486T3 (da) * 2016-12-31 2024-06-10 Bioxcel Therapeutics Inc Anvendelse af sublingual dexmedetomidin til behandling af agitation
CA3103431A1 (en) 2018-06-27 2020-01-02 Bioxcel Therapeutics, Inc. Film formulations containing dexmedetomidine and methods of producing them
US12472158B2 (en) 2019-02-27 2025-11-18 Vanderbilt University Methods of treating trigeminal nerve pain
CN116474218A (zh) * 2019-06-28 2023-07-25 四川普锐特药业有限公司 保持给药均一度的药物流体分配器及右美托咪定鼻喷器
MX2022000709A (es) * 2019-07-19 2022-05-19 Bioxcel Therapeutics Inc Regimenes de tratamiento con dexmedetomidina no sedante.
CN113827590A (zh) * 2020-06-08 2021-12-24 四川普锐特药业有限公司 右美托咪定在助眠药物制备中的应用
US20220031664A1 (en) * 2020-07-28 2022-02-03 Melt Pharmaceuticals, Inc. Pharmaceutical compositions comprising antiemetics and alpha-2-adrenergic receptor agonists and methods of using the same for anesthesiological applications
EP4583871A1 (en) * 2022-09-11 2025-07-16 BioXcel Therapeutics, Inc. Methods for treating agitation in community settings
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
CN118542852B (zh) * 2024-07-30 2024-10-01 山东则正医药技术有限公司 包含经口给药的右美托咪定舌下膜组合物及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.
DE69133584D1 (de) * 1990-12-05 2007-12-13 Gen Hospital Corp Vorrichtung zum Behandeln einen Lungengefässverengung und von Asthma
GB9111732D0 (en) * 1991-05-31 1991-07-24 Orion Yhtymae Oy The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
US5571840A (en) * 1993-06-22 1996-11-05 The Regents Of The University Of Michigan Method for treating central nervous system ischemia
US5713907A (en) * 1995-07-20 1998-02-03 Endotex Interventional Systems, Inc. Apparatus and method for dilating a lumen and for inserting an intraluminal graft
GB9520150D0 (en) 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030077227A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US6716867B1 (en) * 1998-04-01 2004-04-06 Orion Corporation Use of dexmedetomidine for ICU sedation
AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
US7001609B1 (en) * 1998-10-02 2006-02-21 Regents Of The University Of Minnesota Mucosal originated drug delivery systems and animal applications
CA2345808A1 (en) * 1998-10-02 2000-04-13 3M Innovative Properties Company Mucosal originated drug delivery systems and animal applications
GB9913677D0 (en) * 1999-06-11 1999-08-11 Imperial College Formulation
AUPR184500A0 (en) * 2000-12-01 2001-01-04 Drug Delivery Solutions Pty Ltd Dispensing device
US20030022926A1 (en) * 2001-05-07 2003-01-30 Lavand'homme Patricia Method for treating neuropathic pain and pharmaceutical preparation therefor
WO2002094238A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of anti-migraine compounds through an inhalation route
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
IL147921A0 (en) * 2002-01-31 2002-08-14 Abdulrazik Mohammad A method for treating central nervous system disorders by ocular dosing
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US20090117054A1 (en) * 2005-03-29 2009-05-07 University Of Kentucky Research Foundation Sublingual spray for the treatment of pain
RU2432950C2 (ru) * 2006-01-25 2011-11-10 Инсис Терапьютикс Инк. Подъязычный спрей на основе фентанила
EP1986642B1 (en) * 2006-02-13 2013-11-13 Orient Pharma (Samoa) Co, Ltd Combination of alpha-2 receptor agonist (clonidine) and an anti-muscarinic agent (oxybutynin) for the treatment of sialorrhoea
US20080021074A1 (en) * 2006-06-29 2008-01-24 Questcor Pharmaceuticals, Inc. Pharmaceutical Compositions and Related Methods of Treatment
CN101057830A (zh) * 2007-05-10 2007-10-24 北京天川军威医药技术开发有限公司 盐酸纳洛酮舌下喷雾给药系统或组合物及其制备方法

Also Published As

Publication number Publication date
JP2012526854A (ja) 2012-11-01
NZ596976A (en) 2014-05-30
RU2011151059A (ru) 2013-06-20
JP6172938B2 (ja) 2017-08-02
KR20120008058A (ko) 2012-01-25
RU2572692C2 (ru) 2016-01-20
CA2762107A1 (en) 2010-11-18
EP3305281A1 (en) 2018-04-11
IL216159A0 (en) 2012-01-31
EP2429521A4 (en) 2013-08-21
AU2010248776A1 (en) 2012-01-12
EP2429521B1 (en) 2017-10-18
WO2010132882A2 (en) 2010-11-18
IL216159A (en) 2015-10-29
ECSP11011459A (es) 2012-01-31
AU2010248776B2 (en) 2013-06-06
JP2016029055A (ja) 2016-03-03
PE20120713A1 (es) 2012-07-08
CN102639131A (zh) 2012-08-15
KR101859486B1 (ko) 2018-06-28
WO2010132882A8 (en) 2011-12-29
WO2010132882A3 (en) 2011-03-31
CL2011002858A1 (es) 2012-06-22
HN2011003011A (es) 2014-12-01
CR20110596A (es) 2012-03-26
EP2429521A2 (en) 2012-03-21
CO6460767A2 (es) 2012-06-15
BRPI1010567A2 (pt) 2016-03-15
US20110021588A1 (en) 2011-01-27
SG175979A1 (en) 2011-12-29
CN106511273A (zh) 2017-03-22
DOP2011000354A (es) 2012-07-15

Similar Documents

Publication Publication Date Title
MX2011011950A (es) Composiciones de dexmedetomidina sublinguales y metodos de uso de las mismas.
MX2012007933A (es) Composiciones de dexmedetomidina transdermicas topicas y metodos para su uso.
MX2011007930A (es) Conjugados de insulina cristalina.
MX2009012690A (es) Composiciones, metodos, dispositivos y sistemas para el cuidado bucal.
WO2009089494A3 (en) Pharmaceutical compositions
MX2011008450A (es) Agonistas y antagonistas del receptor s1p5, y metodos de uso de los mismos.
WO2012024620A3 (en) Autotaxin inhibitors and uses thereof
GB0920703D0 (en) Compositions containing satiogens and methods of use
MX2011003473A (es) Composiciones para el cuidado bucal.
MY160041A (en) Compositions and methods for treating parasitic infections
IN2012DN00624A (enExample)
WO2010009119A3 (en) Tooth whitening compositions and methods
EP2190408A4 (en) ANALGETIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHOD FOR THE TREATMENT, PREVENTION OR TREATMENT OF PAIN AND IGNITION
MY153948A (en) Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof
WO2009114703A3 (en) Combination therapy for the treatment of cancer
TN2012000059A1 (en) Compositions comprising tramadol and celecoxib in the treatment of pain
MX2011013032A (es) Inhibidores de fosfatidilinositol 3-cinasa.
MX2010002667A (es) Cianoaminoquinolonas y tetrazoloaminoquinolonas como inhibidores de gsk-3.
EP2249789A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF XEROSOMY
PH12012501389A1 (en) Hedgehog inhibitors
ZA201008160B (en) Compositions for the treatment of hair loss
HK1215391A1 (zh) 使用胎盘细胞外基质治疗口腔病变
MY157007A (en) Novel possibility of controlling giardiosis
MX2011013324A (es) Uso de derivados de oxindol sustituidos para el tratamiento y profilaxis del dolor.
PL2375912T3 (pl) Kompozycje i sposoby leczenia uczucia dyskomfortu gardła

Legal Events

Date Code Title Description
FG Grant or registration