MX2011009859A - Compuestos derivados de mentol y uso de los mismos como agentes activos orales y sistemicos. - Google Patents

Compuestos derivados de mentol y uso de los mismos como agentes activos orales y sistemicos.

Info

Publication number
MX2011009859A
MX2011009859A MX2011009859A MX2011009859A MX2011009859A MX 2011009859 A MX2011009859 A MX 2011009859A MX 2011009859 A MX2011009859 A MX 2011009859A MX 2011009859 A MX2011009859 A MX 2011009859A MX 2011009859 A MX2011009859 A MX 2011009859A
Authority
MX
Mexico
Prior art keywords
oral
menthol
derivative compounds
active agents
formula
Prior art date
Application number
MX2011009859A
Other languages
English (en)
Inventor
Tao Xu
Cortney Worrell
Davide Miksa
Yanan Hu
Ying Yang
Marsh M Trivedi
Chanda Macias
Original Assignee
Colgate Palmolive Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colgate Palmolive Co filed Critical Colgate Palmolive Co
Publication of MX2011009859A publication Critical patent/MX2011009859A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/411—Aromatic amines, i.e. where the amino group is directly linked to the aromatic nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

(ver fórmula (1)) La presente invención describe usos novedosos de compuestos específicos derivados de mentol de fórmula 1 y composiciones de los mismos, métodos para proporcionar beneficios de cuidado de salud oral y sistémica y métodos de regulación por aumento o regulación por disminución de metabolitos de enfermedades periodontales: fórmula 1, en donde X es un átomo de oxígeno o un radical NH; y R es un radical arilo o alifático no sustituido o sustituido. En algunas modalidades, los beneficios para el cuidado de la salud oral y sistémica incluyen beneficios contra la unión de biopelícula, anti-inflamación, antioxidantes, contra la pérdida ósea y antimicrobianos. En algunas modalidades, los metabolitos de enfermedad periodontal corresponden al estado oral sano y/o enfermo y permiten el diagnóstico diferencial de la salud oral.
MX2011009859A 2009-04-01 2009-04-01 Compuestos derivados de mentol y uso de los mismos como agentes activos orales y sistemicos. MX2011009859A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/039167 WO2010120275A2 (en) 2009-04-01 2009-04-01 Menthol-derivative compounds and use thereof as oral and systemic active agents

Publications (1)

Publication Number Publication Date
MX2011009859A true MX2011009859A (es) 2011-09-29

Family

ID=42983044

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011009859A MX2011009859A (es) 2009-04-01 2009-04-01 Compuestos derivados de mentol y uso de los mismos como agentes activos orales y sistemicos.

Country Status (15)

Country Link
US (1) US10426752B2 (es)
EP (1) EP2414571B1 (es)
JP (1) JP5550717B2 (es)
CN (1) CN102625866B (es)
AR (1) AR076181A1 (es)
AU (1) AU2009344336B2 (es)
BR (1) BRPI0924915A2 (es)
CA (1) CA2757425C (es)
MX (1) MX2011009859A (es)
MY (1) MY170956A (es)
RU (1) RU2492857C2 (es)
SG (1) SG173870A1 (es)
TW (1) TWI419682B (es)
WO (1) WO2010120275A2 (es)
ZA (1) ZA201107019B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201141536A (en) * 2009-12-21 2011-12-01 Colgate Palmolive Co Oral care compositions and methods
RU2490006C1 (ru) * 2012-07-18 2013-08-20 Илья Александрович Марков Фармацевтическая композиция в форме геля для профилактики и лечения заболеваний пародонта - дентоферон
EP3552597A1 (en) * 2012-08-07 2019-10-16 Symrise AG Cosmetic compositions
WO2014074806A1 (en) 2012-11-08 2014-05-15 Smith & Nephew, Inc-- Improved reattachment of detached cartilage to subchondral bone
US9827345B2 (en) 2012-11-08 2017-11-28 Smith & Nephew, Inc. Methods and compositions suitable for improved reattachment of detached cartilage to subchondral bone
JP2014222241A (ja) * 2014-07-10 2014-11-27 コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ 口の健康のための代謝産物およびその使用
KR102401971B1 (ko) * 2017-10-12 2022-05-27 제이알제이 주식회사 박하 추출물을 함유하는 바이오필름 형성 억제용 조성물
WO2023222213A1 (en) 2022-05-18 2023-11-23 Symrise Ag Antimicrobial mixtures
CN116350676B (zh) * 2023-04-06 2023-11-28 吴涛 一种利用干细胞外泌体促进牙周骨重建的药物

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US536844A (en) 1895-04-02 Padlock
US3538230A (en) 1966-12-05 1970-11-03 Lever Brothers Ltd Oral compositions containing silica xerogels as cleaning and polishing agents
US4358437A (en) 1978-11-29 1982-11-09 Beecham Group Limited Compositions
US5288480A (en) * 1987-01-30 1994-02-22 Colgate-Palmolive Co. Antiplaque antibacterial oral composition
US6214320B1 (en) 1990-10-09 2001-04-10 Colgate-Palmolive Company Oral compositions containing anticalculus and antiplaque agents
GB9117140D0 (en) 1991-08-08 1991-09-25 Unilever Plc Treatment of periodontitis
DE4226043A1 (de) 1992-08-06 1994-02-10 Haarmann & Reimer Gmbh Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen
WO1995013094A1 (en) 1993-11-10 1995-05-18 Bristol-Myers Squibb Company Treatment of bacterially-induced inflammatory diseases
US5578295A (en) 1995-04-28 1996-11-26 The Procter & Gamble Company Oral care compositions comprising certain substituted diphenyl ethers
JP2000512285A (ja) 1996-06-12 2000-09-19 ヘンケル・コマンディットゲゼルシャフト・アウフ・アクチエン 化粧品および／または薬剤製剤
US5945088A (en) * 1997-03-31 1999-08-31 Pfizer Inc Taste masking of phenolics using citrus flavors
US6261540B1 (en) 1997-10-22 2001-07-17 Warner-Lambert Company Cyclodextrins and hydrogen peroxide in dental products
FR2794457B1 (fr) 1999-06-01 2001-08-10 Oreal Derives carbonates de retinol, procede de preparation et utilisations
US20050245494A1 (en) 1999-07-01 2005-11-03 40 J's Llc Methods to treat one or all of the defined etiologies of female sexual dysfunction
JP2003518627A (ja) 1999-12-03 2003-06-10 バクスター・インターナショナル・インコーポレイテッド 自動イムノアッセイシステムを用いる使用のための発熱性試験
GB0001704D0 (en) 2000-01-25 2000-03-15 Glaxo Group Ltd Protein
CA2443806A1 (en) 2000-04-14 2002-10-25 Metabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
US7329489B2 (en) 2000-04-14 2008-02-12 Matabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
US6500409B1 (en) 2000-05-10 2002-12-31 Colgate Palmolive Company Synergistic antiplaque/antigingivitis oral composition
US6372795B1 (en) * 2000-06-30 2002-04-16 Unilever Home And Personal Care Usa, A Division Of Conopco, Inc. Cosmetic compositions containing substituted amide derivatives
DE10059584A1 (de) 2000-11-30 2002-06-06 Beiersdorf Ag Kosmetische oder dermatologische getränkte Tücher
DE10140443A1 (de) 2001-08-17 2003-02-27 Haarmann & Reimer Gmbh 2-(3,4-Dihydroxyphenyl)ethyl-substituierte Kohlensäurederivate und deren Verwendung
DE10226494A1 (de) * 2002-06-14 2004-01-08 Lts Lohmann Therapie-Systeme Ag Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen
GB0214342D0 (en) * 2002-06-21 2002-07-31 Givaudan Sa Insect repellents
US6916463B2 (en) * 2002-09-24 2005-07-12 The Procter & Gamble Company Oral products having an aesthetic layer
US7005225B2 (en) 2002-11-12 2006-02-28 Samsung Electronics Company Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications
EP1599212A4 (en) 2003-02-14 2006-02-08 Combinatorx Inc POLYTHERAPY FOR THE TREATMENT OF IMMUNO-INFLAMMATORY DISORDERS
EP1466949A1 (en) 2003-04-10 2004-10-13 Symrise GmbH & Co. KG Non-toxic coating composition, methods of use thereof and articles protected from attachment of biofouling organisms
GB2401865A (en) 2003-05-22 2004-11-24 Givaudan Sa Antibacterial and antifungal glycerol monocarbonates
DE10341699A1 (de) * 2003-09-10 2005-04-28 Symrise Gmbh & Co Kg Verfahren zur Herstellung unsymmetrischer Kohlensäureester
EP1697389A4 (en) 2003-10-24 2008-12-24 Eisai R&D Man Co Ltd COMPOUNDS AND METHODS FOR TREATING ILLNESS AND SUFFERING TOLL-LIKE RECEPTOR 2 RELATED DISORDERS
PT1701978E (pt) 2003-12-03 2009-03-03 Whitehead Biomedical Inst Utilização de caderina-t solúvel no tratamento de distúrbios metabólicos
FI20040572A0 (fi) 2004-04-23 2004-04-23 Ctt Cancer Targeting Tech Oy Matriisi-metalloproteinaasin aktiviteetin inhibiittorit
WO2006034495A2 (en) * 2004-09-23 2006-03-30 Matias Jonathan R Methods of using menthol propyleneglycol-carbonate and analogs thereof for producing anti-inflammatory and anti-angiogenic effects
EP1919284A1 (en) * 2004-09-24 2008-05-14 Symrise GmbH & Co. KG Use of isoeugenol methyl ether as an agent against bad breath
US20060141421A1 (en) 2004-12-28 2006-06-29 Kimberly-Clark Worldwide, Inc. System and method for detecting substances related to oral health
WO2006074450A2 (en) 2005-01-07 2006-07-13 President And Fellows Of Harvard College Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases
BRPI0604323B1 (pt) * 2005-10-21 2016-07-26 Givaudan Sa composto de redução de mau cheiro, sua composição e produto, método de formação do referido produto e método de redução de mau cheiro
ES2431291T3 (es) 2006-01-10 2013-11-25 Colgate-Palmolive Company Métodos para modular receptores de superficie celular para prevenir o reducir la inflamación
US20080161394A1 (en) 2006-11-23 2008-07-03 Jean-Yves Fouron Cosmetic composition comprising at least one volatile carbonic acid ester
WO2008093072A2 (en) 2007-01-29 2008-08-07 Paul Webb Topical composition against contact dermatitis due to water
US8333981B2 (en) 2007-10-09 2012-12-18 Humco Holding Group, Inc. Antifungal treatment of nails
EP2307357A1 (en) * 2008-05-30 2011-04-13 Symrise AG L-menthyl-n-(2-hydroxyphenyl)carbamate

Also Published As

Publication number Publication date
ZA201107019B (en) 2014-09-25
AU2009344336B2 (en) 2013-07-18
EP2414571A2 (en) 2012-02-08
AU2009344336A1 (en) 2011-09-22
CN102625866B (zh) 2015-08-19
US20120014884A1 (en) 2012-01-19
CN102625866A (zh) 2012-08-01
JP5550717B2 (ja) 2014-07-16
AR076181A1 (es) 2011-05-26
MY170956A (en) 2019-09-20
CA2757425A1 (en) 2010-10-21
EP2414571B1 (en) 2017-06-07
WO2010120275A3 (en) 2012-04-12
SG173870A1 (en) 2011-09-29
JP2012522772A (ja) 2012-09-27
TWI419682B (zh) 2013-12-21
TW201102058A (en) 2011-01-16
RU2492857C2 (ru) 2013-09-20
CA2757425C (en) 2015-06-30
BRPI0924915A2 (pt) 2015-07-07
WO2010120275A2 (en) 2010-10-21
US10426752B2 (en) 2019-10-01

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