MX2011004719A - Virus sincitial respiratorio vivo atenuado. - Google Patents
Virus sincitial respiratorio vivo atenuado.Info
- Publication number
- MX2011004719A MX2011004719A MX2011004719A MX2011004719A MX2011004719A MX 2011004719 A MX2011004719 A MX 2011004719A MX 2011004719 A MX2011004719 A MX 2011004719A MX 2011004719 A MX2011004719 A MX 2011004719A MX 2011004719 A MX2011004719 A MX 2011004719A
- Authority
- MX
- Mexico
- Prior art keywords
- gene
- nucleotide
- protein encoded
- amino acid
- mutation
- Prior art date
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18561—Methods of inactivation or attenuation
- C12N2760/18564—Methods of inactivation or attenuation by serial passage
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Applications Claiming Priority (2)
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| US19832708P | 2008-11-05 | 2008-11-05 | |
| PCT/US2009/063024 WO2010053883A1 (en) | 2008-11-05 | 2009-11-03 | Live, attentuated respiratory syncytial virus |
Publications (1)
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| MX2011004719A true MX2011004719A (es) | 2011-05-31 |
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| MX2011004719A MX2011004719A (es) | 2008-11-05 | 2009-11-03 | Virus sincitial respiratorio vivo atenuado. |
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| JP (2) | JP5016731B2 (enExample) |
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| US9011876B2 (en) * | 2008-11-05 | 2015-04-21 | Merck Sharp & Dohme Corp. | Live, attenuated respiratory syncytial virus |
| US20140242669A1 (en) * | 2011-08-18 | 2014-08-28 | Ycine Llc | Production of infectious rna viruses in yeast |
| WO2013031827A1 (ja) | 2011-08-29 | 2013-03-07 | 国立大学法人徳島大学 | Rsv粘膜ワクチン |
| EP4190895A1 (en) * | 2013-02-08 | 2023-06-07 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Attenuation of human respiratory syncytial virus by genome scale codon-pair deoptimization |
| ES2854673T3 (es) * | 2013-03-14 | 2021-09-22 | Univ Emory | VSR recombinante con mutaciones silenciosas, vacunas y métodos relacionados con ello |
| CA2927431C (en) | 2013-10-16 | 2023-10-03 | Merck Sharp & Dohme Corp. | Method of microwave vacuum drying spherical-shaped pellets of biological materials |
| CA2926696A1 (en) | 2013-10-16 | 2015-04-23 | Merck Sharp & Dohme Corp | Thermostable respiratory synctial virus (rsv) vaccine compositions |
| WO2017030997A1 (en) * | 2015-08-14 | 2017-02-23 | Research Institute At Nationwide Children's Hospital | Respiratory syncytial virus having altered ns1 protein function and related materials and methods |
| EP3368547A4 (en) | 2015-10-29 | 2019-06-05 | Emory University | CHIMERIC RSV, IMMUNOGENIC COMPOSITIONS AND METHOD FOR USE THEREOF |
| AU2017332789B2 (en) | 2016-09-23 | 2021-05-27 | Codagenix, Inc. | Vaccine candidates for human respiratory syncytial virus (RSV) having attenuated phenotypes |
| TWI761453B (zh) | 2017-03-01 | 2022-04-21 | 英商梅迪繆思有限公司 | 抗rsv單株抗體配製物 |
| CA3075990A1 (en) * | 2017-09-15 | 2019-03-21 | Ohio State Innovation Foundation | Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (rsv) infections |
| TW202535439A (zh) * | 2023-11-17 | 2025-09-16 | 美商賽諾菲巴斯德公司 | 海藻糖疫苗調配物 |
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| AU2438597A (en) | 1996-04-04 | 1997-10-29 | Regents Of The University Of Michigan, The | Attenuated respiratory syncytial virus |
| IL138681A0 (en) | 1998-03-26 | 2001-10-31 | American Cyanamid Co | Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup b |
| KR100905450B1 (ko) | 1999-07-09 | 2009-07-02 | 더 가버먼트 오브 더 유나이티드 스테이츠 오브 어메리카 애즈 리프리젠티드 바이 더 디파트먼트 오브 헬스 앤 휴먼 서비씨즈 | 약독화된 인간-소 키메릭 호흡기 신시티움 바이러스백신의 제조 방법 |
| AU2003295339B2 (en) | 2002-09-27 | 2009-03-26 | Medimmune, Llc | Functional mutations in respiratory syncytial virus |
| ATE469170T1 (de) * | 2003-03-28 | 2010-06-15 | Medimmune Llc | Zusammensetzungen und verfahren mit dem respiratory syncytial virus untergruppe b stamm 9320 |
| CN101646768A (zh) * | 2007-02-07 | 2010-02-10 | 生物载体株式会社 | 减毒负链rna病毒 |
| US9011876B2 (en) * | 2008-11-05 | 2015-04-21 | Merck Sharp & Dohme Corp. | Live, attenuated respiratory syncytial virus |
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2009
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2011
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| BRPI0921424A2 (pt) | 2016-01-05 |
| MA32878B1 (fr) | 2011-12-01 |
| CL2011000999A1 (es) | 2012-07-20 |
| AU2009311287A1 (en) | 2010-05-14 |
| PE20110394A1 (es) | 2011-06-22 |
| ECSP11011033A (es) | 2011-12-30 |
| ZA201103259B (en) | 2012-01-25 |
| JP5743794B2 (ja) | 2015-07-01 |
| AU2009311287B2 (en) | 2013-02-07 |
| CO6362047A2 (es) | 2012-01-20 |
| AU2009311287C1 (en) | 2015-02-19 |
| TN2011000182A1 (en) | 2012-12-17 |
| US20110212130A1 (en) | 2011-09-01 |
| IL212437A0 (en) | 2011-06-30 |
| EP2346990B1 (en) | 2016-01-06 |
| KR20110063863A (ko) | 2011-06-14 |
| CN102272295A (zh) | 2011-12-07 |
| JP2012507302A (ja) | 2012-03-29 |
| EP2346990A1 (en) | 2011-07-27 |
| JP5016731B2 (ja) | 2012-09-05 |
| WO2010053883A1 (en) | 2010-05-14 |
| US9011876B2 (en) | 2015-04-21 |
| RU2011122615A (ru) | 2012-12-20 |
| JP2011250798A (ja) | 2011-12-15 |
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