MX2010008923A - Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-dia mina y su uso como antipsicotico. - Google Patents

Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-dia mina y su uso como antipsicotico.

Info

Publication number
MX2010008923A
MX2010008923A MX2010008923A MX2010008923A MX2010008923A MX 2010008923 A MX2010008923 A MX 2010008923A MX 2010008923 A MX2010008923 A MX 2010008923A MX 2010008923 A MX2010008923 A MX 2010008923A MX 2010008923 A MX2010008923 A MX 2010008923A
Authority
MX
Mexico
Prior art keywords
compound
indeno
thiazole
dihydro
diamine
Prior art date
Application number
MX2010008923A
Other languages
English (en)
Inventor
Gary Steelman
Rebecca Urbanek
William C Blackwell Iii
James Hulsizer
Jianwei Liu
Dan Widzowski
Ye Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2010008923A publication Critical patent/MX2010008923A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto de la fórmula I y sales farmaceuticamente aceptables del mismo: (R)-N*6*etil-6,7-dihidro-5H-indeno(5,6-d)tiazol-2,6-diamina. Esta invención también se refiere a métodos para elaborar, métodos para usar, y composiciones farmacéuticas y comprenden el compuesto de la fórmula I y sales del mismo.
MX2010008923A 2008-02-21 2009-02-20 Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-dia mina y su uso como antipsicotico. MX2010008923A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3033208P 2008-02-21 2008-02-21
PCT/SE2009/050188 WO2009105026A1 (en) 2008-02-21 2009-02-20 Compound (r) -n*6*-ethyl-6, 7-dihydro-5h-indeno (5, 6- d) thiazole-2, 6-diamine and the use as antipsychotics

Publications (1)

Publication Number Publication Date
MX2010008923A true MX2010008923A (es) 2010-09-07

Family

ID=40985770

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010008923A MX2010008923A (es) 2008-02-21 2009-02-20 Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-dia mina y su uso como antipsicotico.

Country Status (24)

Country Link
US (1) US20090215841A1 (es)
EP (1) EP2254876A4 (es)
JP (1) JP2011512407A (es)
KR (1) KR20100122487A (es)
CN (1) CN101952266A (es)
AR (1) AR070618A1 (es)
AU (1) AU2009215920A1 (es)
BR (1) BRPI0907158A2 (es)
CA (1) CA2716215A1 (es)
CL (1) CL2009000392A1 (es)
CO (1) CO6300849A2 (es)
CR (1) CR11639A (es)
DO (1) DOP2010000257A (es)
EA (1) EA201001095A1 (es)
EC (1) ECSP10010412A (es)
IL (1) IL206817A0 (es)
MX (1) MX2010008923A (es)
NI (1) NI201000141A (es)
PE (1) PE20091566A1 (es)
SA (1) SA109300120B1 (es)
TW (1) TW200940516A (es)
UY (1) UY31668A1 (es)
WO (1) WO2009105026A1 (es)
ZA (1) ZA201004800B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017219808A1 (zh) * 2016-06-21 2017-12-28 浙江柏拉阿图医药科技有限公司 丙型肝炎病毒抑制剂及应用
CN109134600B (zh) * 2017-06-19 2021-07-20 杭州国谋生物科技有限公司 作为丙型肝炎抑制剂的烷基及杂环化合物及其在药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802360D0 (sv) * 1998-07-01 1998-07-01 Wikstroem Hakan Vilhelm New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin
WO2005084205A2 (en) * 2004-02-27 2005-09-15 Teva Pharmaceutical Industries, Ltd. Diamino thiazoloindan derivatives and their use

Also Published As

Publication number Publication date
US20090215841A1 (en) 2009-08-27
EA201001095A1 (ru) 2011-04-29
CL2009000392A1 (es) 2010-09-24
EP2254876A1 (en) 2010-12-01
ZA201004800B (en) 2012-06-27
BRPI0907158A2 (pt) 2015-07-07
TW200940516A (en) 2009-10-01
IL206817A0 (en) 2010-12-30
JP2011512407A (ja) 2011-04-21
KR20100122487A (ko) 2010-11-22
AR070618A1 (es) 2010-04-21
PE20091566A1 (es) 2009-11-06
CA2716215A1 (en) 2009-08-27
CN101952266A (zh) 2011-01-19
DOP2010000257A (es) 2010-10-31
EP2254876A4 (en) 2012-10-31
NI201000141A (es) 2011-03-24
SA109300120B1 (ar) 2011-10-08
ECSP10010412A (es) 2010-09-30
AU2009215920A1 (en) 2009-08-27
CR11639A (es) 2010-10-05
UY31668A1 (es) 2009-09-30
CO6300849A2 (es) 2011-07-21
WO2009105026A1 (en) 2009-08-27

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Legal Events

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