MX2010006972A - Moduladores selectivos de receptores de andrógenos (sarm) y usos de los mismos. - Google Patents

Moduladores selectivos de receptores de andrógenos (sarm) y usos de los mismos.

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Publication number
MX2010006972A
MX2010006972A MX2010006972A MX2010006972A MX2010006972A MX 2010006972 A MX2010006972 A MX 2010006972A MX 2010006972 A MX2010006972 A MX 2010006972A MX 2010006972 A MX2010006972 A MX 2010006972A MX 2010006972 A MX2010006972 A MX 2010006972A
Authority
MX
Mexico
Prior art keywords
sarms
androgen receptor
receptor modulators
selective androgen
compounds
Prior art date
Application number
MX2010006972A
Other languages
English (en)
Inventor
Lin Zhi
Original Assignee
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ligand Pharm Inc filed Critical Ligand Pharm Inc
Publication of MX2010006972A publication Critical patent/MX2010006972A/es

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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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Abstract

Se proporcionan en la presente compuestos de las Fórmulas I a II que se unen a receptores de andrógeno y/o modulan la actividad de los receptores de andrógeno; y métodos para producir y usar estos compuestos. También proporcionan composiciones que incluyen estos compuestos y métodos para producir y usar estas composiciones. (ver fórmulas).
MX2010006972A 2007-12-21 2008-12-12 Moduladores selectivos de receptores de andrógenos (sarm) y usos de los mismos. MX2010006972A (es)

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