MX2010005520A - Peptidos con capacidad para unirse a escurfina y aplicaciones. - Google Patents
Peptidos con capacidad para unirse a escurfina y aplicaciones.Info
- Publication number
- MX2010005520A MX2010005520A MX2010005520A MX2010005520A MX2010005520A MX 2010005520 A MX2010005520 A MX 2010005520A MX 2010005520 A MX2010005520 A MX 2010005520A MX 2010005520 A MX2010005520 A MX 2010005520A MX 2010005520 A MX2010005520 A MX 2010005520A
- Authority
- MX
- Mexico
- Prior art keywords
- peptides
- scurfin
- bind
- regulating
- activity
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102100027581 Forkhead box protein P3 Human genes 0.000 title abstract 2
- 101710088098 Forkhead box protein P3 Proteins 0.000 title abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Péptidos de fórmula general (I), donde X está ausente, o bien, X está presente y es X14 o X14-X15, donde X14 y X15, independientemente entre sí, representan un aminoácido; sus variantes y fragmentos funcionales, y sus sales farmacéuticamente aceptables, tienen la capacidad de unirse a la escurfina e inhibir su actividad biológica, por lo que pueden regular o bloquear la actividad de los linfocitos T reguladores (Treg). De aplicación en el tratamiento de enfermedades infecciosas y neoplásicas. Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe-Phe-X .
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200703052A ES2328776B1 (es) | 2007-11-19 | 2007-11-19 | Peptidos con capacidad para unirse a escurfina y aplicaciones. |
PCT/ES2008/000716 WO2009065982A1 (es) | 2007-11-19 | 2008-11-14 | Péptidos con capacidad para unirse a escurfina y aplicaciones |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010005520A true MX2010005520A (es) | 2010-09-28 |
Family
ID=40409793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010005520A MX2010005520A (es) | 2007-11-19 | 2008-11-14 | Peptidos con capacidad para unirse a escurfina y aplicaciones. |
Country Status (11)
Country | Link |
---|---|
US (1) | US8524860B2 (es) |
EP (1) | EP2223998B1 (es) |
JP (1) | JP5385910B2 (es) |
CN (1) | CN101903514B (es) |
AU (1) | AU2008327792B2 (es) |
BR (1) | BRPI0819311A2 (es) |
CA (1) | CA2706201A1 (es) |
ES (1) | ES2328776B1 (es) |
MX (1) | MX2010005520A (es) |
RU (1) | RU2502741C2 (es) |
WO (1) | WO2009065982A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8080518B2 (en) * | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
HUE046640T2 (hu) | 2009-06-10 | 2020-03-30 | Nono Inc | TAT-internalizáló peptidhez kapcsolt hatóanyag együttes beadása egy hízósejt degranuláció-inhibitorral |
EP3107552B1 (en) * | 2014-02-21 | 2018-03-28 | Cellectis | Method for in situ inhibition of regulatory t cells |
ES2665543B1 (es) * | 2016-10-26 | 2019-02-12 | Fundacion Para La Investig Medica Aplicada | Péptidos de unión a FOXP3 y usos de los mismos |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5698015A (en) * | 1995-05-19 | 1997-12-16 | Nikko Company | Conductor paste for plugging through-holes in ceramic circuit boards and a ceramic circuit board having this conductor paste |
AU1818299A (en) * | 1997-12-10 | 1999-06-28 | Washington University | Anti-pathogen system and methods of use thereof |
US6414129B1 (en) * | 1998-08-11 | 2002-07-02 | Darwin Discovery Ltd. | Identification of the gene causing the mouse scurfy phenotype and its human ortholog |
WO2001059115A2 (en) * | 2000-02-09 | 2001-08-16 | Agensys, Inc. | 83p5g4: a tissue specific protein highly expressed in prostate cancer |
US20030191073A1 (en) * | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
EP1446500B1 (en) * | 2001-05-08 | 2008-08-20 | Darwin Molecular Corporation | A method for regulating immune function in primates using the foxp3 protein |
WO2006044864A2 (en) * | 2004-10-19 | 2006-04-27 | Duke University | Vaccine adjuvant |
WO2007084775A2 (en) * | 2006-01-20 | 2007-07-26 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
-
2007
- 2007-11-19 ES ES200703052A patent/ES2328776B1/es not_active Expired - Fee Related
-
2008
- 2008-11-14 WO PCT/ES2008/000716 patent/WO2009065982A1/es active Application Filing
- 2008-11-14 JP JP2010534507A patent/JP5385910B2/ja not_active Expired - Fee Related
- 2008-11-14 US US12/743,616 patent/US8524860B2/en not_active Expired - Fee Related
- 2008-11-14 EP EP08852484.8A patent/EP2223998B1/en active Active
- 2008-11-14 MX MX2010005520A patent/MX2010005520A/es active IP Right Grant
- 2008-11-14 CA CA2706201A patent/CA2706201A1/en not_active Abandoned
- 2008-11-14 AU AU2008327792A patent/AU2008327792B2/en not_active Ceased
- 2008-11-14 RU RU2010125199/10A patent/RU2502741C2/ru not_active IP Right Cessation
- 2008-11-14 CN CN2008801217329A patent/CN101903514B/zh not_active Expired - Fee Related
- 2008-11-14 BR BRPI0819311-8A patent/BRPI0819311A2/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BRPI0819311A2 (pt) | 2015-06-16 |
AU2008327792A1 (en) | 2009-05-28 |
ES2328776A1 (es) | 2009-11-17 |
RU2502741C2 (ru) | 2013-12-27 |
ES2328776B1 (es) | 2010-07-06 |
CN101903514A (zh) | 2010-12-01 |
AU2008327792B2 (en) | 2014-04-24 |
US8524860B2 (en) | 2013-09-03 |
EP2223998A1 (en) | 2010-09-01 |
EP2223998B1 (en) | 2015-05-13 |
JP2011504108A (ja) | 2011-02-03 |
JP5385910B2 (ja) | 2014-01-08 |
WO2009065982A1 (es) | 2009-05-28 |
CA2706201A1 (en) | 2009-05-28 |
US20100267623A1 (en) | 2010-10-21 |
RU2010125199A (ru) | 2011-12-27 |
CN101903514B (zh) | 2013-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |