MX2010003139A - Agentes terapeuticos para la enfermedad de injerto contra hospedero que comprenden un inhibidor del receptor de interleucina 6 como ingrediente activo. - Google Patents
Agentes terapeuticos para la enfermedad de injerto contra hospedero que comprenden un inhibidor del receptor de interleucina 6 como ingrediente activo.Info
- Publication number
- MX2010003139A MX2010003139A MX2010003139A MX2010003139A MX2010003139A MX 2010003139 A MX2010003139 A MX 2010003139A MX 2010003139 A MX2010003139 A MX 2010003139A MX 2010003139 A MX2010003139 A MX 2010003139A MX 2010003139 A MX2010003139 A MX 2010003139A
- Authority
- MX
- Mexico
- Prior art keywords
- remedy
- interleukin
- graft
- versus
- active ingredient
- Prior art date
Links
- 208000009329 Graft vs Host Disease Diseases 0.000 title abstract 4
- 208000024908 graft versus host disease Diseases 0.000 title abstract 4
- 239000004480 active ingredient Substances 0.000 title abstract 2
- 102000010781 Interleukin-6 Receptors Human genes 0.000 title 1
- 108010038501 Interleukin-6 Receptors Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102000004889 Interleukin-6 Human genes 0.000 abstract 2
- 108090001005 Interleukin-6 Proteins 0.000 abstract 2
- 229940100601 interleukin-6 Drugs 0.000 abstract 2
- 108091006082 receptor inhibitors Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invenci?n proporciona un novedoso agente terap?utico para la enfermedad de injerto contra hospedero (GVHD); un agente terap?utico para la enfermedad de injerto contra hospedero (GVHD), que comprende un inhibidor del receptor de interleucina 6 (IL-6) como un ingrediente activo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007258810 | 2007-10-02 | ||
PCT/JP2008/067835 WO2009044774A1 (ja) | 2007-10-02 | 2008-10-01 | インターロイキン6受容体阻害剤を有効成分とする移植片対宿主病治療剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010003139A true MX2010003139A (es) | 2010-04-07 |
Family
ID=40526199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010003139A MX2010003139A (es) | 2007-10-02 | 2008-10-01 | Agentes terapeuticos para la enfermedad de injerto contra hospedero que comprenden un inhibidor del receptor de interleucina 6 como ingrediente activo. |
Country Status (13)
Country | Link |
---|---|
US (1) | US8529895B2 (es) |
EP (1) | EP2196220B1 (es) |
JP (1) | JP5264752B2 (es) |
KR (1) | KR101601986B1 (es) |
CN (1) | CN101815532B (es) |
AU (1) | AU2008308163B2 (es) |
BR (2) | BR122019021238B8 (es) |
CA (1) | CA2701155C (es) |
HK (1) | HK1145288A1 (es) |
MX (1) | MX2010003139A (es) |
RU (1) | RU2490025C2 (es) |
TW (1) | TWI468173B (es) |
WO (1) | WO2009044774A1 (es) |
Families Citing this family (32)
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JPH10324639A (ja) | 1997-03-21 | 1998-12-08 | Chugai Pharmaceut Co Ltd | Il−6アンタゴニストを有効成分として含有する感作t細胞関与疾患の予防・治療剤 |
UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
AU2003211991B2 (en) * | 2002-02-14 | 2008-08-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody-containing solution formulations |
GB2401040A (en) * | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
US8398980B2 (en) * | 2004-03-24 | 2013-03-19 | Chugai Seiyaku Kabushiki Kaisha | Subtypes of humanized antibody against interleuken-6 receptor |
WO2007114319A1 (ja) | 2006-03-31 | 2007-10-11 | Chugai Seiyaku Kabushiki Kaisha | 抗体の血中動態を制御する方法 |
CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
WO2009041613A1 (ja) | 2007-09-26 | 2009-04-02 | Chugai Seiyaku Kabushiki Kaisha | 抗体定常領域改変体 |
PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
LT2708559T (lt) | 2008-04-11 | 2018-06-11 | Chugai Seiyaku Kabushiki Kaisha | Antigeną surišanti molekulė, galinti pakartotinai prisijungti prie dviejų ar daugiau antigeno molekulių |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
KR102071834B1 (ko) | 2009-10-26 | 2020-01-30 | 에프. 호프만-라 로슈 아게 | 글리코실화된 면역글로불린의 제조 방법 |
JP2013541594A (ja) | 2010-11-08 | 2013-11-14 | ジェネンテック, インコーポレイテッド | 皮下投与される抗il−6受容体抗体 |
EP2647706B1 (en) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
US10782290B2 (en) | 2013-06-11 | 2020-09-22 | National Center Of Neurology And Psychiatry | Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (RRMS) patient, and method for determining applicability of novel therapy |
BR112015032960B1 (pt) | 2013-07-04 | 2021-01-05 | F. Hoffmann-La Roche Ag | imunoensaio suprimido por interferência para detectar anticorpos anti-fármaco em amostras de soro |
KR20170058432A (ko) | 2014-10-10 | 2017-05-26 | 화이자 인코포레이티드 | 상승 효과적 아우리스타틴 조합 |
BR112017014067B1 (pt) | 2015-02-27 | 2021-01-12 | Chugai Seiyaku Kabushiki Kaisha | usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6 |
PL3299810T3 (pl) | 2015-05-19 | 2021-12-13 | National Center Of Neurology And Psychiatry | Sposób określania zastosowania nowej terapii u pacjentów ze stwardnieniem rozsianym (sm) |
WO2017147169A1 (en) | 2016-02-22 | 2017-08-31 | Ohio State Innovation Foundation | Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin a analogues or metabolites, and estradiol metabolites |
CA3045475A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device |
WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
AU2018234844B2 (en) | 2017-03-17 | 2024-01-25 | Ohio State Innovation Foundation | Nanoparticles for delivery of chemopreventive agents |
EP4108183A1 (en) | 2017-03-30 | 2022-12-28 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | 国立研究開発法人国立精神・神経医療研究センター | Il-6及び好中球の関連する疾患の治療効果の予測及び判定方法 |
WO2019078344A1 (ja) | 2017-10-20 | 2019-04-25 | 学校法人兵庫医科大学 | 抗il-6受容体抗体を含有する術後の癒着を抑制するための医薬組成物 |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
WO2019246271A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
JP2022527972A (ja) | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
US20240200085A1 (en) | 2022-12-15 | 2024-06-20 | Aarhus Universitet | Synthetic activation of multimeric transmembrane receptors |
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AR057582A1 (es) * | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
BRPI0806812B8 (pt) | 2007-01-23 | 2021-09-14 | Chugai Pharmaceutical Co Ltd | Agente para suprimir reação de rejeição crônica e uso de um inibidor de il-6 |
-
2008
- 2008-10-01 BR BR122019021238A patent/BR122019021238B8/pt active IP Right Grant
- 2008-10-01 EP EP08836642.2A patent/EP2196220B1/en active Active
- 2008-10-01 WO PCT/JP2008/067835 patent/WO2009044774A1/ja active Application Filing
- 2008-10-01 MX MX2010003139A patent/MX2010003139A/es active IP Right Grant
- 2008-10-01 US US12/733,951 patent/US8529895B2/en active Active
- 2008-10-01 CN CN2008801100103A patent/CN101815532B/zh active Active
- 2008-10-01 RU RU2010117171/15A patent/RU2490025C2/ru active
- 2008-10-01 AU AU2008308163A patent/AU2008308163B2/en active Active
- 2008-10-01 BR BRPI0817482A patent/BRPI0817482B8/pt active IP Right Grant
- 2008-10-01 CA CA2701155A patent/CA2701155C/en active Active
- 2008-10-01 JP JP2009536069A patent/JP5264752B2/ja active Active
- 2008-10-01 KR KR1020107009597A patent/KR101601986B1/ko active IP Right Grant
- 2008-10-02 TW TW97137932A patent/TWI468173B/zh active
-
2010
- 2010-12-16 HK HK10111739.1A patent/HK1145288A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP2196220A4 (en) | 2011-12-21 |
US8529895B2 (en) | 2013-09-10 |
EP2196220A1 (en) | 2010-06-16 |
CN101815532A (zh) | 2010-08-25 |
AU2008308163B2 (en) | 2013-03-21 |
BR122019021238B8 (pt) | 2021-07-27 |
RU2010117171A (ru) | 2011-11-10 |
RU2490025C2 (ru) | 2013-08-20 |
WO2009044774A1 (ja) | 2009-04-09 |
TWI468173B (zh) | 2015-01-11 |
BRPI0817482A2 (pt) | 2015-09-29 |
KR101601986B1 (ko) | 2016-03-17 |
HK1145288A1 (en) | 2011-04-15 |
BRPI0817482B8 (pt) | 2021-05-25 |
US20100255007A1 (en) | 2010-10-07 |
BRPI0817482B1 (pt) | 2020-01-14 |
CN101815532B (zh) | 2012-08-15 |
BR122019021238B1 (pt) | 2021-02-23 |
JP5264752B2 (ja) | 2013-08-14 |
KR20100075591A (ko) | 2010-07-02 |
CA2701155A1 (en) | 2009-04-09 |
AU2008308163A1 (en) | 2009-04-09 |
EP2196220B1 (en) | 2014-12-03 |
CA2701155C (en) | 2016-11-22 |
JPWO2009044774A1 (ja) | 2011-02-10 |
TW200932262A (en) | 2009-08-01 |
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