MX2010001978A - Estereoisomero de acetamida. - Google Patents
Estereoisomero de acetamida.Info
- Publication number
- MX2010001978A MX2010001978A MX2010001978A MX2010001978A MX2010001978A MX 2010001978 A MX2010001978 A MX 2010001978A MX 2010001978 A MX2010001978 A MX 2010001978A MX 2010001978 A MX2010001978 A MX 2010001978A MX 2010001978 A MX2010001978 A MX 2010001978A
- Authority
- MX
- Mexico
- Prior art keywords
- stereoisomer
- acetamide
- acetamide stereoisomer
- bronchodilator
- stable
- Prior art date
Links
- 150000003869 acetamides Chemical class 0.000 title 1
- 206010006482 Bronchospasm Diseases 0.000 abstract 1
- 208000027771 Obstructive airways disease Diseases 0.000 abstract 1
- 239000000048 adrenergic agonist Substances 0.000 abstract 1
- 230000007885 bronchoconstriction Effects 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002441 reversible effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96643807P | 2007-08-28 | 2007-08-28 | |
| PCT/US2008/074653 WO2009032764A1 (en) | 2007-08-28 | 2008-08-28 | Acetamide stereoisomer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010001978A true MX2010001978A (es) | 2010-05-27 |
Family
ID=40291128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010001978A MX2010001978A (es) | 2007-08-28 | 2008-08-28 | Estereoisomero de acetamida. |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8501994B2 (enExample) |
| EP (1) | EP2195285B1 (enExample) |
| JP (1) | JP5468543B2 (enExample) |
| KR (1) | KR101398775B1 (enExample) |
| AR (1) | AR072943A1 (enExample) |
| AU (1) | AU2008296458B2 (enExample) |
| CA (1) | CA2696943C (enExample) |
| ES (1) | ES2684125T3 (enExample) |
| MX (1) | MX2010001978A (enExample) |
| NZ (1) | NZ583462A (enExample) |
| TW (1) | TWI505826B (enExample) |
| WO (1) | WO2009032764A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200510277A (en) * | 2003-05-27 | 2005-03-16 | Theravance Inc | Crystalline form of β2-adrenergic receptor agonist |
| US8501994B2 (en) | 2007-08-28 | 2013-08-06 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
| EP2578570A1 (en) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis. |
| EP2641900A1 (en) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor. |
| JP2022521600A (ja) * | 2019-02-22 | 2022-04-11 | シラ セラピューティック インコーポレイティッド | 吸入可能な治療剤 |
| CN111944855B (zh) * | 2020-09-03 | 2022-08-30 | 扬州中宝药业股份有限公司 | 一种合成(r)-1-(4-(苄氧基)-3-硝基苯基)-2-溴乙醇的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1415256A (en) | 1972-02-05 | 1975-11-26 | Yamanouchi Pharma Co Ltd | Alpha-aminomethylbenzyl alcohol derivatives |
| US3994974A (en) * | 1972-02-05 | 1976-11-30 | Yamanouchi Pharmaceutical Co., Ltd. | α-Aminomethylbenzyl alcohol derivatives |
| DE2366625C2 (enExample) | 1972-02-05 | 1988-06-09 | Yamanouchi Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp | |
| JPS4880523A (enExample) * | 1972-02-05 | 1973-10-29 | ||
| JPS599542B2 (ja) * | 1980-06-11 | 1984-03-03 | 山之内製薬株式会社 | 新規な３−アシルアミノ−４−ヒドロキシ−α−（アラルキルアミノメチル）ベンジルアルコ−ルの製法 |
| ES2005492A6 (es) | 1987-12-23 | 1989-03-01 | Lasa Lab | Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i). |
| ES2031407A6 (es) | 1988-10-05 | 1992-12-01 | Lasa Lab | Mejoras introducidas en el objeto de la patente principal n{ 8703715 por: procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2-((2-(4-metoxifenil)-1-metiletil)amino)etil)fenil)formamida". |
| CN1083831C (zh) | 1996-01-10 | 2002-05-01 | 旭化成株式会社 | 新的三环化合物及含有它们的药物组合物 |
| DK0938467T3 (da) | 1996-11-11 | 2002-10-07 | Sepracor Inc | Fremgangsmåde til fremstilling af optisk rene isomerer af formoterol |
| US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
| US6303145B2 (en) * | 1999-05-10 | 2001-10-16 | Sepracor Inc. | (S,R) formoterol methods and compositions |
| US6472563B1 (en) * | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
| US7718822B2 (en) * | 2007-08-28 | 2010-05-18 | Sepracor Inc. | Carbamate Stereoisomer |
| US8501994B2 (en) * | 2007-08-28 | 2013-08-06 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
-
2008
- 2008-08-22 US US12/196,520 patent/US8501994B2/en not_active Expired - Fee Related
- 2008-08-26 TW TW097132495A patent/TWI505826B/zh not_active IP Right Cessation
- 2008-08-27 AR ARP080103726A patent/AR072943A1/es unknown
- 2008-08-28 CA CA2696943A patent/CA2696943C/en active Active
- 2008-08-28 EP EP08829102.6A patent/EP2195285B1/en not_active Not-in-force
- 2008-08-28 NZ NZ583462A patent/NZ583462A/en not_active IP Right Cessation
- 2008-08-28 ES ES08829102.6T patent/ES2684125T3/es active Active
- 2008-08-28 AU AU2008296458A patent/AU2008296458B2/en not_active Ceased
- 2008-08-28 JP JP2010523136A patent/JP5468543B2/ja not_active Expired - Fee Related
- 2008-08-28 KR KR1020107006647A patent/KR101398775B1/ko not_active Expired - Fee Related
- 2008-08-28 WO PCT/US2008/074653 patent/WO2009032764A1/en not_active Ceased
- 2008-08-28 MX MX2010001978A patent/MX2010001978A/es active IP Right Grant
-
2013
- 2013-07-03 US US13/934,996 patent/US8664441B2/en active Active
-
2014
- 2014-01-17 US US14/157,793 patent/US9040588B2/en active Active
-
2015
- 2015-04-22 US US14/692,843 patent/US9499476B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2696943C (en) | 2015-05-26 |
| US9040588B2 (en) | 2015-05-26 |
| AR072943A1 (es) | 2010-10-06 |
| CA2696943A1 (en) | 2009-03-12 |
| US20140135300A1 (en) | 2014-05-15 |
| AU2008296458A1 (en) | 2009-03-12 |
| US8501994B2 (en) | 2013-08-06 |
| US9499476B2 (en) | 2016-11-22 |
| WO2009032764A1 (en) | 2009-03-12 |
| TWI505826B (zh) | 2015-11-01 |
| EP2195285A1 (en) | 2010-06-16 |
| KR101398775B1 (ko) | 2014-05-27 |
| US20130296607A1 (en) | 2013-11-07 |
| KR20100047333A (ko) | 2010-05-07 |
| TW200913984A (en) | 2009-04-01 |
| NZ583462A (en) | 2012-03-30 |
| JP5468543B2 (ja) | 2014-04-09 |
| JP2010538010A (ja) | 2010-12-09 |
| EP2195285B1 (en) | 2018-08-01 |
| US20150225334A1 (en) | 2015-08-13 |
| US8664441B2 (en) | 2014-03-04 |
| ES2684125T3 (es) | 2018-10-01 |
| AU2008296458B2 (en) | 2014-01-16 |
| US20090060922A1 (en) | 2009-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |