MX2009010411A - Minicelulas intactas, obtenidas de bacterias, que abarcan acido nucleico funcional libre de plasmido para suministro in vivo a celulas de mamifero. - Google Patents

Minicelulas intactas, obtenidas de bacterias, que abarcan acido nucleico funcional libre de plasmido para suministro in vivo a celulas de mamifero.

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Publication number
MX2009010411A
MX2009010411A MX2009010411A MX2009010411A MX2009010411A MX 2009010411 A MX2009010411 A MX 2009010411A MX 2009010411 A MX2009010411 A MX 2009010411A MX 2009010411 A MX2009010411 A MX 2009010411A MX 2009010411 A MX2009010411 A MX 2009010411A
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Mexico
Prior art keywords
nucleic acid
functional nucleic
bacterially
mammalian cells
derived
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MX2009010411A
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English (en)
Inventor
Jennifer Macdiarmid
Himanshu Brahmbhatt
Toby Hulf
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Engeneic Molecular Delivery Pty Ltd
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Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Publication of MX2009010411A publication Critical patent/MX2009010411A/es

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Abstract

Minicélulas intactas, obtenidas a partir de bacterias, pueden introducir de manera segura cantidades terapéuticamente efectivas de ácido nucleico funcional libre de plásmido a células objetivo de mamífero. Para este fin, el ácido nucleico funcional se puede empacar directamente dentro de las minicélulas intactas, sin recurrir a construcciones de expresión, a la maquinaria de expresión de la célula hospedera, a compuestos químicos agresivos o a electroporación.
MX2009010411A 2007-03-30 2008-03-26 Minicelulas intactas, obtenidas de bacterias, que abarcan acido nucleico funcional libre de plasmido para suministro in vivo a celulas de mamifero. MX2009010411A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90907407P 2007-03-30 2007-03-30
PCT/IB2008/002984 WO2009027830A2 (en) 2007-03-30 2008-03-26 Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

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Publication Number Publication Date
MX2009010411A true MX2009010411A (es) 2009-11-23

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MX2009010411A MX2009010411A (es) 2007-03-30 2008-03-26 Minicelulas intactas, obtenidas de bacterias, que abarcan acido nucleico funcional libre de plasmido para suministro in vivo a celulas de mamifero.

Country Status (18)

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EP (5) EP3564372A1 (es)
JP (1) JP5167338B2 (es)
CN (2) CN101715489B (es)
AU (1) AU2008291833B2 (es)
CA (3) CA2844647C (es)
CY (1) CY1119031T1 (es)
DK (2) DK2145002T3 (es)
ES (2) ES2534435T3 (es)
HK (2) HK1138326A1 (es)
HR (2) HRP20150328T1 (es)
LT (1) LT2865755T (es)
MX (1) MX2009010411A (es)
NZ (1) NZ580487A (es)
PL (2) PL2145002T3 (es)
PT (2) PT2145002E (es)
SG (2) SG10201804257RA (es)
SI (2) SI2865755T1 (es)
WO (1) WO2009027830A2 (es)

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EP2532746A3 (en) 2013-08-14
HRP20150328T1 (hr) 2015-05-22
CY1119031T1 (el) 2018-01-10
WO2009027830A3 (en) 2009-05-14
CA2682704A1 (en) 2009-03-05
SI2145002T1 (sl) 2015-05-29
DK2145002T3 (en) 2015-04-20
EP2865755A3 (en) 2015-05-06
EP2145002B1 (en) 2015-01-07
CA2844647A1 (en) 2009-03-05
CA2933978C (en) 2018-08-21
HK1209786A1 (en) 2016-04-08
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EP2532746A2 (en) 2012-12-12
AU2008291833B2 (en) 2012-11-08
PL2865755T3 (pl) 2017-08-31
WO2009027830A2 (en) 2009-03-05
EP2865755B1 (en) 2017-02-01
CN105854029A (zh) 2016-08-17
CA2844647C (en) 2016-07-26
EP2865755A2 (en) 2015-04-29
JP5167338B2 (ja) 2013-03-21
AU2008291833A1 (en) 2009-03-05
SG10201507969PA (en) 2015-10-29
CN101715489A (zh) 2010-05-26
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DK2865755T3 (en) 2017-05-15
SI2865755T1 (sl) 2017-06-30
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ES2534435T3 (es) 2015-04-22
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PT2865755T (pt) 2017-05-26
EP3564372A1 (en) 2019-11-06
EP3205724A1 (en) 2017-08-16
CA2682704C (en) 2014-07-08
PT2145002E (pt) 2015-04-29
HK1138326A1 (en) 2010-08-20
HRP20170662T1 (hr) 2017-07-14
ES2626179T3 (es) 2017-07-24
EP3205724B1 (en) 2019-05-08
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CN105854029B (zh) 2019-10-18

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