PL2865755T3 - Nienaruszone komórki pochodzenia bakteryjnego, obejmujące regulatorowy RNA - Google Patents

Nienaruszone komórki pochodzenia bakteryjnego, obejmujące regulatorowy RNA

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Publication number
PL2865755T3
PL2865755T3 PL15150129T PL15150129T PL2865755T3 PL 2865755 T3 PL2865755 T3 PL 2865755T3 PL 15150129 T PL15150129 T PL 15150129T PL 15150129 T PL15150129 T PL 15150129T PL 2865755 T3 PL2865755 T3 PL 2865755T3
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PL
Poland
Prior art keywords
regulatory rna
bacterially derived
intact minicells
encompassing
encompassing regulatory
Prior art date
Application number
PL15150129T
Other languages
English (en)
Inventor
Himanshu Brahmbatt
Jennifer Macdiarmid
Toby Hulf
Original Assignee
Engeneic Molecular Delivery Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Publication of PL2865755T3 publication Critical patent/PL2865755T3/pl

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091Purification or manufacturing processes for gene therapy compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
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    • C12Y207/11021Polo kinase (2.7.11.21)
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    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
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    • C12N2310/00Structure or type of the nucleic acid
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    • C12N2310/141MicroRNAs, miRNAs
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PL15150129T 2007-03-30 2008-03-26 Nienaruszone komórki pochodzenia bakteryjnego, obejmujące regulatorowy RNA PL2865755T3 (pl)

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Application Number Priority Date Filing Date Title
US90907407P 2007-03-30 2007-03-30

Publications (1)

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PL2865755T3 true PL2865755T3 (pl) 2017-08-31

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PL08828079T PL2145002T3 (pl) 2007-03-30 2008-03-26 Nienaruszone minikomórki pochodzenia bakteryjnego, które obejmują funkcjonalny kwas nukleinowy pozbawiony plazmidu do dostarczania in vivo do komórek ssaczych
PL15150129T PL2865755T3 (pl) 2007-03-30 2008-03-26 Nienaruszone komórki pochodzenia bakteryjnego, obejmujące regulatorowy RNA

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PL08828079T PL2145002T3 (pl) 2007-03-30 2008-03-26 Nienaruszone minikomórki pochodzenia bakteryjnego, które obejmują funkcjonalny kwas nukleinowy pozbawiony plazmidu do dostarczania in vivo do komórek ssaczych

Country Status (17)

Country Link
EP (5) EP3205724B1 (pl)
JP (1) JP5167338B2 (pl)
CN (2) CN105854029B (pl)
AU (1) AU2008291833B2 (pl)
CA (3) CA2844647C (pl)
CY (1) CY1119031T1 (pl)
DK (2) DK2865755T3 (pl)
ES (2) ES2534435T3 (pl)
HR (2) HRP20150328T1 (pl)
LT (1) LT2865755T (pl)
MX (1) MX2009010411A (pl)
NZ (1) NZ580487A (pl)
PL (2) PL2145002T3 (pl)
PT (2) PT2145002E (pl)
SG (2) SG10201507969PA (pl)
SI (2) SI2145002T1 (pl)
WO (1) WO2009027830A2 (pl)

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DK2865755T3 (en) 2017-05-15
CY1119031T1 (el) 2018-01-10
NZ580487A (en) 2012-04-27
EP2865755B1 (en) 2017-02-01
HK1138326A1 (en) 2010-08-20
CA2933978C (en) 2018-08-21
EP3205724A1 (en) 2017-08-16
CN105854029A (zh) 2016-08-17
CA2844647C (en) 2016-07-26
CA2933978A1 (en) 2009-03-05
CA2844647A1 (en) 2009-03-05
MX2009010411A (es) 2009-11-23
AU2008291833B2 (en) 2012-11-08
EP2145002B1 (en) 2015-01-07
SG10201804257RA (en) 2018-06-28
EP3564372A1 (en) 2019-11-06
CN101715489A (zh) 2010-05-26
WO2009027830A3 (en) 2009-05-14
JP5167338B2 (ja) 2013-03-21
SI2865755T1 (sl) 2017-06-30
ES2534435T3 (es) 2015-04-22
HRP20170662T1 (hr) 2017-07-14
HRP20150328T1 (hr) 2015-05-22
CN105854029B (zh) 2019-10-18
PT2145002E (pt) 2015-04-29
EP3205724B1 (en) 2019-05-08
LT2865755T (lt) 2017-07-25
EP2865755A3 (en) 2015-05-06
EP2532746A3 (en) 2013-08-14
ES2626179T3 (es) 2017-07-24
HK1209786A1 (en) 2016-04-08
CN101715489B (zh) 2016-05-25
WO2009027830A2 (en) 2009-03-05
JP2010523487A (ja) 2010-07-15
CA2682704C (en) 2014-07-08
PL2145002T3 (pl) 2015-06-30
SG10201507969PA (en) 2015-10-29
EP2145002A2 (en) 2010-01-20
SI2145002T1 (sl) 2015-05-29
EP2865755A2 (en) 2015-04-29
PT2865755T (pt) 2017-05-26
EP2532746A2 (en) 2012-12-12
AU2008291833A1 (en) 2009-03-05
DK2145002T3 (en) 2015-04-20
CA2682704A1 (en) 2009-03-05

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