MX2009009659A - Mesilato de imatinib. - Google Patents

Mesilato de imatinib.

Info

Publication number
MX2009009659A
MX2009009659A MX2009009659A MX2009009659A MX2009009659A MX 2009009659 A MX2009009659 A MX 2009009659A MX 2009009659 A MX2009009659 A MX 2009009659A MX 2009009659 A MX2009009659 A MX 2009009659A MX 2009009659 A MX2009009659 A MX 2009009659A
Authority
MX
Mexico
Prior art keywords
imatinib mesylate
imatinib
making
solid dispersion
carrier
Prior art date
Application number
MX2009009659A
Other languages
English (en)
Inventor
Surya Narayana Devarakonda
Minakshi Asnani
Munaswamy Sekhar Nariyam
Arjun Kumar Tummala
Vamsi Krishna Mudapaka
Srinivas Benda
Subba Reddy Peddireddy
Balaji Raghupati
Raghavendracharyulu Venkata Palle
Subrahmanyam Raghupati Rama Vinjamuri
Vijay Bhailalbhai Patel
Original Assignee
Reddys Lab Ltd Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Ltd Dr filed Critical Reddys Lab Ltd Dr
Publication of MX2009009659A publication Critical patent/MX2009009659A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se proporciona una dispersión sólida de mesilato de imatinib que incluye mesilato de imatinib y un portador farmacéuticamente aceptable, en donde el portador es un derivado de celulosa. También se proporciona un proceso para elaborar una dispersión sólida y un proceso para elaborar imatinib.
MX2009009659A 2007-03-12 2008-03-12 Mesilato de imatinib. MX2009009659A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN497CH2007 2007-03-12
IN2149CH2007 2007-09-24
US97917207P 2007-10-11 2007-10-11
PCT/US2008/056588 WO2008112722A2 (en) 2007-03-12 2008-03-12 Imatinib mesylate

Publications (1)

Publication Number Publication Date
MX2009009659A true MX2009009659A (es) 2009-09-22

Family

ID=39705055

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009659A MX2009009659A (es) 2007-03-12 2008-03-12 Mesilato de imatinib.

Country Status (10)

Country Link
US (1) US20100087444A1 (es)
EP (1) EP2120877A2 (es)
JP (1) JP2010521477A (es)
KR (1) KR20090128396A (es)
CN (1) CN101677955A (es)
BR (1) BRPI0808840A2 (es)
CA (1) CA2680249A1 (es)
IL (1) IL200848A0 (es)
MX (1) MX2009009659A (es)
WO (1) WO2008112722A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7550591B2 (en) * 2007-05-02 2009-06-23 Chemagis Ltd. Imatinib production process
PT2305263E (pt) * 2007-06-07 2012-10-22 Novartis Ag Formas amorfas estabilizadas de mesilato de imatinib
WO2009080366A1 (en) * 2007-12-22 2009-07-02 Synthon B.V. A process of making imatinib
CZ20098A3 (cs) * 2009-01-13 2010-07-21 Zentiva, K.S. Lékové formy inhibitoru tyrosinových kináz
SI2582689T1 (sl) 2010-06-18 2017-05-31 Krka, D.D., Novo Mesto Nova polimorfna oblika imatinib baze in priprava njenih soli
WO2012004801A1 (en) * 2010-07-07 2012-01-12 Hetero Research Foundation Process for imatinib mesylate
CN101921260B (zh) * 2010-09-16 2013-01-16 山东金城医药化工股份有限公司 一种伊马替尼的制备方法
CN101985442B (zh) * 2010-09-19 2013-04-03 南京卡文迪许生物工程技术有限公司 一种便捷的制备高纯度的伊马替尼及其甲磺酸盐的方法
KR101139431B1 (ko) 2011-05-30 2012-04-27 (주)비씨월드제약 이매티닙 염기의 신규한 제조방법
CA2856692C (en) 2011-11-24 2016-06-28 Imuneks Farma Ilac Sanayi Ve Ticaret A.S. Imatinib solid dosage forms reconstituted just before use
WO2013150544A2 (en) * 2012-04-02 2013-10-10 Hetero Research Foundation Ivabradine hydrochloride solid dispersion
EP2749269A1 (en) * 2012-12-31 2014-07-02 Deva Holding Anonim Sirketi Process for the preparation of adsorbates of imatinib
CN104888228A (zh) * 2015-05-29 2015-09-09 连云港杰瑞药业有限公司 一种甲苯磺酸索拉非尼固体分散体及其制备方法
EP3658190A1 (en) 2017-07-26 2020-06-03 FTF Pharma Private Limited Liquid dosage forms of imatinib
AU2020282470A1 (en) * 2019-05-31 2022-01-27 Jiangsu Hengrui Medicine Co., Ltd. Solid dispersion and preparation method therefor
US20220265653A1 (en) 2019-07-15 2022-08-25 Intas Pharmaceuticals Ltd. Pharmaceutical composition of imatinib
CN110693839B (zh) * 2019-11-19 2022-03-08 乐普药业股份有限公司 一种甲磺酸仑伐替尼固体分散体及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW225528B (es) * 1992-04-03 1994-06-21 Ciba Geigy Ag
US5521184A (en) * 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
WO2004106326A1 (en) * 2003-06-02 2004-12-09 Hetero Drugs Limited Novel polymorphs of imatinib mesylate
WO2006040779A2 (en) * 2004-10-11 2006-04-20 Natco Pharma Limited Controlled release gastric floating matrix formulation containing imatinib
MY148074A (en) * 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
ES2341996T3 (es) * 2005-06-03 2010-06-30 Elan Pharma International Limited Formulaciones de mesilato de imatinib en forma de manoparticulas.
US20060223816A1 (en) * 2006-05-08 2006-10-05 Chemagis Ltd. Imatinib mesylate alpha form and production process therefor
BRPI0715634A2 (pt) * 2006-09-01 2013-07-02 Teva Pharma composiÇÕes de imatinibe

Also Published As

Publication number Publication date
JP2010521477A (ja) 2010-06-24
WO2008112722A3 (en) 2008-11-06
KR20090128396A (ko) 2009-12-15
CN101677955A (zh) 2010-03-24
WO2008112722A2 (en) 2008-09-18
EP2120877A2 (en) 2009-11-25
CA2680249A1 (en) 2008-09-18
US20100087444A1 (en) 2010-04-08
IL200848A0 (en) 2010-05-17
BRPI0808840A2 (pt) 2014-09-02

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Legal Events

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