MX2009008170A - Nuevos biomateriales para la distribucion de farmaco ocular y metodo para hacerlos y utilizarlos. - Google Patents
Nuevos biomateriales para la distribucion de farmaco ocular y metodo para hacerlos y utilizarlos.Info
- Publication number
- MX2009008170A MX2009008170A MX2009008170A MX2009008170A MX2009008170A MX 2009008170 A MX2009008170 A MX 2009008170A MX 2009008170 A MX2009008170 A MX 2009008170A MX 2009008170 A MX2009008170 A MX 2009008170A MX 2009008170 A MX2009008170 A MX 2009008170A
- Authority
- MX
- Mexico
- Prior art keywords
- drug delivery
- making
- same
- ocular drug
- novel biomaterials
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Birds (AREA)
Abstract
Se describe un nuevo biomaterial que propiedades únicas que lo hacen útil en las aplicaciones de distribución de fármaco ocular en donde los fármacos se seleccionan del grupo que consiste de una prostaglandina, una prostamida, un fármaco antiinflamatorio no esteroide (NSAID) , y un corticoesteroide, y sus mezclas, derivados, sales y ésteres.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88755907P | 2007-01-31 | 2007-01-31 | |
PCT/US2008/001301 WO2008094659A2 (en) | 2007-01-31 | 2008-01-31 | Novel biomaterials for ocular drug delivery and a method for making and using same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009008170A true MX2009008170A (es) | 2009-08-12 |
Family
ID=39409833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009008170A MX2009008170A (es) | 2007-01-31 | 2008-01-31 | Nuevos biomateriales para la distribucion de farmaco ocular y metodo para hacerlos y utilizarlos. |
Country Status (9)
Country | Link |
---|---|
US (5) | US9855337B2 (es) |
EP (2) | EP2425816A3 (es) |
JP (2) | JP5541926B2 (es) |
KR (1) | KR20090108723A (es) |
AU (1) | AU2008211083B2 (es) |
BR (1) | BRPI0807065A2 (es) |
CA (1) | CA2676919C (es) |
MX (1) | MX2009008170A (es) |
WO (2) | WO2008094659A2 (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2848648C (en) | 2006-06-02 | 2017-10-10 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
US20080248508A1 (en) * | 2006-08-17 | 2008-10-09 | Shenda Baker | Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials |
EP2425816A3 (en) * | 2007-01-31 | 2014-04-30 | Allergan, Inc. | A pharmaceutical composition for use in treating an ocular disease or condition and a method for producing the composition |
NZ599605A (en) | 2007-02-19 | 2013-11-29 | Marinepolymer Tech Inc | Hemostatic compositions and therapeutic regimens |
US20100009009A1 (en) * | 2008-07-10 | 2010-01-14 | Micropure, Inc. | Method and composition for prevention and treatment of oral fungal infections |
CN101780105B (zh) * | 2009-01-20 | 2011-09-28 | 沈阳兴齐制药有限公司 | 小牛血去蛋白提取物的滴眼液 |
US20100233101A1 (en) | 2009-02-13 | 2010-09-16 | Micropure, Inc. | Composition and method for the oxidative consumption of salivary biomolecules |
US9271925B2 (en) | 2013-03-11 | 2016-03-01 | Bioinspire Technologies, Inc. | Multi-layer biodegradable device having adjustable drug release profile |
WO2011035020A1 (en) * | 2009-09-18 | 2011-03-24 | Bioinspire Technologies, Inc. | Free-standing biodegradable patch |
CN101695583B (zh) * | 2009-10-29 | 2012-12-26 | 中国人民解放军第三军医大学第一附属医院 | 一种用于组织修复的颗粒状生物材料及其制备方法 |
NZ602909A (en) | 2010-04-15 | 2015-01-30 | Marinepolymer Tech Inc | Anti-bacterial applications of poly -n-acetylglucosamine nanofibers |
EP2635261B1 (en) * | 2010-11-06 | 2019-10-23 | Marine Polymer Technologies, Inc. | Compositions and methods for nanopolymer-based nucleic acid delivery |
BR112013020719B1 (pt) * | 2011-02-14 | 2018-04-17 | Allergan, Inc. | Composições de derivados de bimatoprost tipo éster e métodos |
CA2832859C (en) | 2011-04-15 | 2020-06-16 | Marine Polymer Technologies, Inc. | Treatment of disease with poly-n-acetylglucosamine nanofibers |
US9962401B2 (en) * | 2011-09-27 | 2018-05-08 | Purdue Research Foundation | Chitosan derivatives for inactivation of endotoxins and surface protection of nanoparticles |
CA2849192C (en) * | 2011-10-12 | 2019-09-24 | Ascendis Pharma Ophthalmology Division A/S | Prevention and treatment of ocular conditions |
US8968790B2 (en) * | 2011-12-09 | 2015-03-03 | Shaker A. Mousa | Nanoformulation of vitamin D derivatives and/or vitamin D metabolites |
US9956291B2 (en) * | 2012-07-10 | 2018-05-01 | Shaker A. Mousa | Nanoformulation and methods of use of thyroid receptor beta1 agonists for liver targeting |
CN104884093A (zh) * | 2012-12-07 | 2015-09-02 | 阿森迪斯药物股份有限公司 | 载体连接型前列腺素类前药 |
TWI485189B (zh) | 2012-12-28 | 2015-05-21 | Ind Tech Res Inst | 固體製劑及其製造方法 |
EP3569262A1 (en) | 2013-03-14 | 2019-11-20 | Tricol Biomedical, Inc. | Biocompatible and bioabsorbable derivatized chitosan compositions |
GB201309788D0 (en) * | 2013-05-31 | 2013-07-17 | Medtrade Products Ltd | Process for the removal of contamination from a raw material |
LT3139903T (lt) | 2014-05-07 | 2019-09-10 | Croma-Pharma Gesellschaft M.B.H. | Vandeninis akių tirpalas ir sausų akių sindromo gydymo būdas |
US10449272B2 (en) | 2015-10-16 | 2019-10-22 | Industrial Technology Research Institute | Hydrogel composition and method for using the same |
US10813943B2 (en) | 2015-10-30 | 2020-10-27 | Croma-Pharma Gesellschaft M.B.H. | Therapeutic use of a sterile aqueous ophthalmic solution |
RU2741912C2 (ru) | 2015-10-30 | 2021-01-29 | Крома-Фарма Гезелльшафт М.Б.Х. | Применение в терапии стерильного водного офтальмологического раствора |
WO2017116908A1 (en) * | 2015-12-28 | 2017-07-06 | Alumend, Llc | Compositions and methods to affect skin irritation |
KR102472774B1 (ko) | 2016-08-19 | 2022-11-30 | 오라시스 파마슈티칼스 엘티디. | 안과용 약학 조성물 및 이와 관련된 용도 |
CA3020197C (en) | 2017-09-01 | 2024-06-04 | Micropure, Inc. | Aliphatic anionic compounds and oxidative compounds with improved stability and efficacy for use in pharmaceutical compositions |
CN110343263A (zh) * | 2018-04-02 | 2019-10-18 | 中国海洋大学 | 一种基于氢氧化钾和低温溶解壳聚糖的方法 |
WO2020146353A1 (en) | 2019-01-08 | 2020-07-16 | Alumend, Llc | Topical compositions containing low molecular weight chitosan derivatives |
KR102119693B1 (ko) * | 2019-10-31 | 2020-06-05 | 경희대학교 산학협력단 | 숙신화 콜라겐-피브리노겐 하이드로겔의 제조방법 |
EP4125749A4 (en) * | 2020-04-03 | 2024-05-08 | Biotissue Holdings Inc | METHOD OF USING UMBILICAL CORD PRODUCTS FOR THE TREATMENT OF OCULAR SURFACE DISEASES |
CN113440643B (zh) * | 2021-06-10 | 2022-04-29 | 武汉大学 | 一种可吸收外科材料的表面抗菌处理方法 |
CN113881070B (zh) * | 2021-11-09 | 2022-11-15 | 中北大学 | 具有光-应力双重响应的碳量子点/壳聚糖衍生物水凝胶的制备方法及应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474767A (en) * | 1990-07-26 | 1995-12-12 | Monsanto Company | Polyamines and method for preparation thereof |
FR2707878A1 (fr) | 1993-07-21 | 1995-01-27 | Imedex | Nouvelles compositions adhésives à usage chirurgical. |
US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
US5510102A (en) | 1995-01-23 | 1996-04-23 | The Regents Of The University Of California | Plasma and polymer containing surgical hemostatic adhesives |
TW389694B (en) * | 1995-08-17 | 2000-05-11 | Novartis Ag | Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics |
US6015474A (en) | 1997-06-20 | 2000-01-18 | Protein Polymer Technologies | Methods of using primer molecules for enhancing the mechanical performance of tissue adhesives and sealants |
US6200595B1 (en) | 1998-04-24 | 2001-03-13 | Kuraray Co., Ltd. | Medical adhesive |
JP2000288079A (ja) | 1999-04-07 | 2000-10-17 | Toyobo Co Ltd | 生体組織用接着剤 |
US6602952B1 (en) * | 1999-06-11 | 2003-08-05 | Shearwater Corporation | Hydrogels derived from chitosan and poly(ethylene glycol) or related polymers |
US6310188B1 (en) | 2000-01-24 | 2001-10-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for producing chitin or chitosan |
US6991652B2 (en) | 2000-06-13 | 2006-01-31 | Burg Karen J L | Tissue engineering composite |
US20040047892A1 (en) * | 2000-11-15 | 2004-03-11 | Desrosiers Eric Andre | Filler composition for soft tissue augmentation and reconstructive surgery |
US6756363B1 (en) * | 2000-11-17 | 2004-06-29 | Wound Healing Of Oklahoma, Inc. | Solutions and films of glycated chitosan |
KR100507968B1 (ko) * | 2001-08-18 | 2005-08-17 | 한국과학기술연구원 | 자기집합체를 형성하는 항암제-키토산 복합체 및 그의제조방법 |
ATA13842001A (de) * | 2001-08-31 | 2002-10-15 | Mucobiomer Biotechnologische F | Chitosan-thio-alkyl-amidin konjugate und deren kosmetische sowie pharmazeutische verwendung |
ES2371501T3 (es) | 2003-11-05 | 2012-01-03 | Photobiomed Corporation | Tejidos de unión y proteínas de reticulación con compuestos de naftalimida. |
WO2005113608A1 (en) | 2004-05-20 | 2005-12-01 | Mentor Corporation | Method of covalently linking hyaluronan and chitosan |
US20050283004A1 (en) * | 2004-06-18 | 2005-12-22 | Hopax Chemicals Manufacturing Co., Ltd. | Alkylsulfonated polyaminosaccharides |
KR100578382B1 (ko) * | 2004-07-16 | 2006-05-11 | 나재운 | 항암제의 전달체용 수용성 키토산 나노입자 및 그 제조방법 |
AU2005304034B2 (en) * | 2004-11-09 | 2012-02-16 | Santen Sas | Ophthalmic emulsions containing an immunosuppressive agent |
GB0615834D0 (en) * | 2006-08-09 | 2006-09-20 | Univ Glasgow | Polymeric micellar clusters and their uses in formulating drugs |
EP2425816A3 (en) * | 2007-01-31 | 2014-04-30 | Allergan, Inc. | A pharmaceutical composition for use in treating an ocular disease or condition and a method for producing the composition |
-
2008
- 2008-01-31 EP EP11191300.0A patent/EP2425816A3/en not_active Withdrawn
- 2008-01-31 CA CA2676919A patent/CA2676919C/en not_active Expired - Fee Related
- 2008-01-31 MX MX2009008170A patent/MX2009008170A/es active IP Right Grant
- 2008-01-31 BR BRPI0807065A patent/BRPI0807065A2/pt not_active IP Right Cessation
- 2008-01-31 US US12/023,963 patent/US9855337B2/en active Active
- 2008-01-31 WO PCT/US2008/001301 patent/WO2008094659A2/en active Application Filing
- 2008-01-31 EP EP08725018A patent/EP2114370B1/en not_active Not-in-force
- 2008-01-31 AU AU2008211083A patent/AU2008211083B2/en not_active Ceased
- 2008-01-31 WO PCT/US2008/001332 patent/WO2008094675A2/en active Application Filing
- 2008-01-31 KR KR1020097018022A patent/KR20090108723A/ko not_active Application Discontinuation
- 2008-01-31 JP JP2009548305A patent/JP5541926B2/ja not_active Expired - Fee Related
- 2008-01-31 US US12/023,977 patent/US8252771B2/en not_active Expired - Fee Related
-
2014
- 2014-03-06 JP JP2014044210A patent/JP2014129408A/ja active Pending
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2015
- 2015-12-22 US US14/978,512 patent/US9884121B2/en active Active
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2017
- 2017-12-29 US US15/858,315 patent/US20180344858A1/en not_active Abandoned
-
2018
- 2018-02-05 US US15/888,586 patent/US20180344859A1/en not_active Abandoned
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AU2008211083B2 (en) | 2013-08-01 |
CA2676919C (en) | 2013-01-29 |
EP2425816A3 (en) | 2014-04-30 |
WO2008094675A2 (en) | 2008-08-07 |
EP2114370B1 (en) | 2012-10-03 |
WO2008094659A2 (en) | 2008-08-07 |
WO2008094675A3 (en) | 2009-11-26 |
US20180344859A1 (en) | 2018-12-06 |
EP2425816A2 (en) | 2012-03-07 |
US8252771B2 (en) | 2012-08-28 |
CA2676919A1 (en) | 2008-08-07 |
US20180344858A1 (en) | 2018-12-06 |
JP2010516814A (ja) | 2010-05-20 |
JP5541926B2 (ja) | 2014-07-09 |
JP2014129408A (ja) | 2014-07-10 |
WO2008094659A3 (en) | 2009-05-14 |
EP2114370A2 (en) | 2009-11-11 |
AU2008211083A1 (en) | 2008-08-07 |
US9855337B2 (en) | 2018-01-02 |
US20160175449A1 (en) | 2016-06-23 |
US20080207561A1 (en) | 2008-08-28 |
US20080200948A1 (en) | 2008-08-21 |
BRPI0807065A2 (pt) | 2017-03-21 |
KR20090108723A (ko) | 2009-10-16 |
US9884121B2 (en) | 2018-02-06 |
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