MX2009006528A - Sal de succinato de la 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol- 3-il)fenoxi)metil)quinolina. - Google Patents
Sal de succinato de la 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol- 3-il)fenoxi)metil)quinolina.Info
- Publication number
- MX2009006528A MX2009006528A MX2009006528A MX2009006528A MX2009006528A MX 2009006528 A MX2009006528 A MX 2009006528A MX 2009006528 A MX2009006528 A MX 2009006528A MX 2009006528 A MX2009006528 A MX 2009006528A MX 2009006528 A MX2009006528 A MX 2009006528A
- Authority
- MX
- Mexico
- Prior art keywords
- methyl
- succinate salt
- pyrazol
- pyridin
- quinoline
- Prior art date
Links
- 150000003890 succinate salts Chemical class 0.000 title abstract 4
- AZEXWHKOMMASPA-UHFFFAOYSA-N 2-{[4-(1-methyl-4-pyridin-4-yl-1h-pyrazol-3-yl)phenoxy]methyl}quinoline Chemical compound C=1C=C(OCC=2N=C3C=CC=CC3=CC=2)C=CC=1C1=NN(C)C=C1C1=CC=NC=C1 AZEXWHKOMMASPA-UHFFFAOYSA-N 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87126006P | 2006-12-21 | 2006-12-21 | |
| PCT/IB2007/003819 WO2008084299A1 (en) | 2006-12-21 | 2007-12-03 | Succinate salt of 2-((4-(1-methyl-4-(pyridin-4-yl)-1h-pyrazol-3-yl) phenoxy)methyl)quinoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006528A true MX2009006528A (es) | 2009-06-26 |
Family
ID=39321475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006528A MX2009006528A (es) | 2006-12-21 | 2007-12-03 | Sal de succinato de la 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol- 3-il)fenoxi)metil)quinolina. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8283471B2 (enExample) |
| EP (1) | EP2125786B1 (enExample) |
| JP (1) | JP5254602B2 (enExample) |
| KR (2) | KR20090092338A (enExample) |
| CN (1) | CN101611029B (enExample) |
| AR (1) | AR064417A1 (enExample) |
| AT (1) | ATE502028T1 (enExample) |
| AU (1) | AU2007343135B2 (enExample) |
| BR (1) | BRPI0720936A2 (enExample) |
| CA (1) | CA2673435C (enExample) |
| CY (1) | CY1111919T1 (enExample) |
| DE (1) | DE602007013294D1 (enExample) |
| DK (1) | DK2125786T3 (enExample) |
| ES (1) | ES2360014T3 (enExample) |
| IL (1) | IL199389A (enExample) |
| MX (1) | MX2009006528A (enExample) |
| NZ (1) | NZ577716A (enExample) |
| PL (1) | PL2125786T3 (enExample) |
| PT (1) | PT2125786E (enExample) |
| RU (1) | RU2430918C2 (enExample) |
| SI (1) | SI2125786T1 (enExample) |
| TW (1) | TWI359660B (enExample) |
| WO (1) | WO2008084299A1 (enExample) |
| ZA (1) | ZA200904230B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010033045A1 (en) * | 2008-09-16 | 2010-03-25 | Igor Anatolievich Pomytkin | Compositions and methods for prevention or treatment of beta amyloid deposition |
| TWI396689B (zh) | 2008-11-14 | 2013-05-21 | Amgen Inc | 作為磷酸二酯酶10抑制劑之吡衍生物 |
| US20120214842A1 (en) * | 2011-02-18 | 2012-08-23 | Exonhit Therapeutics Sa | Methods for treating diseases of the retina |
| EP2975037A4 (en) | 2013-03-15 | 2016-08-10 | Daiichi Sankyo Co Ltd | benzothiophene derivative |
| US10039764B2 (en) | 2013-07-12 | 2018-08-07 | University Of South Alabama | Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure PDE10A expression |
| KR102233916B1 (ko) * | 2019-05-28 | 2021-03-30 | 주식회사 엘지생활건강 | Pq1 숙신산을 포함하는 피부 보습, 주름 개선 및 탄력 증진용 조성물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4105551A1 (de) * | 1991-02-22 | 1992-08-27 | Bayer Ag | 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| EA011451B1 (ru) * | 2001-02-12 | 2009-04-28 | Уайт | Новая соль сукцинат о-десметилвенлафаксина |
| IL161326A0 (en) * | 2001-11-29 | 2004-09-27 | Pfizer Prod Inc | Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2 (11),3,5,7,9-pentaene and pharmaceutical compositions thereof |
| CN1608062A (zh) * | 2001-12-12 | 2005-04-20 | 辉瑞产品公司 | E-2-甲氧基-n-(3-{4-[3-甲基-4-(6-甲基-吡啶-3-基氧基) -苯氨基]-喹唑啉-6基}-烯丙基)-乙酰胺的盐,其制备和抗癌用途 |
| CA2536073A1 (en) * | 2003-08-18 | 2005-02-24 | H. Lundbeck A/S | Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine |
| WO2006072828A2 (en) * | 2005-01-07 | 2006-07-13 | Pfizer Products Inc. | Heteroaromatic quinoline compounds and their use as pde10 inhibitors |
| WO2006078825A2 (en) | 2005-01-21 | 2006-07-27 | Cabot Corporation | Processes for forming nanoparticles |
| AU2006329849A1 (en) * | 2005-12-16 | 2007-07-05 | Wyeth | Lyophilized compositions of a triazolopyrimidine compound |
-
2007
- 2007-12-03 CN CN200780051566.5A patent/CN101611029B/zh not_active Expired - Fee Related
- 2007-12-03 EP EP07858987A patent/EP2125786B1/en not_active Not-in-force
- 2007-12-03 AU AU2007343135A patent/AU2007343135B2/en not_active Ceased
- 2007-12-03 CA CA2673435A patent/CA2673435C/en not_active Expired - Fee Related
- 2007-12-03 SI SI200730561T patent/SI2125786T1/sl unknown
- 2007-12-03 PL PL07858987T patent/PL2125786T3/pl unknown
- 2007-12-03 DK DK07858987.6T patent/DK2125786T3/da active
- 2007-12-03 KR KR1020097015193A patent/KR20090092338A/ko not_active Ceased
- 2007-12-03 MX MX2009006528A patent/MX2009006528A/es active IP Right Grant
- 2007-12-03 AT AT07858987T patent/ATE502028T1/de active
- 2007-12-03 KR KR1020127009903A patent/KR20120043775A/ko not_active Ceased
- 2007-12-03 RU RU2009123347/04A patent/RU2430918C2/ru not_active IP Right Cessation
- 2007-12-03 PT PT07858987T patent/PT2125786E/pt unknown
- 2007-12-03 BR BRPI0720936-3A patent/BRPI0720936A2/pt not_active IP Right Cessation
- 2007-12-03 ES ES07858987T patent/ES2360014T3/es active Active
- 2007-12-03 NZ NZ577716A patent/NZ577716A/xx not_active IP Right Cessation
- 2007-12-03 WO PCT/IB2007/003819 patent/WO2008084299A1/en not_active Ceased
- 2007-12-03 US US12/515,612 patent/US8283471B2/en not_active Expired - Fee Related
- 2007-12-03 DE DE602007013294T patent/DE602007013294D1/de active Active
- 2007-12-18 AR ARP070105692A patent/AR064417A1/es not_active Application Discontinuation
- 2007-12-19 JP JP2007327323A patent/JP5254602B2/ja not_active Expired - Fee Related
- 2007-12-20 TW TW096148920A patent/TWI359660B/zh not_active IP Right Cessation
-
2009
- 2009-06-16 IL IL199389A patent/IL199389A/en active IP Right Review Request
- 2009-06-17 ZA ZA200904230A patent/ZA200904230B/xx unknown
-
2011
- 2011-05-17 CY CY20111100481T patent/CY1111919T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2673435C (en) | 2012-10-09 |
| KR20090092338A (ko) | 2009-08-31 |
| BRPI0720936A2 (pt) | 2014-03-11 |
| AR064417A1 (es) | 2009-04-01 |
| ATE502028T1 (de) | 2011-04-15 |
| JP5254602B2 (ja) | 2013-08-07 |
| AU2007343135A1 (en) | 2008-07-17 |
| IL199389A (en) | 2014-01-30 |
| CN101611029A (zh) | 2009-12-23 |
| HK1134670A1 (en) | 2010-05-07 |
| EP2125786B1 (en) | 2011-03-16 |
| PL2125786T3 (pl) | 2011-07-29 |
| EP2125786A1 (en) | 2009-12-02 |
| SI2125786T1 (sl) | 2011-05-31 |
| TWI359660B (en) | 2012-03-11 |
| WO2008084299A1 (en) | 2008-07-17 |
| NZ577716A (en) | 2012-10-26 |
| PT2125786E (pt) | 2011-04-21 |
| US20100063089A1 (en) | 2010-03-11 |
| CY1111919T1 (el) | 2015-11-04 |
| ES2360014T3 (es) | 2011-05-31 |
| RU2009123347A (ru) | 2011-01-27 |
| ZA200904230B (en) | 2010-04-28 |
| TW200833337A (en) | 2008-08-16 |
| AU2007343135B2 (en) | 2013-03-21 |
| JP2008208114A (ja) | 2008-09-11 |
| RU2430918C2 (ru) | 2011-10-10 |
| CA2673435A1 (en) | 2008-07-17 |
| DK2125786T3 (da) | 2011-05-09 |
| DE602007013294D1 (de) | 2011-04-28 |
| KR20120043775A (ko) | 2012-05-04 |
| CN101611029B (zh) | 2014-09-10 |
| US8283471B2 (en) | 2012-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |