MX2009005688A - Material compuesto para reparacion de tejidos. - Google Patents
Material compuesto para reparacion de tejidos.Info
- Publication number
- MX2009005688A MX2009005688A MX2009005688A MX2009005688A MX2009005688A MX 2009005688 A MX2009005688 A MX 2009005688A MX 2009005688 A MX2009005688 A MX 2009005688A MX 2009005688 A MX2009005688 A MX 2009005688A MX 2009005688 A MX2009005688 A MX 2009005688A
- Authority
- MX
- Mexico
- Prior art keywords
- biocompatible composite
- composite material
- tissue repair
- tissue
- agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
- A61F2/105—Skin implants, e.g. artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30756—Cartilage endoprostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2002/0894—Muscles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Composite Materials (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente descripción proporciona un compuesto biocompatible y un método para su uso en reparación de los defectos de los tejidos, incluyendo defectos en cartílago. El compuesto biocompatible incluye un componente polimérico fibroso y un agente polimerizable, que es capaz de dar forma al compuesto biocompatible in situ, en el sitio de un defecto del tejido. En las modalidades, el sitio en reparación en que el compuesto biocompatible se aplicará puede tratarse con un agente de preparación, lo que permite la polimerización del agente polimerizable en el tejido ubicado en el sitio en reparación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/637,516 US7935363B2 (en) | 2006-12-12 | 2006-12-12 | Composite material for tissue repair |
PCT/US2007/025283 WO2008073403A2 (en) | 2006-12-12 | 2007-12-11 | Composite material for tissue repair |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009005688A true MX2009005688A (es) | 2009-09-07 |
Family
ID=39498966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009005688A MX2009005688A (es) | 2006-12-12 | 2007-12-11 | Material compuesto para reparacion de tejidos. |
Country Status (8)
Country | Link |
---|---|
US (5) | US7935363B2 (es) |
EP (1) | EP2101793A4 (es) |
JP (2) | JP2010512223A (es) |
AU (1) | AU2007332786A1 (es) |
CA (1) | CA2671449C (es) |
MX (1) | MX2009005688A (es) |
WO (1) | WO2008073403A2 (es) |
ZA (1) | ZA200904106B (es) |
Families Citing this family (39)
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US9456860B2 (en) * | 2006-03-14 | 2016-10-04 | Kci Licensing, Inc. | Bioresorbable foaming tissue dressing |
EP2187988B1 (en) * | 2007-07-19 | 2013-08-21 | Boston Scientific Limited | Endoprosthesis having a non-fouling surface |
WO2010005917A2 (en) * | 2008-07-06 | 2010-01-14 | The Curators Of The University Of Missouri | Osteochondral implants, arthroplasty methods, devices, and systems |
US20120209396A1 (en) | 2008-07-07 | 2012-08-16 | David Myung | Orthopedic implants having gradient polymer alloys |
US9889230B2 (en) * | 2008-10-17 | 2018-02-13 | Covidien Lp | Hemostatic implant |
WO2010059280A2 (en) | 2008-11-19 | 2010-05-27 | E. I. Du Pont De Nemours And Company | Fibrous tissue sealant and method of using same |
US20100331998A1 (en) * | 2009-06-30 | 2010-12-30 | Ringeisen Timothy A | Electrokinetic device for tissue repair |
ES2358403B2 (es) * | 2009-10-26 | 2011-12-13 | Universidad De Santiago De Compostela | Sistema para la administración de sustancias biológicamente activas que comprende poli-epsilón-caprolactona, poloxamina y una o varias sustancias activas. |
US8697111B2 (en) * | 2010-05-12 | 2014-04-15 | Covidien Lp | Osteochondral implant comprising osseous phase and chondral phase |
ES2370205B2 (es) * | 2010-05-18 | 2012-07-04 | Universidad De Santiago De Compostela | Uso de poloxaminas como inductoras de la diferenciacion osteogenica de celulas mesenquimales |
EP2588036A1 (en) * | 2010-07-01 | 2013-05-08 | Ecole Polytechnique Federale De Lausanne (EPFL) EPFL-TTO | Composite hydrogels |
US8834418B2 (en) | 2010-07-22 | 2014-09-16 | Covidien Lp | Molds for in situ forming materials |
US9084602B2 (en) | 2011-01-26 | 2015-07-21 | Covidien Lp | Buttress film with hemostatic action for surgical stapling apparatus |
US10159605B2 (en) * | 2011-09-15 | 2018-12-25 | Compose Element Limited | Dressing |
EP2763707B1 (en) | 2011-10-03 | 2018-03-28 | Hyalex Orthopaedics, Inc. | Polymeric adhesive for anchoring compliant materials to another surface |
CN103930133A (zh) * | 2011-11-13 | 2014-07-16 | 桑那瑞斯公司 | 原位可交联的聚合物组合物及其方法 |
KR101269423B1 (ko) * | 2011-12-22 | 2013-05-30 | 오스템임플란트 주식회사 | 체내 분해 속도 조절이 가능한 수화젤 및 그 제조 방법 |
US20130338792A1 (en) * | 2012-06-15 | 2013-12-19 | Arthrex, Inc. | Implantation of micronized allograft tissue over a microfractured defect |
US10292381B2 (en) | 2012-07-20 | 2019-05-21 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
WO2014015274A1 (en) * | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
WO2015009992A1 (en) | 2013-07-18 | 2015-01-22 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
US20160317705A1 (en) * | 2014-01-20 | 2016-11-03 | Bioteck S.P.A. | Method of making a hydrogel, hydrogel and formulation for carriers and/or substitute of connective tissues obtained using such method |
US20160051723A1 (en) * | 2014-08-21 | 2016-02-25 | Gregory J. Pomrink | Bioresorbable tissue repair composition |
CN106794280A (zh) * | 2014-10-14 | 2017-05-31 | 安东尼奥·桑布瑟蒂 | 用于骨再生的可吸收装置 |
CN104587531B (zh) * | 2014-12-25 | 2016-05-04 | 南京臻泉医药科技有限公司 | 一种修复关节软骨损伤的凝胶支架的制备方法 |
CA2972094C (en) | 2015-01-12 | 2023-10-24 | Wake Forest University Health Sciences | Multi-layer skin substitute products and methods of making and using the same |
US11077228B2 (en) | 2015-08-10 | 2021-08-03 | Hyalex Orthopaedics, Inc. | Interpenetrating polymer networks |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
CN105833338A (zh) * | 2016-04-25 | 2016-08-10 | 天津市赛宁生物工程技术有限公司 | 可用于医用组织粘合剂的有机镁盐复合物 |
KR102402097B1 (ko) | 2016-08-04 | 2022-05-25 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | 혈뇌 장벽 모델 및 그의 제조 및 사용 방법 |
US11826757B2 (en) | 2017-08-02 | 2023-11-28 | Wake Forest University Health Sciences | Niches-on-a-chip |
EP3689333A4 (en) * | 2017-09-25 | 2021-07-14 | Kyoto Prefectural Public University Corporation | LOCAL INJECTION SOLUTION WITH TWO MEDICINAL PRODUCTS FOR SUBMUCOSAL INJECTION |
US20190240335A1 (en) | 2018-02-07 | 2019-08-08 | Promedon S.A. | Biocompatible Hydrogel Compositions |
US10869950B2 (en) | 2018-07-17 | 2020-12-22 | Hyalex Orthopaedics, Inc. | Ionic polymer compositions |
CN110922645A (zh) * | 2018-09-20 | 2020-03-27 | 广州迈普再生医学科技股份有限公司 | 一种双网络水凝胶组合物、双网络水凝胶生物支架及其制备方法和应用 |
WO2021055703A1 (en) * | 2019-09-20 | 2021-03-25 | President And Fellows Of Harvard College | Tough gel-based drug delivery compositions and methods thereof |
CN111643714B (zh) * | 2020-04-29 | 2021-10-22 | 诺一迈尔(山东)医学科技有限公司 | 一种鼻腔填充材料及其制备方法 |
CN113082294A (zh) * | 2021-03-30 | 2021-07-09 | 冠昊生物科技股份有限公司 | 一种脱细胞基质支架的制备方法及通过该方法获得的脱细胞基质支架 |
CN114479449A (zh) * | 2022-03-16 | 2022-05-13 | 山东交通学院 | 一种用于地面修复与承载加固工程用复合材料、制备方法及应用 |
Family Cites Families (27)
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US5492697A (en) * | 1990-03-05 | 1996-02-20 | Board Of Regents, Univ. Of Texas System | Biodegradable implant for fracture nonunions |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
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EP0627911B1 (en) * | 1992-02-28 | 2000-10-25 | Board Of Regents The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
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WO1995010328A1 (en) * | 1993-10-12 | 1995-04-20 | Scimed Life Systems, Inc. | Apparatus and method for tissue defect repair |
US6123727A (en) * | 1995-05-01 | 2000-09-26 | Massachusetts Institute Of Technology | Tissue engineered tendons and ligaments |
US5700289A (en) * | 1995-10-20 | 1997-12-23 | North Shore University Hospital Research Corporation | Tissue-engineered bone repair using cultured periosteal cells |
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US6224893B1 (en) * | 1997-04-11 | 2001-05-01 | Massachusetts Institute Of Technology | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering |
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US6378527B1 (en) * | 1998-04-08 | 2002-04-30 | Chondros, Inc. | Cell-culture and polymer constructs |
US6818018B1 (en) * | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
DE69937584T2 (de) * | 1998-12-28 | 2008-09-18 | Neomax Co., Ltd. | Verfahren und Apparat zum Einführen von Seltenerde-Legierungspuder |
JP4163854B2 (ja) * | 1999-01-12 | 2008-10-08 | リパット・コンサルティング・アクチェンゲゼルシャフト | 骨内移植片のための表面構造 |
US6719797B1 (en) * | 1999-08-13 | 2004-04-13 | Bret A. Ferree | Nucleus augmentation with in situ formed hydrogels |
US6652883B2 (en) * | 2000-03-13 | 2003-11-25 | Biocure, Inc. | Tissue bulking and coating compositions |
AU1185002A (en) * | 2000-10-31 | 2002-05-15 | Orquest Inc | Mineralized collagen-polysaccharide matrix for bone and cartilage repair |
US6576000B2 (en) * | 2001-03-06 | 2003-06-10 | Scimed Life Systems, Inc. | Devices and methods for tissue repair |
CA2455766C (en) * | 2001-07-31 | 2011-02-08 | Tyco Healthcare Group Lp | Bioabsorbable adhesive compounds and compositions |
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US7560432B2 (en) * | 2003-11-26 | 2009-07-14 | Histogenics Corporation | In situ method for treatment and repair of meniscal injuries |
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CA2541827C (en) * | 2004-07-30 | 2013-05-14 | Histogenics Corporation | Method for in situ repair of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs and a method for preparation thereof |
US8118508B2 (en) * | 2006-11-30 | 2012-02-21 | Closure Medical Corporation | Dispenser with a frangible container and a rotating breaking member, for dispensing a polymerizable monomer adhesive |
-
2006
- 2006-12-12 US US11/637,516 patent/US7935363B2/en active Active
-
2007
- 2007-12-11 CA CA2671449A patent/CA2671449C/en not_active Expired - Fee Related
- 2007-12-11 WO PCT/US2007/025283 patent/WO2008073403A2/en active Application Filing
- 2007-12-11 AU AU2007332786A patent/AU2007332786A1/en not_active Abandoned
- 2007-12-11 EP EP07862735A patent/EP2101793A4/en not_active Withdrawn
- 2007-12-11 MX MX2009005688A patent/MX2009005688A/es active IP Right Grant
- 2007-12-11 JP JP2009541340A patent/JP2010512223A/ja active Pending
-
2009
- 2009-06-11 ZA ZA200904106A patent/ZA200904106B/xx unknown
-
2011
- 2011-05-03 US US13/099,762 patent/US8574620B2/en active Active
-
2013
- 2013-11-05 US US14/072,099 patent/US8808730B2/en active Active
-
2014
- 2014-07-11 JP JP2014143403A patent/JP2014208299A/ja not_active Withdrawn
- 2014-08-19 US US14/462,897 patent/US9216194B2/en active Active
-
2015
- 2015-12-22 US US14/978,585 patent/US20160175479A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20140065201A1 (en) | 2014-03-06 |
EP2101793A2 (en) | 2009-09-23 |
US8808730B2 (en) | 2014-08-19 |
JP2014208299A (ja) | 2014-11-06 |
AU2007332786A1 (en) | 2008-06-19 |
US20110206634A1 (en) | 2011-08-25 |
WO2008073403A3 (en) | 2008-07-31 |
WO2008073403A2 (en) | 2008-06-19 |
US9216194B2 (en) | 2015-12-22 |
US8574620B2 (en) | 2013-11-05 |
US20160175479A1 (en) | 2016-06-23 |
EP2101793A4 (en) | 2012-11-07 |
JP2010512223A (ja) | 2010-04-22 |
US7935363B2 (en) | 2011-05-03 |
US20080139694A1 (en) | 2008-06-12 |
CA2671449C (en) | 2013-09-10 |
ZA200904106B (en) | 2010-04-28 |
US20140357716A1 (en) | 2014-12-04 |
CA2671449A1 (en) | 2008-06-19 |
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