MX2008015954A - 8-[6-amino-3-piridil]xantinas sustituidas. - Google Patents
8-[6-amino-3-piridil]xantinas sustituidas.Info
- Publication number
- MX2008015954A MX2008015954A MX2008015954A MX2008015954A MX2008015954A MX 2008015954 A MX2008015954 A MX 2008015954A MX 2008015954 A MX2008015954 A MX 2008015954A MX 2008015954 A MX2008015954 A MX 2008015954A MX 2008015954 A MX2008015954 A MX 2008015954A
- Authority
- MX
- Mexico
- Prior art keywords
- minutes
- meoh
- compound
- pyridyl
- dmso
- Prior art date
Links
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Classifications
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- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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Landscapes
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| US80556406P | 2006-06-22 | 2006-06-22 | |
| US11/811,823 US7884100B2 (en) | 2006-06-16 | 2007-06-12 | Substituted 8-[6-amino-3-pyridyl]xanthines |
| PCT/US2007/013849 WO2007149277A2 (en) | 2006-06-16 | 2007-06-13 | Substituted 8-[6-amino-3-pyridyl]xanthines |
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| MX2008015954A true MX2008015954A (es) | 2009-03-06 |
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| MX2008015954A MX2008015954A (es) | 2006-06-16 | 2007-06-13 | 8-[6-amino-3-piridil]xantinas sustituidas. |
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| EP1658291B1 (en) * | 2003-08-25 | 2013-10-02 | Dogwood Pharmaceuticals, Inc. | Substituted 8-heteroaryl xanthines |
| US7618962B2 (en) * | 2005-02-25 | 2009-11-17 | Pgx Health, Llc | Pyrazolyl substituted xanthines |
| US7598379B2 (en) | 2005-02-25 | 2009-10-06 | Pgx Health, Llc | Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines |
| WO2006091897A2 (en) * | 2005-02-25 | 2006-08-31 | Adenosine Therapeutics, Llc | Derivatives of 8-substituted xanthines |
| US7884100B2 (en) | 2006-06-16 | 2011-02-08 | Pgxhealth, Llc | Substituted 8-[6-amino-3-pyridyl]xanthines |
| US7875608B2 (en) * | 2007-12-17 | 2011-01-25 | Thompson Robert D | Substituted 8-[6-amino-3pyridyl]xanthines |
| BR112023023996A2 (pt) * | 2021-05-18 | 2024-01-30 | Adovate Llc | Xantinas de piridil contendo amida cíclica como antagonistas de a2b |
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| US6117878A (en) * | 1998-02-24 | 2000-09-12 | University Of Virginia | 8-phenyl- or 8-cycloalkyl xanthine antagonists of A2B human adenosine receptors |
| US6060481A (en) * | 1998-05-28 | 2000-05-09 | The Penn State Research Foundation | Method for improving insulin sensitivity using an adenosine receptor antagonist |
| GB9817623D0 (en) * | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
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| US7317017B2 (en) * | 2002-11-08 | 2008-01-08 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
| US6977300B2 (en) * | 2001-11-09 | 2005-12-20 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
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| US7034070B2 (en) * | 2002-09-27 | 2006-04-25 | Vincent Chuang | Arylalkyl aminofunctional silanes for epoxy laminates |
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| KR101247528B1 (ko) | 2004-09-01 | 2013-04-15 | 길리애드 사이언시즈, 인코포레이티드 | Ａ２ｂ 아데노신 수용체 길항제를 사용하는 상처 치유 방법 |
| WO2006028840A2 (en) | 2004-09-03 | 2006-03-16 | United States Postal Service | Methods and systems for providing an enterprise supply management portal |
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| US7598379B2 (en) * | 2005-02-25 | 2009-10-06 | Pgx Health, Llc | Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines |
| US7618962B2 (en) * | 2005-02-25 | 2009-11-17 | Pgx Health, Llc | Pyrazolyl substituted xanthines |
| US7601723B2 (en) * | 2005-02-25 | 2009-10-13 | Pgx Health, Llc | Pyridyl substituted xanthines |
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| JP5250848B2 (ja) * | 2006-03-17 | 2013-07-31 | ギリアード サイエンシーズ， インコーポレイテッド | Ａ２ｂアデノシン受容体拮抗物質を用いる肝疾患の予防および処置の方法 |
| AU2006344750A1 (en) * | 2006-06-15 | 2007-12-27 | Targeted Genetics Corporation | Methods for treating target joints in inflammatory arthritis using AAV vectors encoding a TNF antagonist |
| US7884100B2 (en) | 2006-06-16 | 2011-02-08 | Pgxhealth, Llc | Substituted 8-[6-amino-3-pyridyl]xanthines |
| US7767685B2 (en) * | 2006-06-29 | 2010-08-03 | King Pharmaceuticals Research And Development, Inc. | Adenosine A2B receptor antagonists |
| US7875608B2 (en) * | 2007-12-17 | 2011-01-25 | Thompson Robert D | Substituted 8-[6-amino-3pyridyl]xanthines |
| CA2718983C (en) * | 2008-03-26 | 2015-12-08 | Advinus Therapeutics Pvt. Ltd. | Heterocyclic compounds as adenosine receptor antagonist |
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| EA200900010A1 (ru) | 2009-10-30 |
| MY152178A (en) | 2014-08-15 |
| JP2010500284A (ja) | 2010-01-07 |
| US20110082139A1 (en) | 2011-04-07 |
| IL195916A0 (en) | 2009-09-01 |
| BRPI0712001A2 (pt) | 2012-01-10 |
| CA2655598A1 (en) | 2007-12-27 |
| KR101413404B1 (ko) | 2014-06-27 |
| DK2029143T3 (en) | 2015-09-21 |
| US7884100B2 (en) | 2011-02-08 |
| US20080004292A1 (en) | 2008-01-03 |
| HUE026457T2 (en) | 2016-05-30 |
| KR20090029268A (ko) | 2009-03-20 |
| JP5417558B2 (ja) | 2014-02-19 |
| PT2029143E (pt) | 2015-10-20 |
| EP2029143A2 (en) | 2009-03-04 |
| AU2007261568A1 (en) | 2007-12-27 |
| BRPI0712001B1 (pt) | 2020-04-07 |
| CA2655598C (en) | 2014-10-28 |
| EP2029143A4 (en) | 2009-07-15 |
| NZ597222A (en) | 2013-06-28 |
| BRPI0712001B8 (pt) | 2021-05-25 |
| US8258142B2 (en) | 2012-09-04 |
| IL195916A (en) | 2015-06-30 |
| ES2548437T3 (es) | 2015-10-16 |
| EP2029143B1 (en) | 2015-07-08 |
| AU2007261568B2 (en) | 2013-05-16 |
| EA016791B1 (ru) | 2012-07-30 |
| CN103145712A (zh) | 2013-06-12 |
| PL2029143T3 (pl) | 2015-12-31 |
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