MX2007013876A - Uso de inhibidor de la via del factor de tejido para tratar infecciones bacterianas severas. - Google Patents

Uso de inhibidor de la via del factor de tejido para tratar infecciones bacterianas severas.

Info

Publication number
MX2007013876A
MX2007013876A MX2007013876A MX2007013876A MX2007013876A MX 2007013876 A MX2007013876 A MX 2007013876A MX 2007013876 A MX2007013876 A MX 2007013876A MX 2007013876 A MX2007013876 A MX 2007013876A MX 2007013876 A MX2007013876 A MX 2007013876A
Authority
MX
Mexico
Prior art keywords
tfpi
severe bacterial
bacterial infections
treat severe
developing
Prior art date
Application number
MX2007013876A
Other languages
English (en)
Inventor
Stephen F Hardy
Yumin Dai
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2007013876A publication Critical patent/MX2007013876A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Metodos para tratamiento profilactico o terapeutico de un paciente en riesgo de desarrollar o a quien se ha diagnosticado que tiene una infeccion bacteriana severa, que implica la administracion de inhibidor de la via del factor de tejido (TFPI) o un analogo de TFPI a pacientes que padecen o estan en riego de desarrollar esta condicion. Los metodos implican el uso de infusion intravenosa continua de TFPI o un analogo de TFPI a dosis bajas para evitar efectos colaterales adversos.
MX2007013876A 2005-05-06 2006-05-08 Uso de inhibidor de la via del factor de tejido para tratar infecciones bacterianas severas. MX2007013876A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67846505P 2005-05-06 2005-05-06
PCT/US2006/017956 WO2006122139A2 (en) 2005-05-06 2006-05-08 Use of tfpi to treat severe bacterial infections

Publications (1)

Publication Number Publication Date
MX2007013876A true MX2007013876A (es) 2008-04-02

Family

ID=37103012

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007013876A MX2007013876A (es) 2005-05-06 2006-05-08 Uso de inhibidor de la via del factor de tejido para tratar infecciones bacterianas severas.

Country Status (16)

Country Link
US (1) US20090214506A1 (es)
EP (1) EP1877081A2 (es)
JP (1) JP2008540460A (es)
KR (1) KR20080017021A (es)
CN (1) CN101400365A (es)
AU (1) AU2006244053A1 (es)
BR (1) BRPI0611049A2 (es)
CA (1) CA2607293A1 (es)
IL (1) IL187111A0 (es)
MA (1) MA29489B1 (es)
MX (1) MX2007013876A (es)
NO (1) NO20076245L (es)
RU (1) RU2007145202A (es)
TN (1) TNSN07413A1 (es)
WO (1) WO2006122139A2 (es)
ZA (1) ZA200709520B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
WO2009129164A1 (en) * 2008-04-15 2009-10-22 Novartis Ag Pharmaceutical combinations of tfpi-fragments and an antibiotic
US8241623B1 (en) 2009-02-09 2012-08-14 David Bermudes Protease sensitivity expression system
GB0916578D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
US9597379B1 (en) 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
US8771669B1 (en) 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
US8524220B1 (en) 2010-02-09 2013-09-03 David Gordon Bermudes Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria
US9593339B1 (en) 2013-02-14 2017-03-14 David Gordon Bermudes Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
CN105473619B (zh) 2013-07-19 2020-12-15 诺和诺德股份有限公司 能够引起促凝血活性的识别组织因子途径抑制剂的n-末端部分的抗体
CN105777876B (zh) * 2016-05-26 2020-02-11 青岛农业大学 一种抗菌肽tc38及其应用
CN105777875B (zh) * 2016-05-26 2020-02-11 青岛农业大学 一种抗菌肽cstc24及其应用
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11572295B1 (en) * 2019-06-11 2023-02-07 Swamp Fox Innovations, LLC Compositions and methods for reduction of free chlorine and related odor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0500472A2 (hu) * 2001-10-15 2005-08-29 Chiron Corporation Szepszis kezelése kis dózisú szöveti faktor bioszintézis inhibitor (TFPI) beadásával
WO2005019265A1 (en) * 2003-08-13 2005-03-03 Chiron Corporation Improved method of purifying tfpi and tfpi analogs

Also Published As

Publication number Publication date
RU2007145202A (ru) 2009-06-20
BRPI0611049A2 (pt) 2010-08-10
US20090214506A1 (en) 2009-08-27
JP2008540460A (ja) 2008-11-20
AU2006244053A1 (en) 2006-11-16
NO20076245L (no) 2007-12-06
TNSN07413A1 (en) 2009-03-17
KR20080017021A (ko) 2008-02-25
WO2006122139A2 (en) 2006-11-16
CA2607293A1 (en) 2006-11-16
EP1877081A2 (en) 2008-01-16
WO2006122139A3 (en) 2007-04-26
ZA200709520B (en) 2008-11-26
MA29489B1 (fr) 2008-05-02
IL187111A0 (en) 2008-02-09
CN101400365A (zh) 2009-04-01

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