MX2007010407A - Formulacion con accion anti-tumor. - Google Patents

Formulacion con accion anti-tumor.

Info

Publication number
MX2007010407A
MX2007010407A MX2007010407A MX2007010407A MX2007010407A MX 2007010407 A MX2007010407 A MX 2007010407A MX 2007010407 A MX2007010407 A MX 2007010407A MX 2007010407 A MX2007010407 A MX 2007010407A MX 2007010407 A MX2007010407 A MX 2007010407A
Authority
MX
Mexico
Prior art keywords
oligodeoxyribonucleotides
dalton
treating tumors
tumors
produced
Prior art date
Application number
MX2007010407A
Other languages
English (en)
Spanish (es)
Inventor
Laura Iris Ferro
Massimo Iacobelli
Gunther Eissner
Original Assignee
Gentium Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT000336A external-priority patent/ITMI20050336A1/it
Application filed by Gentium Spa filed Critical Gentium Spa
Publication of MX2007010407A publication Critical patent/MX2007010407A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2007010407A 2005-03-03 2006-02-27 Formulacion con accion anti-tumor. MX2007010407A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000336A ITMI20050336A1 (it) 2005-03-03 2005-03-03 Formulazione ad attivita' anti-tumorale
US73140405P 2005-10-28 2005-10-28
PCT/EP2006/060306 WO2006094917A2 (en) 2005-03-03 2006-02-27 Oligodeoxyribonucleotides of 4000-10000 dalton for treating tumors

Publications (1)

Publication Number Publication Date
MX2007010407A true MX2007010407A (es) 2007-10-17

Family

ID=36572331

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2007010407A MX2007010407A (es) 2005-03-03 2006-02-27 Formulacion con accion anti-tumor.
MX2007010754A MX2007010754A (es) 2005-03-03 2006-02-27 Defibrotide y/u oligodeoxiribonucleotidos para tratar tumores dependientes de angiogenesis.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2007010754A MX2007010754A (es) 2005-03-03 2006-02-27 Defibrotide y/u oligodeoxiribonucleotidos para tratar tumores dependientes de angiogenesis.

Country Status (9)

Country Link
US (2) US20080194507A1 (enExample)
EP (2) EP1855697A2 (enExample)
JP (2) JP2008531647A (enExample)
KR (3) KR20070120953A (enExample)
AU (2) AU2006222045B2 (enExample)
CA (2) CA2598613A1 (enExample)
IL (3) IL185182A0 (enExample)
MX (2) MX2007010407A (enExample)
WO (2) WO2006094916A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20031714A1 (it) 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
EP1982722A1 (en) * 2007-04-16 2008-10-22 Gentium S.p.A. Use of oligotide for the treatment of renal diseases
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
US8187897B2 (en) 2008-08-19 2012-05-29 International Business Machines Corporation Fabricating product chips and die with a feature pattern that contains information relating to the product chip
EP2637672B1 (en) 2010-11-12 2018-08-22 Gentium S.r.l. Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (gvhd).
KR102038357B1 (ko) 2012-06-22 2019-10-31 젠티엄 에스알엘 디파이브로타이드의 생물학적 활성 측정을 위한 유우글로불린에 기초한 방법
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
EP3661484A1 (en) 2017-08-03 2020-06-10 Jazz Pharmaceuticals Ireland Limited Formulations comprising a nucleic acid in a high concentration
WO2019200251A1 (en) 2018-04-12 2019-10-17 Jazz Pharmaceuticals, Inc. Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion
WO2020118165A1 (en) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Subcutaneous delivery of high concentration formulations
US20230190783A1 (en) 2020-02-28 2023-06-22 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1206341B (it) * 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
US4694134A (en) * 1985-05-28 1987-09-15 Ajax Magnethermic Corporation Apparatus for overheating edges of skelp for the production of compression welded pipe
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
US5223609A (en) * 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
US6699985B2 (en) * 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
IT1252174B (it) * 1991-12-09 1995-06-05 Crinos Industria Farmaco Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento
US5578716A (en) * 1993-12-01 1996-11-26 Mcgill University DNA methyltransferase antisense oligonucleotides
CA2259041A1 (en) * 1997-04-28 1998-11-05 Arsinur Burcoglu Method of treating hiv infection and related secondary infections thereof
AU8125098A (en) * 1997-05-30 1998-12-30 Mcgill University Dna methyltransferase genomic sequences and antisense oligonucleotides
DE19740384A1 (de) * 1997-09-08 1999-03-11 Max Delbrueck Centrum Antisense Oligodesoxynukleotide (ODN) gegen Proteinkinase C (PKC)-Isoformen, ihre Verwendung und pharmazeutische Zubereitungen dieser ODN
AU2002353783A1 (en) * 2001-09-24 2003-04-07 The Government Of The United States Of America As Represented By The Secretary Of The Department Of SUPPRESSORS OF CpG OLIGONUCLEOTIDES AND METHODS OF USE
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.

Also Published As

Publication number Publication date
AU2006222044A1 (en) 2006-09-14
EP1853277A1 (en) 2007-11-14
AU2006222045A1 (en) 2006-09-14
MX2007010754A (es) 2007-11-07
KR20070121001A (ko) 2007-12-26
WO2006094917A2 (en) 2006-09-14
WO2006094917A3 (en) 2006-12-14
AU2006222045B2 (en) 2011-10-20
CA2598072C (en) 2016-05-03
US20080194507A1 (en) 2008-08-14
CA2598072A1 (en) 2006-09-14
JP2008531647A (ja) 2008-08-14
KR20070120953A (ko) 2007-12-26
US20080194506A1 (en) 2008-08-14
CA2598613A1 (en) 2006-09-14
IL185181A0 (en) 2008-01-20
KR20070120954A (ko) 2007-12-26
WO2006094916A1 (en) 2006-09-14
WO2006094917A8 (en) 2008-01-31
IL185258A (en) 2010-12-30
JP5714203B2 (ja) 2015-05-07
IL185182A0 (en) 2008-01-20
EP1855697A2 (en) 2007-11-21
IL185258A0 (en) 2008-02-09
JP2008531646A (ja) 2008-08-14

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