MX2007006212A - Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular. - Google Patents

Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular.

Info

Publication number
MX2007006212A
MX2007006212A MX2007006212A MX2007006212A MX2007006212A MX 2007006212 A MX2007006212 A MX 2007006212A MX 2007006212 A MX2007006212 A MX 2007006212A MX 2007006212 A MX2007006212 A MX 2007006212A MX 2007006212 A MX2007006212 A MX 2007006212A
Authority
MX
Mexico
Prior art keywords
active principle
modified release
medicament
oral
release
Prior art date
Application number
MX2007006212A
Other languages
English (en)
Inventor
Remi Meyrueix
Florence Guimberteau
Catherine Castan
Gerard Soula
Original Assignee
Flamel Tech Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Tech Sa filed Critical Flamel Tech Sa
Publication of MX2007006212A publication Critical patent/MX2007006212A/es

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
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    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • AHUMAN NECESSITIES
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    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P3/06Antihyperlipidemics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/06Antianaemics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)

Abstract

El dominio de la invencion es aquel de medicamentos o composiciones farmaceuticas orales, mas particularmente del tipo de aquellas comprendiendo uno o varios principios activos. El objeto de la invencion es proporcionar un medicamento oral perfeccionado administrable en una o varias tomas cotidianas, para la liberacion modificada de principio activo (en particular un principio activo) permitiendo mejorar la eficacia profilactica y terapeutica de un tal medicamento. Este objeto se logra por la forma galenica oral multimicrocapsular segun la invencion en la cual la liberacion de PA se rige por un doble mecanismo de activacion de la liberacion: "activacion por tiempo" y "activacion por pH". Este medicamento comprende microcapsulas para la liberacion modificada de principio activo comprendiendo cada una un nucleo comprendiendo el principio activo y uno o varios agentes de hinchamiento y al menos un revestimiento permitiendo la liberacion modificada de principio activo.
MX2007006212A 2004-11-24 2005-11-02 Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular. MX2007006212A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0452748A FR2878159B1 (fr) 2004-11-24 2004-11-24 Medicament oral a liberation modifiee d'au moins un principe actif sous forme multimicrocapsulaire
PCT/FR2005/050922 WO2006056711A2 (fr) 2004-11-24 2005-11-02 Medicament oral a liberation modifiee d'au moins un principe actif sous forme multimicrocapsulaire

Publications (1)

Publication Number Publication Date
MX2007006212A true MX2007006212A (es) 2007-07-09

Family

ID=34953830

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006212A MX2007006212A (es) 2004-11-24 2005-11-02 Medicamento oral para liberacion modificada de al menos un principio activo bajo forma multimicrocapsular.

Country Status (18)

Country Link
US (1) US20080305160A1 (es)
EP (1) EP1827396B1 (es)
JP (1) JP5619342B2 (es)
KR (1) KR101391287B1 (es)
CN (1) CN101094658B (es)
AU (1) AU2005308639B2 (es)
BR (1) BRPI0518266B8 (es)
CA (1) CA2589137C (es)
ES (1) ES2588160T3 (es)
FR (1) FR2878159B1 (es)
HU (1) HUE029440T2 (es)
IL (1) IL183357A (es)
MX (1) MX2007006212A (es)
PT (1) PT1827396T (es)
SG (1) SG157406A1 (es)
TW (1) TW200630123A (es)
WO (1) WO2006056711A2 (es)
ZA (1) ZA200704163B (es)

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US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
CN108558690B (zh) * 2018-03-28 2021-04-20 浙江海正药业股份有限公司 环丝氨酸酯化物盐酸盐的晶型及其制备方法
JP2022522270A (ja) 2019-03-01 2022-04-15 フラメル アイルランド リミテッド 食事摂取状態における改善された薬物動態を有するガンマ-ヒドロキシ酪酸塩組成物
KR102546722B1 (ko) * 2020-04-21 2023-06-23 주식회사 바이오스탠다드 바이오코폴리머 마이크로 캡슐 포함 안정화 조성물, 그의 제조방법 및 이를 이용한 피부상태 개선용 화장료 조성물
GB202116589D0 (en) 2021-11-17 2021-12-29 Rb Health Us Llc Novel composition
GB202116588D0 (en) 2021-11-17 2021-12-29 Rb Health Us Llc Novel composition
GB202116590D0 (en) 2021-11-17 2021-12-29 Rb Health Us Llc Novel composition
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal

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ZA200704163B (en) 2008-08-27
AU2005308639B2 (en) 2011-05-26
KR20070098823A (ko) 2007-10-05
PT1827396T (pt) 2016-08-31
BRPI0518266A2 (pt) 2008-11-11
KR101391287B1 (ko) 2014-05-19
AU2005308639A1 (en) 2006-06-01
CN101094658B (zh) 2016-10-05
CA2589137A1 (fr) 2006-06-01
WO2006056711A3 (fr) 2006-08-31
SG157406A1 (en) 2009-12-29
HUE029440T2 (en) 2017-02-28
IL183357A0 (en) 2007-09-20
FR2878159A1 (fr) 2006-05-26
JP5619342B2 (ja) 2014-11-05
BRPI0518266B1 (pt) 2020-07-07
US20080305160A1 (en) 2008-12-11
EP1827396A2 (fr) 2007-09-05
ES2588160T3 (es) 2016-10-31
EP1827396B1 (fr) 2016-06-01
WO2006056711A2 (fr) 2006-06-01
IL183357A (en) 2014-12-31
FR2878159B1 (fr) 2008-10-17
CA2589137C (fr) 2014-08-26
TW200630123A (en) 2006-09-01
CN101094658A (zh) 2007-12-26
BRPI0518266B8 (pt) 2021-05-25
BRPI0518266A8 (pt) 2016-03-29
JP2008520633A (ja) 2008-06-19

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