MX2007005827A - S-mirtazapina para el tratamiento del sofoco. - Google Patents
S-mirtazapina para el tratamiento del sofoco.Info
- Publication number
- MX2007005827A MX2007005827A MX2007005827A MX2007005827A MX2007005827A MX 2007005827 A MX2007005827 A MX 2007005827A MX 2007005827 A MX2007005827 A MX 2007005827A MX 2007005827 A MX2007005827 A MX 2007005827A MX 2007005827 A MX2007005827 A MX 2007005827A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- mirtazapine
- week
- rats
- day
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 69
- RONZAEMNMFQXRA-MRXNPFEDSA-N esmirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)C[C@@H]2C2=CC=CC=C21 RONZAEMNMFQXRA-MRXNPFEDSA-N 0.000 title claims abstract description 33
- 206010060800 Hot flush Diseases 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims abstract description 12
- 208000033830 Hot Flashes Diseases 0.000 claims description 22
- 229960001785 mirtazapine Drugs 0.000 claims description 21
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 claims description 20
- 206010003497 Asphyxia Diseases 0.000 claims description 8
- 239000004480 active ingredient Substances 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 description 43
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- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 2
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- RPUBHMMISKEXSR-BTJKTKAUSA-N mirtazapine maleate Chemical compound OC(=O)\C=C/C(O)=O.C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RPUBHMMISKEXSR-BTJKTKAUSA-N 0.000 description 2
- 230000036651 mood Effects 0.000 description 2
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- 102000056834 5-HT2 Serotonin Receptors Human genes 0.000 description 1
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- 102000049773 5-HT2A Serotonin Receptor Human genes 0.000 description 1
- 102000006902 5-HT2C Serotonin Receptor Human genes 0.000 description 1
- 102100036321 5-hydroxytryptamine receptor 2A Human genes 0.000 description 1
- 101710138091 5-hydroxytryptamine receptor 2A Proteins 0.000 description 1
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 description 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 description 1
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- GJSURZIOUXUGAL-UHFFFAOYSA-N Clonidine Chemical compound ClC1=CC=CC(Cl)=C1NC1=NCCN1 GJSURZIOUXUGAL-UHFFFAOYSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
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- RONZAEMNMFQXRA-INIZCTEOSA-N LSM-5894 Chemical compound C1C2=CC=CN=C2N2CCN(C)C[C@H]2C2=CC=CC=C21 RONZAEMNMFQXRA-INIZCTEOSA-N 0.000 description 1
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- BLGXFZZNTVWLAY-CCZXDCJGSA-N Yohimbine Natural products C1=CC=C2C(CCN3C[C@@H]4CC[C@@H](O)[C@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-CCZXDCJGSA-N 0.000 description 1
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- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
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- BLGXFZZNTVWLAY-SCYLSFHTSA-N yohimbine Chemical compound C1=CC=C2C(CCN3C[C@@H]4CC[C@H](O)[C@@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04105778 | 2004-11-15 | ||
| PCT/EP2005/055947 WO2006051111A1 (en) | 2004-11-15 | 2005-11-14 | S-mirtazapine for the treatment of hot flush |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007005827A true MX2007005827A (es) | 2007-07-20 |
Family
ID=34929859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007005827A MX2007005827A (es) | 2004-11-15 | 2005-11-14 | S-mirtazapina para el tratamiento del sofoco. |
Country Status (30)
| Country | Link |
|---|---|
| US (4) | US20070265245A1 (https=) |
| EP (1) | EP1814555B1 (https=) |
| JP (1) | JP2008519810A (https=) |
| KR (1) | KR20070085470A (https=) |
| CN (2) | CN102772414A (https=) |
| AR (1) | AR053780A1 (https=) |
| AT (1) | ATE439843T1 (https=) |
| AU (1) | AU2005303778B2 (https=) |
| BR (1) | BRPI0517818A2 (https=) |
| CA (1) | CA2587283C (https=) |
| CY (1) | CY1110538T1 (https=) |
| DE (1) | DE602005016141D1 (https=) |
| DK (1) | DK1814555T3 (https=) |
| ES (1) | ES2329815T3 (https=) |
| HR (1) | HRP20090513T1 (https=) |
| IL (1) | IL182767A (https=) |
| MX (1) | MX2007005827A (https=) |
| MY (1) | MY144089A (https=) |
| NO (1) | NO20072285L (https=) |
| NZ (1) | NZ554858A (https=) |
| PE (1) | PE20061051A1 (https=) |
| PL (1) | PL1814555T3 (https=) |
| PT (1) | PT1814555E (https=) |
| RS (1) | RS51138B (https=) |
| RU (1) | RU2396957C2 (https=) |
| SI (1) | SI1814555T1 (https=) |
| TW (1) | TW200631584A (https=) |
| UA (1) | UA88655C2 (https=) |
| WO (1) | WO2006051111A1 (https=) |
| ZA (1) | ZA200703884B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1898919A2 (en) * | 2005-06-27 | 2008-03-19 | N.V. Organon | A method of treatment of hormone depletion induced vasomotor symptoms |
| US20070129611A1 (en) * | 2005-12-06 | 2007-06-07 | University Of North Texas Health Science Center At Fort Worth | System, Method and Apparatus for Assessing Menopausal or Post-Hysterectomy Symptoms |
| EP1993556A1 (en) * | 2006-03-06 | 2008-11-26 | N.V. Organon | An improved method of weaning from hormonal treatment of hormone depletion induced vasomotor symptoms |
| WO2008062021A1 (en) * | 2006-11-22 | 2008-05-29 | N.V. Organon | Vaginal delivery system for mirtazapine |
| US7645750B2 (en) * | 2006-12-13 | 2010-01-12 | Yung Shin Pharmaceutical Ind. Co., Ltd. | Method of treating symptoms of hormonal variations |
| JP2009018992A (ja) | 2007-07-10 | 2009-01-29 | Sumitomo Chemical Co Ltd | 光学活性ミルタザピンの製造方法 |
| US8420624B2 (en) | 2007-12-04 | 2013-04-16 | Yung Shin Pharm. Ind. Co., Ltd. | Methods for treating or preventing symptoms of hormonal variations |
| WO2016138357A1 (en) | 2015-02-27 | 2016-09-01 | Kindred Biosciences, Inc. | Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats |
| CA3064846A1 (en) * | 2017-05-25 | 2018-11-29 | Glytech, Llc | Combined therapy for nmdar antagonist-responsive neuropsychiatric disorders |
| US12564288B2 (en) | 2020-02-19 | 2026-03-03 | Ivan Ulinich | Universal device for heat treating food products |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| US4515792A (en) * | 1982-09-30 | 1985-05-07 | Ciba-Geigy Corporation | Tetracyclic heterocycles and antidepressant compositions thereof |
| JPH1187727A (ja) * | 1997-09-12 | 1999-03-30 | Mitsubishi Electric Corp | 半導体装置 |
| DE69913116T2 (de) * | 1998-04-02 | 2004-06-03 | Akzo Nobel N.V. | Orale flüssige lösung enthaltend das antidepressivum mirtazapine |
| RU2195951C1 (ru) * | 2001-08-20 | 2003-01-10 | Общество с ограниченной ответственностью "Лаборатория "Ирис" | Средство для лечения климактерических расстройств |
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