CN102772414A - 治疗潮红的s-米氮平 - Google Patents

治疗潮红的s-米氮平 Download PDF

Info

Publication number
CN102772414A
CN102772414A CN2012102639294A CN201210263929A CN102772414A CN 102772414 A CN102772414 A CN 102772414A CN 2012102639294 A CN2012102639294 A CN 2012102639294A CN 201210263929 A CN201210263929 A CN 201210263929A CN 102772414 A CN102772414 A CN 102772414A
Authority
CN
China
Prior art keywords
mirtazapine
treatment
rats
flushing
vasomotor symptoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012102639294A
Other languages
English (en)
Chinese (zh)
Inventor
B·W·M·M·B·彼得斯
A·E·P·阿丹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme BV
Original Assignee
MSD Oss BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34929859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102772414(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MSD Oss BV filed Critical MSD Oss BV
Publication of CN102772414A publication Critical patent/CN102772414A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN2012102639294A 2004-11-15 2005-11-14 治疗潮红的s-米氮平 Pending CN102772414A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04105778 2004-11-15
EP04105778.7 2004-11-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA200580038949XA Division CN101056641A (zh) 2004-11-15 2005-11-14 治疗潮红的s－米氮平

Publications (1)

Publication Number Publication Date
CN102772414A true CN102772414A (zh) 2012-11-14

Family

ID=34929859

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2012102639294A Pending CN102772414A (zh) 2004-11-15 2005-11-14 治疗潮红的s-米氮平
CNA200580038949XA Pending CN101056641A (zh) 2004-11-15 2005-11-14 治疗潮红的s－米氮平

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA200580038949XA Pending CN101056641A (zh) 2004-11-15 2005-11-14 治疗潮红的s－米氮平

Country Status (30)

Country Link
US (4) US20070265245A1 (https=)
EP (1) EP1814555B1 (https=)
JP (1) JP2008519810A (https=)
KR (1) KR20070085470A (https=)
CN (2) CN102772414A (https=)
AR (1) AR053780A1 (https=)
AT (1) ATE439843T1 (https=)
AU (1) AU2005303778B2 (https=)
BR (1) BRPI0517818A2 (https=)
CA (1) CA2587283C (https=)
CY (1) CY1110538T1 (https=)
DE (1) DE602005016141D1 (https=)
DK (1) DK1814555T3 (https=)
ES (1) ES2329815T3 (https=)
HR (1) HRP20090513T1 (https=)
IL (1) IL182767A (https=)
MX (1) MX2007005827A (https=)
MY (1) MY144089A (https=)
NO (1) NO20072285L (https=)
NZ (1) NZ554858A (https=)
PE (1) PE20061051A1 (https=)
PL (1) PL1814555T3 (https=)
PT (1) PT1814555E (https=)
RS (1) RS51138B (https=)
RU (1) RU2396957C2 (https=)
SI (1) SI1814555T1 (https=)
TW (1) TW200631584A (https=)
UA (1) UA88655C2 (https=)
WO (1) WO2006051111A1 (https=)
ZA (1) ZA200703884B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1898919A2 (en) * 2005-06-27 2008-03-19 N.V. Organon A method of treatment of hormone depletion induced vasomotor symptoms
US20070129611A1 (en) * 2005-12-06 2007-06-07 University Of North Texas Health Science Center At Fort Worth System, Method and Apparatus for Assessing Menopausal or Post-Hysterectomy Symptoms
EP1993556A1 (en) * 2006-03-06 2008-11-26 N.V. Organon An improved method of weaning from hormonal treatment of hormone depletion induced vasomotor symptoms
WO2008062021A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Vaginal delivery system for mirtazapine
US7645750B2 (en) * 2006-12-13 2010-01-12 Yung Shin Pharmaceutical Ind. Co., Ltd. Method of treating symptoms of hormonal variations
JP2009018992A (ja) 2007-07-10 2009-01-29 Sumitomo Chemical Co Ltd 光学活性ミルタザピンの製造方法
US8420624B2 (en) 2007-12-04 2013-04-16 Yung Shin Pharm. Ind. Co., Ltd. Methods for treating or preventing symptoms of hormonal variations
WO2016138357A1 (en) 2015-02-27 2016-09-01 Kindred Biosciences, Inc. Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats
CA3064846A1 (en) * 2017-05-25 2018-11-29 Glytech, Llc Combined therapy for nmdar antagonist-responsive neuropsychiatric disorders
US12564288B2 (en) 2020-02-19 2026-03-03 Ivan Ulinich Universal device for heat treating food products

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
US4515792A (en) * 1982-09-30 1985-05-07 Ciba-Geigy Corporation Tetracyclic heterocycles and antidepressant compositions thereof
JPH1187727A (ja) * 1997-09-12 1999-03-30 Mitsubishi Electric Corp 半導体装置
DE69913116T2 (de) * 1998-04-02 2004-06-03 Akzo Nobel N.V. Orale flüssige lösung enthaltend das antidepressivum mirtazapine
RU2195951C1 (ru) * 2001-08-20 2003-01-10 Общество с ограниченной ответственностью "Лаборатория "Ирис" Средство для лечения климактерических расстройств

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MALAGUENO,F.J. ET AL.: "New method for the chiral evaluation of mirtazapine in human plasma by liquid chromatography", 《JOURNAL OF CHROMATOGRAPHY B》 *
PEREZ,D.G. ET AL: "Pilot evaluation of mirtazapine for the treatment of hot flashes", 《THE JOURNAL OF SUPPORTIVE ONCOLOGY》 *

Also Published As

Publication number Publication date
DE602005016141D1 (de) 2009-10-01
TW200631584A (en) 2006-09-16
US20120302552A1 (en) 2012-11-29
WO2006051111A1 (en) 2006-05-18
ZA200703884B (en) 2009-07-29
JP2008519810A (ja) 2008-06-12
NZ554858A (en) 2009-10-30
ES2329815T3 (es) 2009-12-01
CN101056641A (zh) 2007-10-17
US20100267694A1 (en) 2010-10-21
PT1814555E (pt) 2009-09-30
CA2587283C (en) 2013-01-15
ATE439843T1 (de) 2009-09-15
KR20070085470A (ko) 2007-08-27
AU2005303778B2 (en) 2011-02-17
US20070265245A1 (en) 2007-11-15
UA88655C2 (ru) 2009-11-10
HRP20090513T1 (hr) 2009-10-31
DK1814555T3 (da) 2009-12-07
IL182767A0 (en) 2007-09-20
MX2007005827A (es) 2007-07-20
IL182767A (en) 2011-07-31
HK1104235A1 (en) 2008-01-11
CY1110538T1 (el) 2015-04-29
SI1814555T1 (sl) 2009-12-31
RS51138B (sr) 2010-10-31
NO20072285L (no) 2007-06-13
EP1814555A1 (en) 2007-08-08
PL1814555T3 (pl) 2010-01-29
CA2587283A1 (en) 2006-05-18
RU2396957C2 (ru) 2010-08-20
BRPI0517818A2 (pt) 2010-03-16
MY144089A (en) 2011-08-15
AU2005303778A1 (en) 2006-05-18
US20130225559A1 (en) 2013-08-29
EP1814555B1 (en) 2009-08-19
AR053780A1 (es) 2007-05-23
RU2007122391A (ru) 2008-12-20
PE20061051A1 (es) 2006-10-26

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20121114