MX2007004105A - Capsulas de lercanidipino. - Google Patents

Capsulas de lercanidipino.

Info

Publication number
MX2007004105A
MX2007004105A MX2007004105A MX2007004105A MX2007004105A MX 2007004105 A MX2007004105 A MX 2007004105A MX 2007004105 A MX2007004105 A MX 2007004105A MX 2007004105 A MX2007004105 A MX 2007004105A MX 2007004105 A MX2007004105 A MX 2007004105A
Authority
MX
Mexico
Prior art keywords
fatty acid
acid ester
lercanidipine
ester
mixture
Prior art date
Application number
MX2007004105A
Other languages
English (en)
Inventor
Amedeo Leonardi
Fabio Berlati
Lino Pontello
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of MX2007004105A publication Critical patent/MX2007004105A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Una composicion farmaceutica de liberacion modificada comprende lercanidipino disuelto en una sustancia cerea que comprende un ester polialcoholico de acidos grasos, encontrandose la disolucion contenida en una capsula farmaceuticamente aceptable. Preferentemente, el ester polialcoholico de acidos grasos es un ester del polietilenglicol, un ester del polipropilenglicol, un glicerido de acidos grasos o una mezcla de dos o mas de los mismos. Mas preferentemente, el ester polialcoholico de acidos grasos es una mezcla de mono-, di- y trigliceridos con mono- y diesteres del polietilenglicol. Se ha demostrado que la administracion oral a un paciente de las composiciones farmaceuticas de liberacion modificada produce una concentracion media de lercanidipino en plasma superior a los 0.5 ng/ml durante las 24 horas posteriores a la administracion.
MX2007004105A 2004-10-05 2005-10-05 Capsulas de lercanidipino. MX2007004105A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61591904P 2004-10-05 2004-10-05
US65679205P 2005-02-25 2005-02-25
PCT/EP2005/010813 WO2006037650A1 (en) 2004-10-05 2005-10-05 Lercanidipine capsules

Publications (1)

Publication Number Publication Date
MX2007004105A true MX2007004105A (es) 2007-06-15

Family

ID=35455723

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007004105A MX2007004105A (es) 2004-10-05 2005-10-05 Capsulas de lercanidipino.

Country Status (16)

Country Link
US (1) US20060073200A1 (es)
EP (1) EP1807059A1 (es)
JP (1) JP2008515839A (es)
KR (1) KR20070058632A (es)
AR (1) AR051742A1 (es)
AU (1) AU2005291354A1 (es)
BR (1) BRPI0516179A (es)
CA (1) CA2580525A1 (es)
EA (1) EA200700735A1 (es)
IL (1) IL181938A0 (es)
MX (1) MX2007004105A (es)
NO (1) NO20072332L (es)
PE (1) PE20060946A1 (es)
TW (1) TW200616681A (es)
UY (1) UY29150A1 (es)
WO (1) WO2006037650A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
AR052918A1 (es) * 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
WO2008040367A1 (en) * 2006-08-01 2008-04-10 Union Quimico-Farmaceutica S.A. Lercanidipine hydrobromide, a process for its preparation, crystalline forms and compositions thereof
US20080069878A1 (en) * 2006-08-31 2008-03-20 Gopi Venkatesh Drug Delivery Systems Comprising Solid Solutions of Weakly Basic Drugs
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
DE102010005124A1 (de) * 2010-01-19 2012-03-01 Stada Arzneimittel Ag Feste pharmazeutische Zusammensetzung umfassend Lercanidipin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
HU197201B (en) * 1985-10-01 1989-03-28 Sandoz Ag Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
US5696139A (en) * 1995-05-12 1997-12-09 Recordati S.A., Chemical And Pharmaceutical Company Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
US5912351A (en) * 1995-05-12 1999-06-15 Recordati, S.A. Chemical And Pharmaceutical Company Anhydrous 1,4-Dihydropyridines and salts thereof
DE69811233T2 (de) * 1997-10-27 2003-11-20 Merck Patent Gmbh Feste lösungen und dispersionen von eines schlecht wasserlöslichen wirkstoffes
US20030235595A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
US20030069285A1 (en) * 2001-08-06 2003-04-10 Recordati Ireland Limited Novel solvate and crystalline forms of lercanidipine hydrochloride
US6852737B2 (en) * 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride

Also Published As

Publication number Publication date
EA200700735A1 (ru) 2007-10-26
NO20072332L (no) 2007-05-04
IL181938A0 (en) 2007-07-04
AU2005291354A1 (en) 2006-04-13
UY29150A1 (es) 2005-11-30
WO2006037650A1 (en) 2006-04-13
AR051742A1 (es) 2007-02-07
US20060073200A1 (en) 2006-04-06
BRPI0516179A (pt) 2008-08-26
PE20060946A1 (es) 2006-10-02
JP2008515839A (ja) 2008-05-15
EP1807059A1 (en) 2007-07-18
TW200616681A (en) 2006-06-01
KR20070058632A (ko) 2007-06-08
CA2580525A1 (en) 2006-04-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal