MX2007003750A - Agentes de contraste enfocadores del receptor activador de plasminogeno de urocinasa (upar). - Google Patents

Agentes de contraste enfocadores del receptor activador de plasminogeno de urocinasa (upar).

Info

Publication number
MX2007003750A
MX2007003750A MX2007003750A MX2007003750A MX2007003750A MX 2007003750 A MX2007003750 A MX 2007003750A MX 2007003750 A MX2007003750 A MX 2007003750A MX 2007003750 A MX2007003750 A MX 2007003750A MX 2007003750 A MX2007003750 A MX 2007003750A
Authority
MX
Mexico
Prior art keywords
contrast agent
peptide
ser
alanine
trp
Prior art date
Application number
MX2007003750A
Other languages
English (en)
Spanish (es)
Inventor
Alan Cuthbertson
Bente E Arbo
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of MX2007003750A publication Critical patent/MX2007003750A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056Peptides, proteins, polyamino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2007003750A 2004-09-29 2005-09-28 Agentes de contraste enfocadores del receptor activador de plasminogeno de urocinasa (upar). MX2007003750A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20044139 2004-09-29
PCT/NO2005/000362 WO2006036071A2 (en) 2004-09-29 2005-09-28 Urokinase plasminogen activator receptor targeted contrast agent

Publications (1)

Publication Number Publication Date
MX2007003750A true MX2007003750A (es) 2007-11-07

Family

ID=35930012

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007003750A MX2007003750A (es) 2004-09-29 2005-09-28 Agentes de contraste enfocadores del receptor activador de plasminogeno de urocinasa (upar).

Country Status (11)

Country Link
US (1) US8568689B1 (https=)
EP (1) EP1796733A2 (https=)
JP (1) JP5122962B2 (https=)
KR (1) KR101248350B1 (https=)
CN (1) CN101065152A (https=)
AU (1) AU2005287934B2 (https=)
BR (1) BRPI0516168A (https=)
CA (1) CA2580464A1 (https=)
MX (1) MX2007003750A (https=)
RU (1) RU2394837C2 (https=)
WO (1) WO2006036071A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007044892A2 (en) * 2005-10-10 2007-04-19 American Diagnostica, Inc. Upar-binding molecule-drug conjugates and uses thereof
JP2010513476A (ja) * 2006-12-20 2010-04-30 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
EP2598175B1 (en) 2010-07-27 2020-05-20 Serac Healthcare Limited Radiopharmaceutical compositions
CA2905172C (en) * 2012-05-08 2021-07-20 Andreas Kjaer 177-lu labeled peptide for site-specific upar-targeting
CA3221851A1 (en) 2012-12-03 2014-06-12 Curasight A/S Positron emitting radionuclide labeled peptides for human upar pet imaging
CA2961095C (en) * 2014-09-17 2021-02-09 Rigshospitalet Upar targeting peptide for use in perioperative optical imaging of invasive cancer
US20210138090A1 (en) * 2014-09-17 2021-05-13 Fluoguide A/S uPAR targeting peptide for use in peroperative optical imaging of invasive cancer
AU2016271853B2 (en) * 2015-06-03 2020-10-22 Surgimab S.A.S. Fluorescent conjugates
EP3759121A1 (en) 2018-03-01 2021-01-06 Trigemina, Inc. Labeled oxytocin and method of manufacture and use
EP3999094B1 (en) * 2019-07-16 2026-02-25 Rigshospitalet A urokinase plasminogen activator receptor-targeting peptide
WO2021009219A1 (en) * 2019-07-16 2021-01-21 Fluoguide A/S A receptor-targeting conjugate with an effective pharmacokinetic profile
US20240009331A1 (en) * 2020-12-01 2024-01-11 Curasight A/S Urokinase plasminogen activator receptor targeted radiolabeled peptide conjugates
US20240066142A1 (en) * 2021-01-15 2024-02-29 Fluoguide A/S A upar (urokinase plasminogen activator receptor)-targeting conjugate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120765A (en) 1993-04-02 2000-09-19 Shiseido Co. Ltd. Urokinase plasminogen activator fragments
US6277818B1 (en) * 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5942492A (en) * 1996-11-12 1999-08-24 Angstrom Pharmaceuticals, Inc. Cyclic peptides that bind to urokinase-type plasminogen activator receptor
GB9705521D0 (en) * 1997-03-18 1997-05-07 Univ Sheffield The use of mononuclear phagocytes in the vivo imaging of hypoxic/ischaemic tissue
AR020101A1 (es) * 1998-07-01 2002-04-10 Cancerforskingsfonden Af 1989 Un antagonista peptido del receptor de uroquinasa humana, composicion farmaceutica que lo contiene, su uso para la manufactura de un medicamento y metodopara seleccionar un antagonista peptido adecuado.
US6896870B1 (en) * 1999-10-01 2005-05-24 Angstrom Pharmaceuticals, Inc. Diagnostic probes and therapeutics targeting uPA and uPAR
WO2001025410A2 (en) * 1999-10-01 2001-04-12 Angstrom Pharmaceuticals, Inc. DIAGNOSTIC PROBES AND THERAPEUTICS TARGETING uPA AND uPAR
RU2165266C1 (ru) * 2000-06-28 2001-04-20 Центральный научно-исследовательский рентгенорадиологический институт Способ получения [2-18f]-2-дезоксиглюкозы
JP2007526300A (ja) * 2004-03-04 2007-09-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 医薬化合物

Also Published As

Publication number Publication date
WO2006036071A3 (en) 2007-02-15
AU2005287934B2 (en) 2009-03-26
US8568689B1 (en) 2013-10-29
CN101065152A (zh) 2007-10-31
JP2008514588A (ja) 2008-05-08
EP1796733A2 (en) 2007-06-20
KR20070083604A (ko) 2007-08-24
RU2007111467A (ru) 2008-11-10
CA2580464A1 (en) 2006-04-06
WO2006036071A2 (en) 2006-04-06
RU2394837C2 (ru) 2010-07-20
JP5122962B2 (ja) 2013-01-16
BRPI0516168A (pt) 2008-08-26
AU2005287934A1 (en) 2006-04-06
KR101248350B1 (ko) 2013-04-01

Similar Documents

Publication Publication Date Title
De León-Rodríguez et al. The synthesis and chelation chemistry of DOTA− peptide conjugates
AU2003299957B2 (en) Improved gastrin releasing peptide compounds
JP7195665B2 (ja) 診断及び治療のための、改善された薬物動態及びコレシストキニン-2受容体(cck2r)への標的化
AU2005287934B2 (en) Urokinase plasminogen activator receptor targeted contrast agent
AU2018211539B2 (en) Compositions and methods for cancer imaging and radiotherapy
CA2512310C (en) Improved linkers for radiopharmaceutical compounds
JP4264263B2 (ja) コレシストキニンアゴニストおよびアンタゴニストの調製ならびにそれらの治療および診断の使用
JP5280682B2 (ja) ペプチド系化合物

Legal Events

Date Code Title Description
FG Grant or registration