BRPI0516168A - agente de formação de imagem upar, composição farmacêutica, e, método de geração de imagens de um corpo humano ou animal - Google Patents

agente de formação de imagem upar, composição farmacêutica, e, método de geração de imagens de um corpo humano ou animal

Info

Publication number
BRPI0516168A
BRPI0516168A BRPI0516168-1A BRPI0516168A BRPI0516168A BR PI0516168 A BRPI0516168 A BR PI0516168A BR PI0516168 A BRPI0516168 A BR PI0516168A BR PI0516168 A BRPI0516168 A BR PI0516168A
Authority
BR
Brazil
Prior art keywords
upar
human
pharmaceutical composition
animal body
imaging
Prior art date
Application number
BRPI0516168-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Alan Cuthbertson
Bente E Arbo
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of BRPI0516168A publication Critical patent/BRPI0516168A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0516168-1A 2004-09-29 2005-09-28 agente de formação de imagem upar, composição farmacêutica, e, método de geração de imagens de um corpo humano ou animal BRPI0516168A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20044139 2004-09-29
PCT/NO2005/000362 WO2006036071A2 (en) 2004-09-29 2005-09-28 Urokinase plasminogen activator receptor targeted contrast agent

Publications (1)

Publication Number Publication Date
BRPI0516168A true BRPI0516168A (pt) 2008-08-26

Family

ID=35930012

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516168-1A BRPI0516168A (pt) 2004-09-29 2005-09-28 agente de formação de imagem upar, composição farmacêutica, e, método de geração de imagens de um corpo humano ou animal

Country Status (11)

Country Link
US (1) US8568689B1 (https=)
EP (1) EP1796733A2 (https=)
JP (1) JP5122962B2 (https=)
KR (1) KR101248350B1 (https=)
CN (1) CN101065152A (https=)
AU (1) AU2005287934B2 (https=)
BR (1) BRPI0516168A (https=)
CA (1) CA2580464A1 (https=)
MX (1) MX2007003750A (https=)
RU (1) RU2394837C2 (https=)
WO (1) WO2006036071A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007044892A2 (en) * 2005-10-10 2007-04-19 American Diagnostica, Inc. Upar-binding molecule-drug conjugates and uses thereof
JP2010513476A (ja) * 2006-12-20 2010-04-30 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
EP2598175B1 (en) 2010-07-27 2020-05-20 Serac Healthcare Limited Radiopharmaceutical compositions
CA2905172C (en) * 2012-05-08 2021-07-20 Andreas Kjaer 177-lu labeled peptide for site-specific upar-targeting
CA3221851A1 (en) 2012-12-03 2014-06-12 Curasight A/S Positron emitting radionuclide labeled peptides for human upar pet imaging
CA2961095C (en) * 2014-09-17 2021-02-09 Rigshospitalet Upar targeting peptide for use in perioperative optical imaging of invasive cancer
US20210138090A1 (en) * 2014-09-17 2021-05-13 Fluoguide A/S uPAR targeting peptide for use in peroperative optical imaging of invasive cancer
AU2016271853B2 (en) * 2015-06-03 2020-10-22 Surgimab S.A.S. Fluorescent conjugates
EP3759121A1 (en) 2018-03-01 2021-01-06 Trigemina, Inc. Labeled oxytocin and method of manufacture and use
EP3999094B1 (en) * 2019-07-16 2026-02-25 Rigshospitalet A urokinase plasminogen activator receptor-targeting peptide
WO2021009219A1 (en) * 2019-07-16 2021-01-21 Fluoguide A/S A receptor-targeting conjugate with an effective pharmacokinetic profile
US20240009331A1 (en) * 2020-12-01 2024-01-11 Curasight A/S Urokinase plasminogen activator receptor targeted radiolabeled peptide conjugates
US20240066142A1 (en) * 2021-01-15 2024-02-29 Fluoguide A/S A upar (urokinase plasminogen activator receptor)-targeting conjugate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120765A (en) 1993-04-02 2000-09-19 Shiseido Co. Ltd. Urokinase plasminogen activator fragments
US6277818B1 (en) * 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
US5942492A (en) * 1996-11-12 1999-08-24 Angstrom Pharmaceuticals, Inc. Cyclic peptides that bind to urokinase-type plasminogen activator receptor
GB9705521D0 (en) * 1997-03-18 1997-05-07 Univ Sheffield The use of mononuclear phagocytes in the vivo imaging of hypoxic/ischaemic tissue
AR020101A1 (es) * 1998-07-01 2002-04-10 Cancerforskingsfonden Af 1989 Un antagonista peptido del receptor de uroquinasa humana, composicion farmaceutica que lo contiene, su uso para la manufactura de un medicamento y metodopara seleccionar un antagonista peptido adecuado.
US6896870B1 (en) * 1999-10-01 2005-05-24 Angstrom Pharmaceuticals, Inc. Diagnostic probes and therapeutics targeting uPA and uPAR
WO2001025410A2 (en) * 1999-10-01 2001-04-12 Angstrom Pharmaceuticals, Inc. DIAGNOSTIC PROBES AND THERAPEUTICS TARGETING uPA AND uPAR
RU2165266C1 (ru) * 2000-06-28 2001-04-20 Центральный научно-исследовательский рентгенорадиологический институт Способ получения [2-18f]-2-дезоксиглюкозы
JP2007526300A (ja) * 2004-03-04 2007-09-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 医薬化合物

Also Published As

Publication number Publication date
WO2006036071A3 (en) 2007-02-15
AU2005287934B2 (en) 2009-03-26
US8568689B1 (en) 2013-10-29
CN101065152A (zh) 2007-10-31
JP2008514588A (ja) 2008-05-08
MX2007003750A (es) 2007-11-07
EP1796733A2 (en) 2007-06-20
KR20070083604A (ko) 2007-08-24
RU2007111467A (ru) 2008-11-10
CA2580464A1 (en) 2006-04-06
WO2006036071A2 (en) 2006-04-06
RU2394837C2 (ru) 2010-07-20
JP5122962B2 (ja) 2013-01-16
AU2005287934A1 (en) 2006-04-06
KR101248350B1 (ko) 2013-04-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2325 DE 28-07-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.