MX2007000645A - Derivados de pirazolina, procedimiento para obtenerlos y uso de los mismos como agentes terapeuticos. - Google Patents

Derivados de pirazolina, procedimiento para obtenerlos y uso de los mismos como agentes terapeuticos.

Info

Publication number
MX2007000645A
MX2007000645A MX2007000645A MX2007000645A MX2007000645A MX 2007000645 A MX2007000645 A MX 2007000645A MX 2007000645 A MX2007000645 A MX 2007000645A MX 2007000645 A MX2007000645 A MX 2007000645A MX 2007000645 A MX2007000645 A MX 2007000645A
Authority
MX
Mexico
Prior art keywords
derivatives
obtaining
pyrazoline
procedure
therapeutic agents
Prior art date
Application number
MX2007000645A
Other languages
English (en)
Inventor
Rosa Cuberes Altisen
Jorg Holenz
Mario Colombo Pinol
Mercedes Port De Pol
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of MX2007000645A publication Critical patent/MX2007000645A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion se refiere a derivados de la formula general (I), y a sus sales farmaceuticamente aceptables, sus formas esteroisomericas, preferentemente sus formas enantiomericas o diastereomericas puras y sus formas racemicas, o una mezcla de las mismas en cualquier relacion de mezcla, y sus N-oxidos y los solvatos o hidratos correspondientes, a los procedimientos de obtencion de dichos derivados y a las composiciones farmaceuticas que los contienen. Dichos derivados son utiles como agentes antiinflamatorios y analgesicos. En donde R y R1 son diferentes entre si y se seleccionan de entre H y.
MX2007000645A 2004-07-16 2004-09-22 Derivados de pirazolina, procedimiento para obtenerlos y uso de los mismos como agentes terapeuticos. MX2007000645A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200401814A ES2257929B1 (es) 2004-07-16 2004-07-16 Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
PCT/IB2004/051822 WO2006011005A1 (en) 2004-07-16 2004-09-22 Derivatives of pyrazoline, procedure for obtaining them and use thereof as therapeutic agents

Publications (1)

Publication Number Publication Date
MX2007000645A true MX2007000645A (es) 2007-06-25

Family

ID=34958647

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007000645A MX2007000645A (es) 2004-07-16 2004-09-22 Derivados de pirazolina, procedimiento para obtenerlos y uso de los mismos como agentes terapeuticos.

Country Status (8)

Country Link
US (1) US7504519B2 (es)
EP (1) EP1773782A1 (es)
JP (1) JP2008506680A (es)
CN (1) CN101018771A (es)
CA (1) CA2578332A1 (es)
ES (1) ES2257929B1 (es)
MX (1) MX2007000645A (es)
WO (1) WO2006011005A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7998996B2 (en) * 2004-02-17 2011-08-16 Laboratorios Del Dr. Esteve S.A. Substituted pyrazoline compounds for reducing triglycerides in blood
NZ581309A (en) * 2007-05-25 2012-02-24 Vertex Pharma Ion channel modulators and methods of use
WO2009064938A1 (en) * 2007-11-16 2009-05-22 Abbott Laboratories Method of treating arthritis
JP6266804B2 (ja) * 2014-10-16 2018-01-24 堺ディスプレイプロダクト株式会社 表示装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
RU2169143C2 (ru) * 1995-05-25 2001-06-20 Джи. Ди. Сирл Энд Ко. Способ получения 3-галогеналкил-1н-пиразолов
GB9520584D0 (en) * 1995-10-09 1995-12-13 Fujisawa Pharmaceutical Co Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
EP0892791B1 (en) * 1996-04-12 2003-03-05 G.D. Searle & Co. N-[[4-(5-METHYL-3-PHENYLISOXAZOL-4-YL]PHENYL]SULFONYLPROPYLAMIDE and its SODIUMSALT AS PRODRUGS OF COX-2 INHIBITORS
ES2137138B1 (es) * 1998-05-29 2000-09-16 Esteve Labor Dr Derivados de pirazolinas, su preparacion y su aplicacion como medicamentos.
NZ516553A (en) 1999-06-16 2004-01-30 Univ Temple 1-(4-sulfamylaryl)-3-substituted-5-aryl-2-pyrazolines as inhibitors of cyclooxygenase-2 and its preparation method

Also Published As

Publication number Publication date
US7504519B2 (en) 2009-03-17
EP1773782A1 (en) 2007-04-18
ES2257929A1 (es) 2006-08-01
US20080021084A1 (en) 2008-01-24
JP2008506680A (ja) 2008-03-06
WO2006011005A1 (en) 2006-02-02
CN101018771A (zh) 2007-08-15
CA2578332A1 (en) 2006-02-02
ES2257929B1 (es) 2007-05-01

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