MX2007000413A - Antraciclina glicosidas liofilizadas estables. - Google Patents

Antraciclina glicosidas liofilizadas estables.

Info

Publication number
MX2007000413A
MX2007000413A MX2007000413A MX2007000413A MX2007000413A MX 2007000413 A MX2007000413 A MX 2007000413A MX 2007000413 A MX2007000413 A MX 2007000413A MX 2007000413 A MX2007000413 A MX 2007000413A MX 2007000413 A MX2007000413 A MX 2007000413A
Authority
MX
Mexico
Prior art keywords
stable lyophilized
hydrochloride
anthracycline glycosides
anthracycline glycoside
lyophilized anthracycline
Prior art date
Application number
MX2007000413A
Other languages
English (en)
Inventor
Roberto Arosio
Marco Villa
Simonetta Amati
Original Assignee
Sicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc filed Critical Sicor Inc
Publication of MX2007000413A publication Critical patent/MX2007000413A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

.
MX2007000413A 2005-05-11 2006-05-11 Antraciclina glicosidas liofilizadas estables. MX2007000413A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68013905P 2005-05-11 2005-05-11
PCT/US2006/018434 WO2006122309A2 (en) 2005-05-11 2006-05-11 Stable lyophilized anthracycline glycosides

Publications (1)

Publication Number Publication Date
MX2007000413A true MX2007000413A (es) 2007-06-15

Family

ID=37397341

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007000413A MX2007000413A (es) 2005-05-11 2006-05-11 Antraciclina glicosidas liofilizadas estables.

Country Status (9)

Country Link
US (1) US20070004653A1 (es)
EP (1) EP1814525A2 (es)
JP (1) JP2008513519A (es)
KR (1) KR20070088447A (es)
BR (1) BRPI0605832A2 (es)
CA (1) CA2606390A1 (es)
MX (1) MX2007000413A (es)
TW (1) TW200718426A (es)
WO (1) WO2006122309A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130686A2 (en) * 2005-06-02 2006-12-07 Schering Corporation Hcv protease inhibitors in combination with food
CA2611155A1 (en) * 2005-06-02 2006-12-07 Schering Corporation Pharmaceutical formulations and methods of treatment using the same
WO2009118754A2 (en) * 2008-03-28 2009-10-01 Astron Research Limited A process for preparing a stable lyophilized composition
DE102011103751A1 (de) * 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid
CN102614118B (zh) * 2012-03-15 2014-04-30 北京协和药厂 注射用盐酸表柔比星制剂的制备方法及制剂
CN103087124B (zh) * 2012-11-21 2016-01-13 浙江海正药业股份有限公司 一种制备阿霉素的方法
US20150087681A1 (en) * 2013-09-25 2015-03-26 Pranav Patel Bendamustine HCL Stable Lyophilized Formulations
CN104861014B (zh) * 2015-06-03 2017-09-29 道中道（菏泽）制药有限公司 一种盐酸表阿霉素结晶的制备方法
CN110483301A (zh) * 2018-06-11 2019-11-22 上海睿升化工科技有限公司 一种2-氧代戊烷-1,5-二甲酸二乙酯的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012284A (en) * 1962-11-16 1977-03-15 Societa' Farmaceutici Italia, S.p.A. Process of preparation of antibiotic F.I. 1762 derivatives
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
ES2198424T3 (es) * 1986-12-05 2004-02-01 Pharmacia Italia S.P.A. Soluciones inyectables listas para el empleo que contienen doxorrubicina.
FI883338A (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Vattenloesningar av doxorubicinhydroklorid.
JP2603480B2 (ja) * 1987-08-05 1997-04-23 住友製薬株式会社 安定化されたアンスラサイクリン系製剤
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
GB9926843D0 (en) * 1999-11-12 2000-01-12 Pharmacia & Upjohn Spa Lipid complex of alkycyclines
KR101059715B1 (ko) * 2002-11-29 2011-08-29 다이닛본 스미토모 세이야꾸 가부시끼가이샤 안정화된 안트라사이클린계 화합물의 동결 건조 제제
RU2341530C2 (ru) * 2003-07-02 2008-12-20 Солакс Корпорейшн Термостойкий кристаллический гидрохлорид эпирубицина и способ его получения

Also Published As

Publication number Publication date
CA2606390A1 (en) 2006-11-16
WO2006122309B1 (en) 2007-09-07
TW200718426A (en) 2007-05-16
US20070004653A1 (en) 2007-01-04
BRPI0605832A2 (pt) 2009-05-26
WO2006122309A2 (en) 2006-11-16
JP2008513519A (ja) 2008-05-01
WO2006122309A3 (en) 2007-06-28
KR20070088447A (ko) 2007-08-29
EP1814525A2 (en) 2007-08-08

Similar Documents

Publication Publication Date Title
MX2007000413A (es) Antraciclina glicosidas liofilizadas estables.
HK1071066A1 (en) Synergistic association of (-)- gossypol with docetaxel or paclitaxel for cancer treatment
MY165510A (en) Steviol glycoside isomers
IL186104A (en) Phosphoramidate History of Nucleoside Compounds
WO2007140191A3 (en) Glucose transport inhibitors and methods of use
UA100852C2 (ru) Композиции для лечения рака
UA99924C2 (en) Benzylbenzol derivatives and using thereof
MX2009009948A (es) Derivados de piridazinona utiles como inhibidores de glucano sintasa.
TW200734344A (en) Antibacterial agents
WO2007011962A3 (en) Treatment of cancer
WO2007059202A3 (en) Pyrazolyl urea derivatives useful in the treatment of cancer
TW200731974A (en) Transdermal system for verenicline
WO2007038868A3 (en) Novel enediyne compound and uses thereof
WO2007067559A3 (en) Antibacterial agents
IL190632A0 (en) Biphenyl derivatives and pharmaceutical compositions containing the same
WO2008083200A3 (en) Spiroheterocyclic glycosides and methods of use
PL2144515T3 (pl) Kompozycja słodzika o ulepszonym smaku
WO2006120563A3 (en) Antibacterial agents
WO2007120333A3 (en) Tetracyclic kinase inhibitors
WO2005085188A3 (en) Compounds and methods for anti-tumor therapy
WO2007120787A3 (en) Methods of treating, diagnosing or detecting cancers associated with liv-1 overexpression
TW200730530A (en) Lyophilized compositions of a triazolopyrimidine compound
EP2277884A8 (en) Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
WO2006081337A3 (en) Erastin analogues and their uses for killing cancer cells
WO2005000204A3 (en) Pancreatic cancer treatment

Legal Events

Date Code Title Description
FA Abandonment or withdrawal