MX173400B - Procedimiento para la preparacion de acido 6-hidroxinicotinico - Google Patents

Procedimiento para la preparacion de acido 6-hidroxinicotinico

Info

Publication number
MX173400B
MX173400B MX023758A MX2375890A MX173400B MX 173400 B MX173400 B MX 173400B MX 023758 A MX023758 A MX 023758A MX 2375890 A MX2375890 A MX 2375890A MX 173400 B MX173400 B MX 173400B
Authority
MX
Mexico
Prior art keywords
acid
microorganisms
nicotinic
nicotinic acid
procedure
Prior art date
Application number
MX023758A
Other languages
English (en)
Inventor
Frans Hoeks
Daniel Venetz
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of MX173400B publication Critical patent/MX173400B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/824—Achromobacter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/877—Pseudomonas putida

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención se refiere a procedimiento para la preparación de ácido 6-hidroxinicotínico por medio de la hidroxilación microbiológica de ácido nicotínico bajo condiciones aeróbicas, el cual procedimiento está caracterizado porque el ácido nicotínico o una sal soluble de ácido nicotínico o una solución que contenga ácido nicotínico, se agrega de manera continua o por porciones a un cultivo de partida de microorganismos, de tal forma que la concentración del ácido nicotínico durante la adición siempre es mayor que cero y en tanto que por lo menos, en lo esencial permanece debajo de esa concentración, arriba de la cual se produce una detención del crecimiento de los microorganismos, hasta que el ácido 6-hidroxinicotínico formado, detiene más el crecimiento, de modo que el aumento de los microorganismos y la formación del ácido 6-hidroxinicotínico se realizan en la misma etapa del procedimiento.
MX023758A 1989-12-20 1990-12-17 Procedimiento para la preparacion de acido 6-hidroxinicotinico MX173400B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH455589 1989-12-20

Publications (1)

Publication Number Publication Date
MX173400B true MX173400B (es) 1994-02-28

Family

ID=4278264

Family Applications (1)

Application Number Title Priority Date Filing Date
MX023758A MX173400B (es) 1989-12-20 1990-12-17 Procedimiento para la preparacion de acido 6-hidroxinicotinico

Country Status (11)

Country Link
US (1) US5151351A (es)
EP (1) EP0434035A1 (es)
JP (1) JPH04131088A (es)
KR (1) KR910012259A (es)
CA (1) CA2032658A1 (es)
CS (1) CS277658B6 (es)
FI (1) FI906101A (es)
HU (1) HU209917B (es)
IN (1) IN170700B (es)
MX (1) MX173400B (es)
RU (1) RU2015166C1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266482A (en) * 1990-11-08 1993-11-30 Lonza Ltd. Agrobacterium useful for the microbiological process for the production of hydroxylated pyrazine derivatives
EP0484908A3 (en) * 1990-11-08 1993-04-07 Lonza A.G. Microbiological process for the preparation of hydroxylated pyrazinederivatives
US5264362A (en) * 1991-03-18 1993-11-23 Lonza Ltd. Microbiological process for the production of 6-hydroxynicotinic acid
US5266469A (en) * 1991-03-18 1993-11-30 Lonza Ltd. Microbiological process for the production of 6-hydroxynicotinic acid
FI922125A (fi) * 1991-06-21 1992-12-22 Lonza Ag Mikrobidogiskt foerfarande foer framstaellning av 5-hydroxipyrazinkarboxylsyra
MX9204902A (es) * 1991-08-30 1993-05-01 Lonza Ag Procedimiento microbiologico para la preparacion de acido 6-hidroxipirazincarboxilico.
JP3153365B2 (ja) * 1991-12-05 2001-04-09 ロンザ リミテッド 芳香族複素環式ヒドロキシカルボン酸の微生物学的製造方法
JP3275353B2 (ja) * 1992-02-26 2002-04-15 三菱化学株式会社 ６−ヒドロキシ含窒素６員環化合物の製造方法
CZ282939B6 (cs) * 1992-03-04 1997-11-12 Lonza A.G. Mikrobiologický způsob hydroxylace dusíkatých heterocyklických karboxylových kyselin
US5763232A (en) * 1996-02-15 1998-06-09 Mitsubishi Chemical Corporation Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound
WO2005106006A2 (en) * 2004-05-05 2005-11-10 Jubilant Organosys Limited Biotransformation of nicotinic acid to 6-hydroxynicotinic acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038993A (en) * 1975-11-17 1977-08-02 Brown & Williamson Tobacco Corporation Process for reduction of nicotine content of tobacco by microbial treatment
CH644847A5 (en) * 1980-10-16 1984-08-31 Lonza Ag Process for the preparation of 2-hydroxypyridines from 2-pyridinecarboxylic acid N-oxides
CH658866A5 (de) * 1984-02-21 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
CH658867A5 (de) * 1984-02-22 1986-12-15 Lonza Ag Verfahren zur herstellung von 6-hydroxynikotinsaeure.
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.

Also Published As

Publication number Publication date
RU2015166C1 (ru) 1994-06-30
HU209917B (en) 1994-11-28
JPH04131088A (ja) 1992-05-01
CS277658B6 (en) 1993-03-17
CA2032658A1 (en) 1991-06-21
KR910012259A (ko) 1991-08-07
IN170700B (es) 1992-05-02
HUT61340A (en) 1992-12-28
HU908344D0 (en) 1991-07-29
US5151351A (en) 1992-09-29
EP0434035A1 (de) 1991-06-26
CS647590A3 (en) 1992-08-12
FI906101A0 (fi) 1990-12-12
FI906101A (fi) 1991-06-21

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