MX14431A - Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido - Google Patents

Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido

Info

Publication number
MX14431A
MX14431A MX1443189A MX1443189A MX14431A MX 14431 A MX14431 A MX 14431A MX 1443189 A MX1443189 A MX 1443189A MX 1443189 A MX1443189 A MX 1443189A MX 14431 A MX14431 A MX 14431A
Authority
MX
Mexico
Prior art keywords
indoles
aminoalkyl
carbonyl
prepare
procedure
Prior art date
Application number
MX1443189A
Other languages
English (en)
Inventor
Malcolm Rice Bell
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of MX14431A publication Critical patent/MX14431A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
MX1443189A 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido MX14431A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63793184A 1984-08-06 1984-08-06

Publications (1)

Publication Number Publication Date
MX14431A true MX14431A (es) 1993-08-01

Family

ID=24557949

Family Applications (4)

Application Number Title Priority Date Filing Date
MX8194A MX160612A (es) 1984-08-06 1985-08-06 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles
MX1443289A MX14432A (es) 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido
MX1442989A MX14429A (es) 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido.
MX1443189A MX14431A (es) 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido

Family Applications Before (3)

Application Number Title Priority Date Filing Date
MX8194A MX160612A (es) 1984-08-06 1985-08-06 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles
MX1443289A MX14432A (es) 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido
MX1442989A MX14429A (es) 1984-08-06 1989-01-04 Procedimiento para preparar 3-carbonil-1-aminoalquil-1h-indoles y producto obtenido.

Country Status (20)

Country Link
EP (1) EP0171037B1 (es)
JP (1) JPH0670010B2 (es)
KR (1) KR870000548B1 (es)
AR (1) AR244665A1 (es)
AT (1) ATE77371T1 (es)
AU (1) AU574817B2 (es)
DE (1) DE3586224T2 (es)
DK (1) DK170279B1 (es)
ES (5) ES8609246A1 (es)
FI (1) FI852973L (es)
GR (1) GR851937B (es)
IE (1) IE57863B1 (es)
IL (1) IL75966A (es)
MX (4) MX160612A (es)
MY (1) MY101186A (es)
NO (1) NO169067C (es)
NZ (3) NZ212953A (es)
PH (2) PH23498A (es)
PT (1) PT80919B (es)
ZA (1) ZA855923B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8623819D0 (en) * 1986-10-03 1986-11-05 Glaxo Group Ltd Heterocyclic compounds
US4840950A (en) * 1987-02-11 1989-06-20 Sterling Drug Inc. 4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
US5312829A (en) * 1990-05-21 1994-05-17 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
GB9011335D0 (en) * 1990-05-21 1990-07-11 Fujisawa Pharmaceutical Co Indolebutyric acid derivatives and process for preparation thereof
GB9204365D0 (en) * 1992-02-28 1992-04-08 Pfizer Ltd Indoles
TW270114B (es) * 1993-10-22 1996-02-11 Hoffmann La Roche
US5486525A (en) * 1993-12-16 1996-01-23 Abbott Laboratories Platelet activating factor antagonists: imidazopyridine indoles
EP1207153A1 (en) 1999-08-26 2002-05-22 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of indole derivatives or salts thereof
JP6493786B2 (ja) * 2015-01-06 2019-04-03 パナソニックIpマネジメント株式会社 免疫原、それを用いた抗体の製造方法、及び、そのモノクローナル抗体
JP6435505B2 (ja) * 2015-01-13 2018-12-12 パナソニックIpマネジメント株式会社 化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
US3217011A (en) * 1965-05-07 1965-11-09 Sterling Drug Inc 1-(indolyglyoxalyl)-piperidines
US3494920A (en) * 1967-12-18 1970-02-10 American Home Prod 1-di(lower)alkylamino(lower)alkyl-3-(2-substituted ethyl) indoles
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
GB1436771A (en) * 1973-02-16 1976-05-26 Labaz Indole derivatives and process for preparing the same
FR2354766A1 (fr) * 1976-06-17 1978-01-13 Labaz Derives n-aminoalkyles d'indole et procedes pour les preparer
ES8605232A1 (es) * 1984-02-07 1986-03-16 Pfizer Un procedimiento para la preparacion de compuestos de 2-o- xindol

Also Published As

Publication number Publication date
ES8609246A1 (es) 1986-07-16
ES552912A0 (es) 1987-10-16
PH25360A (en) 1991-05-13
ZA855923B (en) 1986-03-26
NO169067C (no) 1992-05-06
DE3586224T2 (de) 1993-01-28
IL75966A (en) 1989-08-15
DK354485D0 (da) 1985-08-05
JPS6147463A (ja) 1986-03-07
ES8800902A1 (es) 1987-12-01
DK170279B1 (da) 1995-07-24
NZ225466A (en) 1990-02-26
ES545894A0 (es) 1986-07-16
NZ212953A (en) 1990-02-26
FI852973L (fi) 1986-02-07
MX160612A (es) 1990-03-28
ES552910A0 (es) 1987-12-16
AU4576485A (en) 1986-02-13
FI852973A0 (fi) 1985-08-01
DE3586224D1 (de) 1992-07-23
EP0171037B1 (en) 1992-06-17
AR244665A1 (es) 1993-11-30
PT80919B (pt) 1987-09-30
ES8801203A1 (es) 1987-12-16
ES552909A0 (es) 1987-12-01
ES8800149A1 (es) 1987-10-16
EP0171037A2 (en) 1986-02-12
NO853066L (no) 1986-02-07
PH23498A (en) 1989-08-16
ES8800901A1 (es) 1987-12-01
KR870000548B1 (ko) 1987-03-18
NZ225467A (en) 1990-02-26
ATE77371T1 (de) 1992-07-15
JPH0670010B2 (ja) 1994-09-07
IE57863B1 (en) 1993-05-05
AU574817B2 (en) 1988-07-14
KR860001805A (ko) 1986-03-22
GR851937B (es) 1985-12-05
NO169067B (no) 1992-01-27
PT80919A (en) 1985-09-01
ES552911A0 (es) 1987-12-01
IE851930L (en) 1986-02-06
MX14432A (es) 1993-08-01
MX14429A (es) 1993-09-01
MY101186A (en) 1991-07-31
EP0171037A3 (en) 1987-08-26
IL75966A0 (en) 1985-12-31
DK354485A (da) 1986-02-07

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