ME03094B - Protutijela protiv kemokina pan-elr+ схс - Google Patents

Protutijela protiv kemokina pan-elr+ схс

Info

Publication number
ME03094B
ME03094B MEP-2018-173A MEP2018173A ME03094B ME 03094 B ME03094 B ME 03094B ME P2018173 A MEP2018173 A ME P2018173A ME 03094 B ME03094 B ME 03094B
Authority
ME
Montenegro
Prior art keywords
chemocins
elr
shs
antibodies against
against pan
Prior art date
Application number
MEP-2018-173A
Other languages
German (de)
English (en)
French (fr)
Inventor
Catherine Brautigam Beidler
Kristine Kay Kikly
Beth Ann Strifler
Derrick Ryan Witcher
Jeffrey Streetman Boyles
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ME03094B publication Critical patent/ME03094B/me

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
MEP-2018-173A 2013-03-15 2014-03-05 Protutijela protiv kemokina pan-elr+ схс ME03094B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361792800P 2013-03-15 2013-03-15
PCT/US2014/020605 WO2014149733A1 (en) 2013-03-15 2014-03-05 Pan-ELR+ CXC CHEMOKINE ANTIBODIES
EP14711899.6A EP2970447B1 (en) 2013-03-15 2014-03-05 Pan-elr+ cxc chemokine antibodies

Publications (1)

Publication Number Publication Date
ME03094B true ME03094B (me) 2019-01-20

Family

ID=50343858

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2018-173A ME03094B (me) 2013-03-15 2014-03-05 Protutijela protiv kemokina pan-elr+ схс

Country Status (35)

Country Link
EP (4) EP3348569B1 (me)
JP (1) JP6105146B2 (me)
KR (1) KR101745230B1 (me)
CN (2) CN109134652B (me)
AP (1) AP2015008731A0 (me)
AR (2) AR094960A1 (me)
AU (1) AU2014237898B2 (me)
CA (1) CA2901468C (me)
CL (1) CL2015002531A1 (me)
CY (1) CY1120459T1 (me)
DK (1) DK2970447T3 (me)
EA (1) EA029965B1 (me)
ES (3) ES2993153T3 (me)
HR (1) HRP20181047T1 (me)
HU (1) HUE038834T2 (me)
IL (2) IL241167B (me)
JO (1) JO3580B1 (me)
LT (1) LT2970447T (me)
MA (1) MA38413A1 (me)
ME (1) ME03094B (me)
MX (1) MX364831B (me)
MY (1) MY171213A (me)
NZ (1) NZ711704A (me)
PE (2) PE20151531A1 (me)
PH (1) PH12015502090B1 (me)
PL (1) PL2970447T3 (me)
PT (1) PT2970447T (me)
RS (1) RS57291B1 (me)
SG (1) SG11201507686TA (me)
SI (1) SI2970447T1 (me)
TN (1) TN2015000377A1 (me)
TR (1) TR201807613T4 (me)
TW (1) TWI612059B (me)
UA (1) UA116008C2 (me)
WO (1) WO2014149733A1 (me)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6416224B2 (ja) * 2013-05-17 2018-10-31 セントル ナショナル デ ラ ルシュルシュ サイエンティフィーク(シーエヌアールエス) 抗cxcl1抗体、抗cxcl7抗体および抗cxcl8抗体ならびにそれらの用途
US11485781B2 (en) 2017-08-17 2022-11-01 Massachusetts Institute Of Technology Multiple specificity binders of CXC chemokines
CN111770936A (zh) 2018-01-12 2020-10-13 百时美施贵宝公司 抗il-8抗体和抗pd-1抗体联合治疗用于治疗癌症
KR102049180B1 (ko) * 2018-04-02 2019-11-26 고려대학교 산학협력단 체세포에서 유도 만능 줄기세포로의 역분화 유도용 조성물 및 이를 이용한 역분화 유도방법
TWI737000B (zh) * 2018-10-22 2021-08-21 美商美國禮來大藥廠 用於治療化膿性汗腺炎之泛-elr+cxc趨化介素抗體
CA3154522A1 (en) 2019-10-15 2021-04-22 Christopher Carl Frye Recombinantly engineered, lipase/esterase-deficient mammalian cell lines
CN113087795B (zh) * 2019-12-23 2025-06-10 上海普铭生物科技有限公司 针对趋化因子cx3cl1的抗体及其应用
WO2021163031A1 (en) * 2020-02-12 2021-08-19 Eli Lilly And Company Crystallization of antibodies or antigen-binding fragments
TW202206457A (zh) 2020-04-24 2022-02-16 美商美國禮來大藥廠 用於治療呼吸疾病之泛elr+ cxc趨化因子抗體
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
WO2023192478A1 (en) 2022-04-01 2023-10-05 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040091503A1 (en) * 2002-08-20 2004-05-13 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
WO2007107002A1 (en) * 2006-03-22 2007-09-27 Osteopharm Inc. Markers for the diagnosis, monitoring and prognosis of osteoporosis and for assessing the risk for osteoporosis and for osteoporotic fractures
CL2008001071A1 (es) * 2007-04-17 2009-05-22 Smithkline Beecham Corp Metodo para obtener anticuerpo penta-especifico contra il-8/cxcl8, gro-alfa/cxcl1, gro-beta/cxcl2), gro-gama/cxcl3 y ena-78/cxcl5 humanas; anticuerpo penta-especifico; proceso de produccion del mismo; vector, hbridoma o celela que lo comprende; composicion farmceutica; uso para tratar copd, otras enfermedades.
HUE037489T2 (hu) * 2007-08-29 2018-08-28 Sanofi Sa Humanizált anti-CXCR5 antitestek, azok származékai és alkalmazásuk
GB0806812D0 (en) * 2008-04-15 2008-05-14 Univ Leuven Kath Citrullinated cytokines
KR20100133012A (ko) * 2008-05-14 2010-12-20 일라이 릴리 앤드 캄파니 항-cxcr4 항체
BR112012004387A2 (pt) * 2009-08-28 2015-09-08 Vlst Corp anticorpos anticinas que se l igam a múltiplas quimiocinas cc.
JP2011097867A (ja) * 2009-11-05 2011-05-19 Kurume Univ 脊柱靱帯骨化症のマーカーペプチド
US20120315267A1 (en) * 2010-02-09 2012-12-13 Glaxosmithkline Llc Novel uses
WO2013166099A1 (en) * 2012-05-01 2013-11-07 Glaxosmithkline Llc Novel antibodies

Also Published As

Publication number Publication date
CA2901468A1 (en) 2014-09-25
IL241167A0 (en) 2015-11-30
TN2015000377A1 (en) 2017-01-03
DK2970447T3 (en) 2018-06-18
ES2769123T3 (es) 2020-06-24
JP6105146B2 (ja) 2017-03-29
HUE038834T2 (hu) 2018-11-28
PL2970447T3 (pl) 2018-10-31
PH12015502090B1 (en) 2020-07-08
CN105143259A (zh) 2015-12-09
EP3348569A1 (en) 2018-07-18
EP2970447B1 (en) 2018-05-16
EP4467566A2 (en) 2024-11-27
JO3580B1 (ar) 2020-07-05
EA029965B1 (ru) 2018-06-29
EP3608336B1 (en) 2024-10-02
RS57291B1 (sr) 2018-08-31
KR101745230B1 (ko) 2017-06-08
AR125831A2 (es) 2023-08-16
MX2015013053A (es) 2016-05-18
PE20191480A1 (es) 2019-10-18
TWI612059B (zh) 2018-01-21
CN109134652B (zh) 2022-05-24
PE20151531A1 (es) 2015-10-28
SI2970447T1 (en) 2018-06-29
ES2675404T3 (es) 2018-07-11
UA116008C2 (uk) 2018-01-25
EP2970447A1 (en) 2016-01-20
EA201591514A1 (ru) 2016-03-31
AU2014237898B2 (en) 2016-05-05
AU2014237898A8 (en) 2015-08-27
TR201807613T4 (tr) 2018-06-21
KR20150119155A (ko) 2015-10-23
JP2016512026A (ja) 2016-04-25
IL269387A (en) 2019-11-28
SG11201507686TA (en) 2015-10-29
AU2014237898A1 (en) 2015-08-20
PH12015502090A1 (en) 2016-01-18
CA2901468C (en) 2018-02-20
IL241167B (en) 2019-10-31
TW201520226A (zh) 2015-06-01
HRP20181047T1 (hr) 2018-08-24
MX364831B (es) 2019-05-08
HK1212714A1 (en) 2016-06-17
PT2970447T (pt) 2018-08-07
IL269387B (en) 2021-05-31
AR094960A1 (es) 2015-09-09
BR112015020174A2 (pt) 2017-08-29
WO2014149733A1 (en) 2014-09-25
MY171213A (en) 2019-10-02
EP3348569B1 (en) 2019-11-27
NZ711704A (en) 2019-12-20
MA38413A1 (fr) 2017-10-31
LT2970447T (lt) 2018-07-25
CN105143259B (zh) 2018-09-21
CY1120459T1 (el) 2019-07-10
CL2015002531A1 (es) 2016-06-17
ES2993153T3 (en) 2024-12-23
AP2015008731A0 (en) 2015-09-30
CN109134652A (zh) 2019-01-04
EP3608336A1 (en) 2020-02-12
EP4467566A3 (en) 2025-04-23

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