ME00926B - Novi postupci za dobijanje diastereoselektivnog primarnog hiralnog amina na steroidu - Google Patents

Novi postupci za dobijanje diastereoselektivnog primarnog hiralnog amina na steroidu

Info

Publication number
ME00926B
ME00926B MEP-2009-225A MEP22509A ME00926B ME 00926 B ME00926 B ME 00926B ME P22509 A MEP22509 A ME P22509A ME 00926 B ME00926 B ME 00926B
Authority
ME
Montenegro
Prior art keywords
steroid
primary amine
novel method
chiral primary
diastereoselective
Prior art date
Application number
MEP-2009-225A
Other languages
English (en)
French (fr)
Inventor
Daniel Bernard
Joëlle Bousquet-Frances
Gérard Cazenave
Gilles Oddon
André Simonnet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ME00926B publication Critical patent/ME00926B/me

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Predmetni pronalazk se odnosi na diastereoselektivni postupak za dobijanje primarnog amina na steroidu, koji obuhvata redukciju oksima litijumom u amonijaku na  niskoj temperaturi u etar/alkohol smeši.
MEP-2009-225A 2006-12-13 2007-12-11 Novi postupci za dobijanje diastereoselektivnog primarnog hiralnog amina na steroidu ME00926B (me)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0610853A FR2910002B1 (fr) 2006-12-13 2006-12-13 Nouveau procede pour l'obtention diastereoselective d'une amine primaire chirale sur un steroide
PCT/FR2007/002035 WO2008090272A2 (fr) 2006-12-13 2007-12-11 Nouveau procede pour l'obtention diastereoselective d'une amine primaire chirale sur un steroïde

Publications (1)

Publication Number Publication Date
ME00926B true ME00926B (me) 2012-06-20

Family

ID=38331497

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2009-225A ME00926B (me) 2006-12-13 2007-12-11 Novi postupci za dobijanje diastereoselektivnog primarnog hiralnog amina na steroidu

Country Status (32)

Country Link
US (1) US20100069627A1 (me)
EP (1) EP2121724B1 (me)
JP (1) JP2010513252A (me)
KR (1) KR20090086593A (me)
CN (1) CN101558079B (me)
AR (1) AR064297A1 (me)
AT (1) ATE518877T1 (me)
AU (1) AU2007344926B2 (me)
BR (1) BRPI0720206A2 (me)
CA (1) CA2670655C (me)
CL (1) CL2007003621A1 (me)
CY (1) CY1113787T1 (me)
DK (1) DK2121724T3 (me)
EA (1) EA200970568A1 (me)
ES (1) ES2370537T3 (me)
FR (1) FR2910002B1 (me)
HK (1) HK1138287A1 (me)
HR (1) HRP20110797T1 (me)
MA (1) MA30980B1 (me)
ME (1) ME00926B (me)
MX (1) MX2009006309A (me)
MY (1) MY145902A (me)
NO (1) NO342093B1 (me)
NZ (1) NZ577439A (me)
PL (1) PL2121724T3 (me)
PT (1) PT2121724E (me)
RS (1) RS51993B (me)
SI (1) SI2121724T1 (me)
TW (1) TWI405769B (me)
UY (1) UY30792A1 (me)
WO (1) WO2008090272A2 (me)
ZA (1) ZA200903832B (me)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014200595A2 (en) 2013-03-15 2014-12-18 3D Systems, Inc. Direct writing for additive manufacturing systems

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3035066A (en) * 1961-07-06 1962-05-15 Syntex Sa Quaternary ammonium salts of 3beta, 20beta-diamino-allopregnanes
BE717065A (me) * 1967-06-26 1968-12-24
US3960961A (en) * 1970-08-31 1976-06-01 The Upjohn Company 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof
JPS4954358A (me) * 1972-09-30 1974-05-27
GB1581234A (en) * 1976-04-05 1980-12-10 Glaxo Operations Ltd 11a - amino - 3a - hydroxysteroids
US4197296A (en) * 1977-03-23 1980-04-08 Glaxo Group Limited Androstanes
ES494130A0 (es) * 1979-08-09 1981-10-01 Glaxo Group Ltd Un procedimiento para la preparacion de nuevos derivados de benzoxocina.
UA44257C2 (uk) * 1993-10-21 2002-02-15 Мерк Енд Ко, Інк 16-ЗАМІЩЕНІ ПОХІДНІ 4-АЗААНДРОСТАНУ, ЯК ІНГІБІТОРИ ІЗОФЕРМЕНТУ 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, СПОСІБ ІНГІБУВАННЯ 5-<font face="Symbol">a</font>-РЕДУКТАЗИ ТА ЇЇ ІЗОФЕРМЕНТУ, СПОСІБ ЛІКУВАННЯ, СПОСІБ ПРИПИНЕННЯ ТА ОБЕРНЕННЯ АНДРОГЕННОЇ АЛОПЕЦІЇ ТА СТИМУЛЮВАННЯ РОСТУ ВОЛОССЯ У ССАВЦІВ, СПОСІБ ІНГІБУВАННЯ БІОСИНТЕТИЧНОЇ КОНВЕРСІЇ ТЕСТОСТЕРОНУ В ДИГІДРОТЕСТОСТЕРОН У ССАВЦІВ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ
US6350738B1 (en) * 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics

Also Published As

Publication number Publication date
AR064297A1 (es) 2009-03-25
CY1113787T1 (el) 2016-07-27
KR20090086593A (ko) 2009-08-13
HK1138287A1 (en) 2010-08-20
BRPI0720206A2 (pt) 2013-12-31
SI2121724T1 (sl) 2011-12-30
HRP20110797T1 (hr) 2011-11-30
NO342093B1 (no) 2018-03-19
DK2121724T3 (da) 2011-11-21
CA2670655A1 (fr) 2008-07-31
JP2010513252A (ja) 2010-04-30
ES2370537T8 (es) 2012-02-13
TW200831526A (en) 2008-08-01
WO2008090272A2 (fr) 2008-07-31
EP2121724B1 (fr) 2011-08-03
ATE518877T1 (de) 2011-08-15
NO20092292L (no) 2009-09-09
FR2910002A1 (fr) 2008-06-20
US20100069627A1 (en) 2010-03-18
RS51993B (en) 2012-04-30
CN101558079B (zh) 2013-09-11
TWI405769B (zh) 2013-08-21
EP2121724A2 (fr) 2009-11-25
AU2007344926A1 (en) 2008-07-31
FR2910002B1 (fr) 2009-01-30
UY30792A1 (es) 2008-07-31
ES2370537T3 (es) 2011-12-19
PL2121724T3 (pl) 2011-12-30
AU2007344926B2 (en) 2013-03-07
CN101558079A (zh) 2009-10-14
WO2008090272A3 (fr) 2008-11-27
CA2670655C (fr) 2015-07-14
EA200970568A1 (ru) 2009-10-30
MY145902A (en) 2012-05-15
ZA200903832B (en) 2010-08-25
NZ577439A (en) 2012-02-24
CL2007003621A1 (es) 2009-03-27
MX2009006309A (es) 2009-08-19
PT2121724E (pt) 2011-11-21
MA30980B1 (fr) 2009-12-01

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