MD95C2 - Способ получения человеческого эритропоэтина - Google Patents

Способ получения человеческого эритропоэтина

Info

Publication number
MD95C2
MD95C2 MD94-0104A MD940104A MD95C2 MD 95 C2 MD95 C2 MD 95C2 MD 940104 A MD940104 A MD 940104A MD 95 C2 MD95 C2 MD 95C2
Authority
MD
Moldova
Prior art keywords
preparation
human
erythropoietine
recombinate
elimination
Prior art date
Application number
MD94-0104A
Other languages
English (en)
Romanian (ro)
Other versions
MD95B1 (ro
Inventor
Kenneth Jacobs
Edward Fritsch
Original Assignee
Genetics Institute, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24783958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD95(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US1985/002405 external-priority patent/WO1986003520A1/en
Priority claimed from SU864028136A external-priority patent/SU1672930A3/ru
Application filed by Genetics Institute, Inc. filed Critical Genetics Institute, Inc.
Publication of MD95B1 publication Critical patent/MD95B1/xx
Publication of MD95C2 publication Critical patent/MD95C2/ru

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретение относится к генетической инженерии и касается получения рекомбинантый плазмидных ДНК, содержащих гены эритропоэтина, которые обеспечивают высокие уровки экспрессиии указанных генов и получения in vitro активного человеческого эритропоэтина. Целью изобретения является повышение активности эритропоэтина. Способ состоит в том, что осуществляют получение геномного ДНК клона эритропоэтина человека гибридацией с зондами и его выделение, конструирование рекомбинантных плазмидных ДНК, кодирующих ЭПО человека с последующей трансформацией полученными ДНК штаммов клеток млекопитающих (например cos I), выделением и очисткой целового продукта.
MD94-0104A 1985-01-22 1994-02-09 Способ получения человеческого эритропоэтина MD95C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69325885A 1985-01-22 1985-01-22
PCT/US1985/002405 WO1986003520A1 (en) 1984-12-04 1985-12-03 Method for the production of erythropoietin
SU864028136A SU1672930A3 (ru) 1985-01-03 1986-08-01 Способ получени кДНК-клонов, кодирующих человеческий эритропоэтин
SU874203324A RU1801118C (ru) 1985-01-22 1987-09-09 Способ получени человеческого эритропоэтина

Publications (2)

Publication Number Publication Date
MD95B1 MD95B1 (ro) 1994-11-30
MD95C2 true MD95C2 (ru) 1995-03-31

Family

ID=24783958

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0104A MD95C2 (ru) 1985-01-22 1994-02-09 Способ получения человеческого эритропоэтина

Country Status (4)

Country Link
DD (1) DD279687A5 (ru)
MD (1) MD95C2 (ru)
RU (1) RU1801118C (ru)
UA (1) UA19039A (ru)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Brevet US nr. 4377513, Int. cl. A 61 K 37/24, 1983. *

Also Published As

Publication number Publication date
MD95B1 (ro) 1994-11-30
RU1801118C (ru) 1993-03-07
UA19039A (ru) 1997-12-25
DD279687A5 (de) 1990-06-13

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20051202