MD696Z - Metodă de tratament al complicaţiilor piciorului diabetic - Google Patents
Metodă de tratament al complicaţiilor piciorului diabetic Download PDFInfo
- Publication number
- MD696Z MD696Z MDS20130059A MDS20130059A MD696Z MD 696 Z MD696 Z MD 696Z MD S20130059 A MDS20130059 A MD S20130059A MD S20130059 A MDS20130059 A MD S20130059A MD 696 Z MD696 Z MD 696Z
- Authority
- MD
- Moldova
- Prior art keywords
- treatment
- wound
- diabetic foot
- separated
- suspension
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 25
- 208000008960 Diabetic foot Diseases 0.000 title claims abstract description 10
- 239000000725 suspension Substances 0.000 claims abstract description 11
- 210000004369 blood Anatomy 0.000 claims abstract description 8
- 239000008280 blood Substances 0.000 claims abstract description 8
- 210000005087 mononuclear cell Anatomy 0.000 claims abstract description 7
- 210000002027 skeletal muscle Anatomy 0.000 claims abstract description 6
- 210000004027 cell Anatomy 0.000 claims abstract description 3
- 230000008569 process Effects 0.000 abstract description 6
- 238000001356 surgical procedure Methods 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 2
- 206010052428 Wound Diseases 0.000 description 16
- 208000027418 Wounds and injury Diseases 0.000 description 16
- 239000001963 growth medium Substances 0.000 description 6
- 208000025865 Ulcer Diseases 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- 238000004113 cell culture Methods 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 230000001228 trophic effect Effects 0.000 description 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 239000012980 RPMI-1640 medium Substances 0.000 description 3
- PPTYJKAXVCCBDU-UHFFFAOYSA-N Rohypnol Chemical compound N=1CC(=O)N(C)C2=CC=C([N+]([O-])=O)C=C2C=1C1=CC=CC=C1F PPTYJKAXVCCBDU-UHFFFAOYSA-N 0.000 description 3
- 229960002897 heparin Drugs 0.000 description 3
- 229920000669 heparin Polymers 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000008439 repair process Effects 0.000 description 3
- 238000007920 subcutaneous administration Methods 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- LFHSNLRTGGKKRT-UHFFFAOYSA-N 3-iodopyran-2-one Chemical compound IC1=CC=COC1=O LFHSNLRTGGKKRT-UHFFFAOYSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- -1 TC 199 Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000123 anti-resoprtive effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 235000011148 calcium chloride Nutrition 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- DRFILBXQKYDTFW-JIWRMXRASA-L disodium;2-[[(2r)-2-[[(4s)-4-amino-4-carboxybutanoyl]amino]-3-[[(2r)-2-[[(4s)-4-amino-4-carboxybutanoyl]amino]-3-(carboxylatomethylamino)-3-oxopropyl]disulfanyl]propanoyl]amino]acetate Chemical compound [Na+].[Na+].OC(=O)[C@@H](N)CCC(=O)N[C@H](C(=O)NCC([O-])=O)CSSC[C@@H](C(=O)NCC([O-])=O)NC(=O)CC[C@H](N)C(O)=O DRFILBXQKYDTFW-JIWRMXRASA-L 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 108010068227 glutoxim Proteins 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000002956 necrotizing effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 210000004623 platelet-rich plasma Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130059A MD696Z (mo) | 2013-03-26 | 2013-03-26 | Metodă de tratament al complicaţiilor piciorului diabetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130059A MD696Z (mo) | 2013-03-26 | 2013-03-26 | Metodă de tratament al complicaţiilor piciorului diabetic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD696Y MD696Y (en) | 2013-11-30 |
| MD696Z true MD696Z (mo) | 2014-12-31 |
Family
ID=49724421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20130059A MD696Z (mo) | 2013-03-26 | 2013-03-26 | Metodă de tratament al complicaţiilor piciorului diabetic |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD696Z (mo) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD1179Z (ro) * | 2017-03-29 | 2018-03-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Metodă de tratament al ulcerelor trofice |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2144831C1 (ru) * | 1998-11-02 | 2000-01-27 | Дальневосточный государственный медицинский университет | Способ лечения синдрома диабетической стопы |
| RU2184551C2 (ru) * | 1999-12-31 | 2002-07-10 | Лопатин Сергей Вячеславович | Способ лечения деструктивных форм диабетической стопы |
| RU2228204C2 (ru) * | 2002-04-15 | 2004-05-10 | Научно-исследовательский институт клинической и экспериментальной лимфологии СО РАМН | Способ лечения трофических язв на фоне синдрома диабетической стопы |
| MD3076G2 (ro) * | 2004-11-09 | 2007-01-31 | Валериу РУДИК | Metodă de tratament al plăgilor necrotico-purulente la pacienţii cu picior diabetic |
| RU2322247C1 (ru) * | 2006-06-16 | 2008-04-20 | Нефедов Виктор Иванович | Способ лечения язвенных дефектов при синдроме диабетической стопы |
| RU2359624C1 (ru) * | 2008-03-06 | 2009-06-27 | Шамиль Арифулович Тенчурин | Способ лечения трофических язв при диабетической стопе |
-
2013
- 2013-03-26 MD MDS20130059A patent/MD696Z/mo not_active IP Right Cessation
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2144831C1 (ru) * | 1998-11-02 | 2000-01-27 | Дальневосточный государственный медицинский университет | Способ лечения синдрома диабетической стопы |
| RU2184551C2 (ru) * | 1999-12-31 | 2002-07-10 | Лопатин Сергей Вячеславович | Способ лечения деструктивных форм диабетической стопы |
| RU2228204C2 (ru) * | 2002-04-15 | 2004-05-10 | Научно-исследовательский институт клинической и экспериментальной лимфологии СО РАМН | Способ лечения трофических язв на фоне синдрома диабетической стопы |
| MD3076G2 (ro) * | 2004-11-09 | 2007-01-31 | Валериу РУДИК | Metodă de tratament al plăgilor necrotico-purulente la pacienţii cu picior diabetic |
| RU2322247C1 (ru) * | 2006-06-16 | 2008-04-20 | Нефедов Виктор Иванович | Способ лечения язвенных дефектов при синдроме диабетической стопы |
| RU2359624C1 (ru) * | 2008-03-06 | 2009-06-27 | Шамиль Арифулович Тенчурин | Способ лечения трофических язв при диабетической стопе |
Non-Patent Citations (2)
| Title |
|---|
| Ефимов А.С., Болгарская С.В., Таран Е.В. СИНДРОМ ДИАБЕТИЧЕСКОЙ СТОПЫ. СIМЕЙНА МЕДИЦИНА, № 1, 2008. с. 45-55 * |
| СУНЦОВ Ю. И., ДЕДОВ И. И., БОЛОТСКАЯ Л. Л. ЭКОНОМИЧЕСКИЙ ЭФФЕКТ ИСПОЛЬЗОВАНИЯ СОВРЕМЕННЫХ ТЕХНОЛОГИЙ В ЛЕЧЕНИИ САХАРНОГО ДИАБЕТА // Сахарный диабет. 2006. №2. С.60-62. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD696Y (en) | 2013-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
| MM4Y | Short-term patent definitely lapsed due to non-payment of fees |