MD4646B1 - Procedeu de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltă - Google Patents
Procedeu de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltăInfo
- Publication number
- MD4646B1 MD4646B1 MDA20180081A MD20180081A MD4646B1 MD 4646 B1 MD4646 B1 MD 4646B1 MD A20180081 A MDA20180081 A MD A20180081A MD 20180081 A MD20180081 A MD 20180081A MD 4646 B1 MD4646 B1 MD 4646B1
- Authority
- MD
- Moldova
- Prior art keywords
- larvae
- nutrient medium
- biomass
- biological activity
- galleria mellonella
- Prior art date
Links
- 239000002028 Biomass Substances 0.000 title abstract 4
- 241000255896 Galleria mellonella Species 0.000 title abstract 3
- 230000004071 biological effect Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 235000013312 flour Nutrition 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- RTIXKCRFFJGDFG-UHFFFAOYSA-N Chrysin Natural products C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 abstract 1
- 229940124091 Keratolytic Drugs 0.000 abstract 1
- FGUBFGWYEYFGRK-HNNXBMFYSA-N Pinocembrin Natural products Cc1cc(C)c2C(=O)C[C@H](Oc2c1)c3ccccc3 FGUBFGWYEYFGRK-HNNXBMFYSA-N 0.000 abstract 1
- 241000209140 Triticum Species 0.000 abstract 1
- 235000021307 Triticum Nutrition 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 229940041514 candida albicans extract Drugs 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 235000012907 honey Nutrition 0.000 abstract 1
- 230000001530 keratinolytic effect Effects 0.000 abstract 1
- SUYJZKRQHBQNCA-LSDHHAIUSA-N pinobanksin Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC=CC=C1 SUYJZKRQHBQNCA-LSDHHAIUSA-N 0.000 abstract 1
- SUYJZKRQHBQNCA-UHFFFAOYSA-N pinobanksin Natural products O1C2=CC(O)=CC(O)=C2C(=O)C(O)C1C1=CC=CC=C1 SUYJZKRQHBQNCA-UHFFFAOYSA-N 0.000 abstract 1
- URFCJEUYXNAHFI-ZDUSSCGKSA-N pinocembrin Chemical compound C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=CC=C1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 0.000 abstract 1
- 235000008476 powdered milk Nutrition 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 235000015099 wheat brans Nutrition 0.000 abstract 1
- 239000012138 yeast extract Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/90—Feeding-stuffs specially adapted for particular animals for insects, e.g. bees or silkworms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Husbandry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Biodiversity & Conservation Biology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
- Feed For Specific Animals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Invenţia se referă la biotehnologie, şi anume la obţinerea biomasei de larve de Galleria mellonella cu activitate cheratolitică, antioxidantă şi antiinflamatoare înaltă, care poate fi utilizată în calitate de materie primă pentru fabricarea preparatelor farmaceutice şi cosmetice.Procedeul de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltă constă în plasarea pupelor în recipiente cu mediu nutritiv, menţinerea lor până la eclozarea larvelor de prima vârstă, transferul larvelor în alte recipiente cu mediu nutritiv, cultivarea lor la temperatura de 27°C şi umiditatea de 75% timp de 19...21 de zile cu transferul larvelor de cel puţin 2 ori pe mediu nutritiv proaspăt şi colectarea larvelor, totodată mediul nutritiv conţine făină de grâu, făină de porumb, tărâţe de grâu, extract de drojdie, lapte praf, miere de albine, glicerol, pulbere de ceară, pinobanksin, pinocembrin şi apă.Rezultatul tehnic al invenţiei constă în sporirea cantităţii şi activităţii biologice a biomasei de larve obţinute.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20180081A MD4646C1 (ro) | 2018-09-19 | 2018-09-19 | Procedeu de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltă |
| EA202100067A EA202100067A1 (ru) | 2018-09-19 | 2019-07-23 | Способ получения биомассы личинок galleria mellonella с высокой биологической активностью |
| EP19862136.9A EP3854209A4 (en) | 2018-09-19 | 2019-07-23 | PROCESS FOR THE PRODUCTION OF BIOMASS FROM GALLERIA MELLONELLA LARVAE |
| PCT/MD2019/000005 WO2020060382A1 (ru) | 2018-09-19 | 2019-07-23 | Способ получения биомассы личинок galleria mellonella |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20180081A MD4646C1 (ro) | 2018-09-19 | 2018-09-19 | Procedeu de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltă |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4646B1 true MD4646B1 (ro) | 2019-09-30 |
| MD4646C1 MD4646C1 (ro) | 2020-04-30 |
Family
ID=68062709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20180081A MD4646C1 (ro) | 2018-09-19 | 2018-09-19 | Procedeu de obţinere a biomasei de larve de Galleria mellonella cu activitate biologică înaltă |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3854209A4 (ro) |
| EA (1) | EA202100067A1 (ro) |
| MD (1) | MD4646C1 (ro) |
| WO (1) | WO2020060382A1 (ro) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111493030B (zh) * | 2020-04-29 | 2022-10-14 | 金华市农业科学研究院 | 一种诱集大蜡螟幼虫的食物及其制备方法 |
| MD4852C1 (ro) * | 2022-02-07 | 2023-11-30 | Чеслав ЧУХРИЙ | Procedeu de obţinere a complexului entomologic cu activitate cheratolitică |
| CN114391516B (zh) * | 2022-02-18 | 2023-03-17 | 吉林省农业科学院 | 一种亚洲玉米螟田间人工接虫的介质及其制备方法和应用 |
| CN114916505A (zh) * | 2022-06-21 | 2022-08-19 | 新疆农业科学院土壤肥料与农业节水研究所(新疆维吾尔自治区新型肥料研究中心) | 一种大蜡螟生物降解农田残膜的种群延续研究方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2038086C1 (ru) * | 1991-03-26 | 1995-06-27 | Спиридонов Николай Алексеевич | Способ получения биологически активного продукта из личинок большой восковой моли |
| RU2210210C1 (ru) | 2001-11-21 | 2003-08-20 | Всероссийский научно-исследовательский институт биологической защиты растений | Способ разведения galleria mellonella l. |
| MD4198C1 (ro) * | 2011-08-26 | 2013-09-30 | Вячеслав ЧУХРИЙ | Complex de origine entomologică în propilenglicol cu acţiune cheratolitică, procedeu de obţinere a acestuia, produse farmaceutice şi cosmetice pe baza lui (variante) |
| CN107182948A (zh) * | 2017-06-12 | 2017-09-22 | 湖南工业大学 | 大蜡螟规模化培养新方法 |
-
2018
- 2018-09-19 MD MDA20180081A patent/MD4646C1/ro active IP Right Grant
-
2019
- 2019-07-23 EP EP19862136.9A patent/EP3854209A4/en active Pending
- 2019-07-23 EA EA202100067A patent/EA202100067A1/ru unknown
- 2019-07-23 WO PCT/MD2019/000005 patent/WO2020060382A1/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3854209A1 (en) | 2021-07-28 |
| MD4646C1 (ro) | 2020-04-30 |
| EP3854209A4 (en) | 2023-05-24 |
| WO2020060382A1 (ru) | 2020-03-26 |
| EA202100067A1 (ru) | 2021-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued |