MD3481370T2 - Compoziție farmaceutică care conţine benzidamină - Google Patents

Compoziție farmaceutică care conţine benzidamină

Info

Publication number
MD3481370T2
MD3481370T2 MDE20190569T MDE20190569T MD3481370T2 MD 3481370 T2 MD3481370 T2 MD 3481370T2 MD E20190569 T MDE20190569 T MD E20190569T MD E20190569 T MDE20190569 T MD E20190569T MD 3481370 T2 MD3481370 T2 MD 3481370T2
Authority
MD
Moldova
Prior art keywords
benzydamine
pharmaceutical composition
cream
gel
vaginitei
Prior art date
Application number
MDE20190569T
Other languages
English (en)
Inventor
Antonello Fazio
Serena Tongiani
Luca Donati
Claudio Milanese
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of MD3481370T2 publication Critical patent/MD3481370T2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Prezenta invenţie se referă la o cremă, cremă-gel sau compoziţie de gel farmaceutică care conţine benzidamină, având toleranţă şi eficacitate îmbunătăţite pentru prevenirea şi tratamentul stărilor inflamatorii şi / sau infecţioase în principal localizate în zona genitală, în special al vaginozei, vaginitei şi vulvo-vaginitei.
MDE20190569T 2016-07-08 2017-07-03 Compoziție farmaceutică care conţine benzidamină MD3481370T2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16178742 2016-07-08
PCT/EP2017/066438 WO2018007288A1 (en) 2016-07-08 2017-07-03 Pharmaceutical composition comprising benzydamine

Publications (1)

Publication Number Publication Date
MD3481370T2 true MD3481370T2 (ro) 2021-08-31

Family

ID=56408999

Family Applications (1)

Application Number Title Priority Date Filing Date
MDE20190569T MD3481370T2 (ro) 2016-07-08 2017-07-03 Compoziție farmaceutică care conţine benzidamină

Country Status (25)

Country Link
US (1) US20190224168A1 (ro)
EP (1) EP3481370B1 (ro)
JP (1) JP7060526B2 (ro)
KR (1) KR20190026686A (ro)
CN (1) CN109562058A (ro)
AR (1) AR109254A1 (ro)
AU (1) AU2017294402A1 (ro)
BR (1) BR112018077430A2 (ro)
CA (1) CA3025863A1 (ro)
CY (1) CY1124250T1 (ro)
DK (1) DK3481370T3 (ro)
EA (1) EA037435B1 (ro)
ES (1) ES2877133T3 (ro)
HR (1) HRP20210762T1 (ro)
HU (1) HUE054775T2 (ro)
IL (1) IL264083A (ro)
LT (1) LT3481370T (ro)
MD (1) MD3481370T2 (ro)
MX (1) MX2018015637A (ro)
PL (1) PL3481370T3 (ro)
PT (1) PT3481370T (ro)
RS (1) RS62022B1 (ro)
SG (1) SG11201900033UA (ro)
SI (1) SI3481370T1 (ro)
WO (1) WO2018007288A1 (ro)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE109978T1 (de) 1989-03-31 1994-09-15 Lepetit Spa Verwendung von purpuromycin zur behandlung von vaginalinfektionen.
CA2009402A1 (en) * 1990-02-06 1991-08-06 Attilio J. De Sanctis Use of benzydamine and salts thereof for relief of pain associated with herpes viral infections and laser vaporization of condylomata
GB9610359D0 (en) 1996-05-17 1996-07-24 Edko Trading Representation Pharmaceutical compositions
US6913759B2 (en) * 2003-03-11 2005-07-05 Curatek Pharmaceuticals Holding, Inc. Gel composition and method for treatment of vaginal infections
ITMI20031640A1 (it) * 2003-08-08 2005-02-09 Mipharm S P A Base per gel bioadesivi.
EP1698336A1 (en) * 2005-03-01 2006-09-06 Ferrer Internacional, S.A. Antifungal compositions comprising Sertaconazole and either Hydrocortisone or an antibacterial agent
ITBO20050388A1 (it) * 2005-06-06 2006-12-07 Alfa Wassermann Spa Formulazione mucoadesive utili in dispositivi medici in preparazioni farmaceutiche
US20070264309A1 (en) 2006-01-20 2007-11-15 Chollet Janet A Method Of Treating Atrophic Vaginitis
JP5193196B2 (ja) 2006-06-02 2013-05-08 ペア ツリー ウーマンズ ヘルス ケア 萎縮性膣炎の治療の方法
ITMI20071136A1 (it) 2007-06-04 2008-12-05 Velleja Res Srl Formulazioni topiche per la prevenzione e il trattamento degli stati infiammatori e/o infettivi dell'aera genitale
CN101219139A (zh) * 2007-12-24 2008-07-16 广西壮族自治区花红药业股份有限公司 盐酸苄达明栓剂及其制备方法
CN101214218A (zh) * 2007-12-26 2008-07-09 广西壮族自治区花红药业股份有限公司 盐酸苄达明凝胶剂及其制备方法
HUE028220T2 (en) 2009-07-08 2016-12-28 Acraf The use of benzidamine in the treatment of p40-dependent diseases
WO2013178749A1 (fr) * 2012-06-01 2013-12-05 Galderma Research & Development Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
US10806697B2 (en) * 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN107106690B (zh) 2015-01-13 2020-11-10 方济各安吉利克化学联合股份有限公司 用于治疗真菌病的药物组合物

Also Published As

Publication number Publication date
AR109254A1 (es) 2018-11-14
PT3481370T (pt) 2021-05-28
EA037435B1 (ru) 2021-03-26
KR20190026686A (ko) 2019-03-13
MX2018015637A (es) 2019-06-17
JP7060526B2 (ja) 2022-04-26
LT3481370T (lt) 2021-08-25
EP3481370B1 (en) 2021-03-24
AU2017294402A1 (en) 2018-12-20
HRP20210762T1 (hr) 2021-06-25
IL264083A (en) 2019-01-31
CA3025863A1 (en) 2018-01-11
BR112018077430A2 (pt) 2019-04-02
EA201990160A1 (ru) 2019-06-28
WO2018007288A1 (en) 2018-01-11
JP2019520370A (ja) 2019-07-18
ES2877133T3 (es) 2021-11-16
PL3481370T3 (pl) 2021-10-11
CN109562058A (zh) 2019-04-02
US20190224168A1 (en) 2019-07-25
SI3481370T1 (sl) 2021-08-31
RS62022B1 (sr) 2021-07-30
DK3481370T3 (da) 2021-06-07
HUE054775T2 (hu) 2021-09-28
EP3481370A1 (en) 2019-05-15
SG11201900033UA (en) 2019-02-27
CY1124250T1 (el) 2022-07-22

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