MD293Z - Utilizare a enotaninului hidrosolubil pentru tratamentul ulcerului gastric şi duodenal - Google Patents
Utilizare a enotaninului hidrosolubil pentru tratamentul ulcerului gastric şi duodenal Download PDFInfo
- Publication number
- MD293Z MD293Z MDS20100138A MDS20100138A MD293Z MD 293 Z MD293 Z MD 293Z MD S20100138 A MDS20100138 A MD S20100138A MD S20100138 A MDS20100138 A MD S20100138A MD 293 Z MD293 Z MD 293Z
- Authority
- MD
- Moldova
- Prior art keywords
- treatment
- water
- soluble
- oenotannin
- gastric
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 13
- 208000007107 Stomach Ulcer Diseases 0.000 title claims abstract description 5
- 208000000718 duodenal ulcer Diseases 0.000 title claims abstract description 5
- 230000002496 gastric effect Effects 0.000 title claims abstract description 5
- 201000005917 gastric ulcer Diseases 0.000 title abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000001590 oxidative effect Effects 0.000 claims description 4
- 208000008469 Peptic Ulcer Diseases 0.000 abstract description 6
- 231100000029 gastro-duodenal ulcer Toxicity 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 4
- 230000004071 biological effect Effects 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 description 14
- 231100000397 ulcer Toxicity 0.000 description 11
- 241000700159 Rattus Species 0.000 description 5
- 230000000767 anti-ulcer Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 230000001172 regenerating effect Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 241000219095 Vitis Species 0.000 description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 description 2
- 235000014787 Vitis vinifera Nutrition 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 229960000905 indomethacin Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 229920001864 tannin Polymers 0.000 description 2
- 239000001648 tannin Substances 0.000 description 2
- 235000018553 tannin Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010061164 Gastric mucosal lesion Diseases 0.000 description 1
- 206010017886 Gastroduodenal ulcer Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000016571 aggressive behavior Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 229920002770 condensed tannin Polymers 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229940038487 grape extract Drugs 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20100138A MD293Z (ro) | 2009-12-21 | 2009-12-21 | Utilizare a enotaninului hidrosolubil pentru tratamentul ulcerului gastric şi duodenal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20100138A MD293Z (ro) | 2009-12-21 | 2009-12-21 | Utilizare a enotaninului hidrosolubil pentru tratamentul ulcerului gastric şi duodenal |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| MD293Y MD293Y (en) | 2010-11-30 |
| MD293Z5 MD293Z5 (ru) | 2011-07-31 |
| MD293Z true MD293Z (ro) | 2011-07-31 |
Family
ID=45815235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20100138A MD293Z (ro) | 2009-12-21 | 2009-12-21 | Utilizare a enotaninului hidrosolubil pentru tratamentul ulcerului gastric şi duodenal |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD293Z (ru) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2074729C1 (ru) * | 1993-03-03 | 1997-03-10 | Сибирский государственный медицинский институт | Лекарственное средство для лечения язвенной болезни желудка и 12-перстной кишки "ахигран" |
| JPH10218769A (ja) * | 1997-02-06 | 1998-08-18 | Kikkoman Corp | 抗潰瘍剤 |
| MD869G2 (ru) * | 1997-03-24 | 1998-10-31 | Национальный Институт Винограда И Вина | Способ получения танинов и сопутствующих им продуктов из виноградных семян |
| MD1140C2 (ru) * | 1997-07-15 | 1999-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Средство с регенеративной и цитопротекторной активностью |
| MD2070G2 (ru) * | 2002-07-12 | 2003-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Применение нерафинированного масла из косточек винограда для лечения язв желудка и двенадцатиперстной кишки |
| MD3125G2 (ru) * | 2005-12-06 | 2007-05-31 | Институт Химии Академии Наук Молдовы | Способ получения водорастворимых энотаннинов |
| MD3228G2 (ru) * | 2006-03-07 | 2007-08-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Антибактериальное средство |
| KR100851962B1 (ko) * | 2006-11-13 | 2008-08-12 | 주식회사 케이씨에프코리아 | 포도씨 추출물 함유 항-헬리코박터 파이로리 조성물 |
-
2009
- 2009-12-21 MD MDS20100138A patent/MD293Z/ro not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MD293Z5 (ru) | 2011-07-31 |
| MD293Y (en) | 2010-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ND4Y | Validity of short term patent extended [from 6 to 10 years] |
Expiry date: 20191221 |
|
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
| MM4Y | Short-term patent definitely lapsed due to non-payment of fees |