MC1847A1 - Fragments d'interferons imnuns recombinants,homogenes et composition pharmaceutiques les contenant - Google Patents

Fragments d'interferons imnuns recombinants,homogenes et composition pharmaceutiques les contenant

Info

Publication number
MC1847A1
MC1847A1 MC871905A MC1905A MC1847A1 MC 1847 A1 MC1847 A1 MC 1847A1 MC 871905 A MC871905 A MC 871905A MC 1905 A MC1905 A MC 1905A MC 1847 A1 MC1847 A1 MC 1847A1
Authority
MC
Monaco
Prior art keywords
immun
interferons
recombinant
fragments
homogeneous
Prior art date
Application number
MC871905A
Other languages
English (en)
French (fr)
Inventor
Dobeli Heinz
Gentz Reiner
Hochuli Eric
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1847A1 publication Critical patent/MC1847A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MC871905A 1986-08-13 1987-08-10 Fragments d'interferons imnuns recombinants,homogenes et composition pharmaceutiques les contenant MC1847A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619725A GB8619725D0 (en) 1986-08-13 1986-08-13 Homogenous interferon fragments

Publications (1)

Publication Number Publication Date
MC1847A1 true MC1847A1 (fr) 1988-09-30

Family

ID=10602667

Family Applications (1)

Application Number Title Priority Date Filing Date
MC871905A MC1847A1 (fr) 1986-08-13 1987-08-10 Fragments d'interferons imnuns recombinants,homogenes et composition pharmaceutiques les contenant

Country Status (21)

Country Link
EP (1) EP0256424B1 (xx)
JP (1) JPS6349098A (xx)
KR (1) KR880002996A (xx)
AR (1) AR244808A1 (xx)
AT (1) ATE67783T1 (xx)
AU (1) AU607930B2 (xx)
DE (1) DE3773295D1 (xx)
DK (1) DK377787A (xx)
ES (1) ES2051714T3 (xx)
FI (1) FI873512A (xx)
GB (1) GB8619725D0 (xx)
GR (1) GR3003417T3 (xx)
HU (1) HU202920B (xx)
IE (1) IE60670B1 (xx)
IL (1) IL83474A0 (xx)
MC (1) MC1847A1 (xx)
NO (1) NO174631C (xx)
NZ (1) NZ221374A (xx)
PH (1) PH27432A (xx)
PT (1) PT85538B (xx)
ZA (1) ZA875819B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2969461B2 (ja) * 1988-07-23 1999-11-02 株式会社林原生物化学研究所 ヒトγ−インターフェロンとその製造方法並びに用途
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
WO1992004377A1 (en) * 1990-08-31 1992-03-19 Schering Corporation HUMAN INTERFERON-η4-134, FUNCTIONAL EQUIVALENTS THEREOF AND METHODS OF USING AND COMPOSITIONS EMPLOYING THESE MATERIALS
DE4036856C1 (xx) * 1990-11-19 1992-05-27 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
SK8292002A3 (en) 1999-11-12 2002-12-03 Maxygen Holdings Ltd A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof
CN1309423C (zh) 1999-11-12 2007-04-11 马克西根控股公司 干扰素γ偶联物
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
EP1539814A2 (en) 2002-07-03 2005-06-15 Maxygen Holdings Ltd. c/o Close Brothers (Cayman) Limited Full-length interferon gamma polypeptide variants
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
JPS60172999A (ja) * 1983-12-20 1985-09-06 Suntory Ltd 新規な塩基性ポリペプチドおよびその製造法
DK168016B1 (da) * 1983-12-26 1994-01-17 Kyowa Hakko Kogyo Kk Derivat af humant interferon-gamma-polypeptid
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
WO1985005618A1 (en) * 1984-06-06 1985-12-19 Takeda Chemical Industries, Ltd. Process for preparing interferon derivative
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof
JPS6124599A (ja) * 1984-07-11 1986-02-03 Kyowa Hakko Kogyo Co Ltd 新規ヒトインタ−フエロン−rポリペプチド誘導体
JPS6163696A (ja) * 1984-09-05 1986-04-01 Asahi Chem Ind Co Ltd 新しいペプチド
JPS61108397A (ja) * 1984-10-31 1986-05-27 Green Cross Corp:The インタ−フエロン−γ蛋白質の製造法
JPS62289600A (ja) * 1986-02-18 1987-12-16 Kanegafuchi Chem Ind Co Ltd インタ−フエロン−γ及びその製造方法

Also Published As

Publication number Publication date
NO873389D0 (no) 1987-08-12
ZA875819B (en) 1988-02-15
ES2051714T3 (es) 1994-07-01
GB8619725D0 (en) 1986-09-24
IL83474A0 (en) 1988-01-31
NO873389L (no) 1988-02-15
KR880002996A (ko) 1988-05-13
JPS6349098A (ja) 1988-03-01
PH27432A (en) 1993-06-21
DE3773295D1 (de) 1991-10-31
NO174631C (no) 1994-06-08
IE60670B1 (en) 1994-08-10
AR244808A1 (es) 1993-11-30
DK377787D0 (da) 1987-07-20
AU607930B2 (en) 1991-03-21
NO174631B (no) 1994-02-28
GR3003417T3 (en) 1993-02-17
FI873512A0 (fi) 1987-08-13
AU7668687A (en) 1988-05-19
HU202920B (en) 1991-04-29
EP0256424A1 (en) 1988-02-24
FI873512A (fi) 1988-02-14
EP0256424B1 (en) 1991-09-25
PT85538B (pt) 1990-06-29
HUT47148A (en) 1989-01-30
NZ221374A (en) 1990-07-26
DK377787A (da) 1988-02-14
PT85538A (en) 1987-09-01
ATE67783T1 (de) 1991-10-15
IE872160L (en) 1988-02-13

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