MC1727A1 - Derives de cholecalciferol - Google Patents

Derives de cholecalciferol

Info

Publication number
MC1727A1
MC1727A1 MC851813A MC1813A MC1727A1 MC 1727 A1 MC1727 A1 MC 1727A1 MC 851813 A MC851813 A MC 851813A MC 1813 A MC1813 A MC 1813A MC 1727 A1 MC1727 A1 MC 1727A1
Authority
MC
Monaco
Prior art keywords
alpha
dihydroxycholecalciferol
trifluoro
epimer
essentially free
Prior art date
Application number
MC851813A
Other languages
English (en)
French (fr)
Inventor
Enrico Baggiolini
Giacomo Pizzolato
Milan Uskokovic
Gary Truitt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1727A1 publication Critical patent/MC1727A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MC851813A 1984-12-19 1985-12-18 Derives de cholecalciferol MC1727A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68344284A 1984-12-19 1984-12-19

Publications (1)

Publication Number Publication Date
MC1727A1 true MC1727A1 (fr) 1986-12-15

Family

ID=24744070

Family Applications (1)

Application Number Title Priority Date Filing Date
MC851813A MC1727A1 (fr) 1984-12-19 1985-12-18 Derives de cholecalciferol

Country Status (14)

Country Link
EP (1) EP0186102B1 (de)
JP (1) JPH0684348B2 (de)
AT (1) ATE42948T1 (de)
AU (1) AU579212B2 (de)
DE (1) DE3570075D1 (de)
DK (1) DK159656C (de)
ES (1) ES8708210A1 (de)
FI (1) FI855017A (de)
GR (1) GR853047B (de)
HU (1) HU193358B (de)
MC (1) MC1727A1 (de)
NO (1) NO855119L (de)
PT (1) PT81708B (de)
ZA (1) ZA859138B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
JP4833908B2 (ja) * 2007-04-23 2011-12-07 東洋ゴム工業株式会社 防振ブッシュ
JP4716387B2 (ja) * 2008-09-02 2011-07-06 東洋ゴム工業株式会社 防振ブッシュ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
JPS56122348A (en) * 1980-03-03 1981-09-25 Teijin Ltd 25-hydroxy-26,26,26-trifluorovitamin d3, its oh-protected derivative, and its preparation
US4358406A (en) * 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same

Also Published As

Publication number Publication date
GR853047B (de) 1986-04-21
DK591285A (da) 1986-06-20
AU579212B2 (en) 1988-11-17
ZA859138B (en) 1986-08-27
FI855017A (fi) 1986-06-20
DK159656B (da) 1990-11-12
DE3570075D1 (en) 1989-06-15
JPH0684348B2 (ja) 1994-10-26
NO855119L (no) 1986-06-20
DK159656C (da) 1991-04-08
FI855017A0 (fi) 1985-12-17
EP0186102A3 (en) 1986-10-08
JPS61145139A (ja) 1986-07-02
EP0186102A2 (de) 1986-07-02
HUT39137A (en) 1986-08-28
PT81708B (en) 1987-10-15
EP0186102B1 (de) 1989-05-10
ES550072A0 (es) 1987-10-01
PT81708A (en) 1986-01-01
ATE42948T1 (de) 1989-05-15
DK591285D0 (da) 1985-12-18
ES8708210A1 (es) 1987-10-01
HU193358B (en) 1987-09-28
AU5133385A (en) 1986-06-26

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