MC1337A1 - Interferon de fibroblastes humains sous la forme d'une proteine homogene et sa preparation - Google Patents

Interferon de fibroblastes humains sous la forme d'une proteine homogene et sa preparation

Info

Publication number
MC1337A1
MC1337A1 MC801460A MC1460A MC1337A1 MC 1337 A1 MC1337 A1 MC 1337A1 MC 801460 A MC801460 A MC 801460A MC 1460 A MC1460 A MC 1460A MC 1337 A1 MC1337 A1 MC 1337A1
Authority
MC
Monaco
Prior art keywords
column
interferon
water
pyridine
formic acid
Prior art date
Application number
MC801460A
Other languages
English (en)
French (fr)
Inventor
S Pestka
H Friesen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1337A1 publication Critical patent/MC1337A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
MC801460A 1979-07-31 1980-07-29 Interferon de fibroblastes humains sous la forme d'une proteine homogene et sa preparation MC1337A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6237179A 1979-07-31 1979-07-31
US13063580A 1980-03-14 1980-03-14

Publications (1)

Publication Number Publication Date
MC1337A1 true MC1337A1 (fr) 1981-04-21

Family

ID=26742182

Family Applications (1)

Application Number Title Priority Date Filing Date
MC801460A MC1337A1 (fr) 1979-07-31 1980-07-29 Interferon de fibroblastes humains sous la forme d'une proteine homogene et sa preparation

Country Status (33)

Country Link
US (1) US5015730A (enExample)
JP (1) JPH02138226A (enExample)
AR (1) AR229931A1 (enExample)
AT (1) AT372387B (enExample)
AU (1) AU536274B2 (enExample)
CA (1) CA1146468A (enExample)
CH (1) CH648331A5 (enExample)
DE (1) DE3028919A1 (enExample)
DK (1) DK159825C (enExample)
DO (1) DOP1980002948A (enExample)
ES (1) ES493849A0 (enExample)
FI (1) FI70721C (enExample)
FR (1) FR2462167B1 (enExample)
GB (1) GB2055384B (enExample)
HK (1) HK40384A (enExample)
HU (1) HU185382B (enExample)
IE (1) IE50075B1 (enExample)
IL (1) IL60697A (enExample)
IT (1) IT1132269B (enExample)
KE (1) KE3364A (enExample)
LU (1) LU82673A1 (enExample)
MC (1) MC1337A1 (enExample)
MY (1) MY8500274A (enExample)
NL (1) NL8004361A (enExample)
NO (1) NO151158C (enExample)
NZ (1) NZ194495A (enExample)
PH (2) PH17738A (enExample)
PT (1) PT71625B (enExample)
RO (1) RO81474B (enExample)
SE (1) SE466290B (enExample)
YU (1) YU193480A (enExample)
ZA (1) ZA803943B (enExample)
ZW (1) ZW17980A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR74498B (enExample) 1980-04-03 1984-06-28 Biogen Inc
IT1139487B (it) * 1980-09-25 1986-09-24 Genentech Inc Produzione microbica di interferone di fibroblasti umani
ZA83768B (en) * 1982-03-01 1983-10-26 Hoffmann La Roche Homogeneous human immune interferon and process therefor
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US20030026779A1 (en) * 1999-10-15 2003-02-06 Liming Yu Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
US20050002902A1 (en) * 1995-12-28 2005-01-06 Liming Yu Hybrid with interferon-alpha and an immunoglobulin Fc for treatment of tumors and viral infections
MX2008002596A (es) 2005-08-26 2008-03-14 Ares Trading Sa Proceso para la preparacion de interferon beta glicosilado.
AU2006323925B2 (en) 2005-12-09 2012-08-02 Ares Trading S.A. Method for purifying FSH or a FSH mutant
CA2702448A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta

Also Published As

Publication number Publication date
US5015730A (en) 1991-05-14
DOP1980002948A (es) 1989-04-20
GB2055384A (en) 1981-03-04
SE466290B (sv) 1992-01-27
GB2055384B (en) 1983-08-10
NO151158B (no) 1984-11-12
DE3028919C2 (enExample) 1988-02-18
RO81474B (ro) 1983-04-30
DK328880A (da) 1981-02-01
PH18479A (en) 1985-07-18
ZA803943B (en) 1981-06-24
IE801589L (en) 1981-01-31
PH17738A (en) 1984-11-23
MY8500274A (en) 1985-12-31
JPH02138226A (ja) 1990-05-28
DK159825B (da) 1990-12-10
NZ194495A (en) 1984-07-31
FI70721C (fi) 1986-10-06
IL60697A (en) 1984-04-30
AU536274B2 (en) 1984-05-03
PT71625A (en) 1980-08-01
FI802400A7 (fi) 1981-02-01
NL8004361A (nl) 1981-02-03
PT71625B (en) 1981-12-17
DK159825C (da) 1991-04-29
AT372387B (de) 1983-09-26
IT8023801A0 (it) 1980-07-30
FR2462167A1 (fr) 1981-02-13
KE3364A (en) 1984-02-03
AU6091480A (en) 1981-02-05
LU82673A1 (fr) 1982-02-17
HK40384A (en) 1984-05-18
NO151158C (no) 1985-02-20
IT1132269B (it) 1986-07-02
FR2462167B1 (fr) 1985-07-05
RO81474A (ro) 1983-04-29
ES8200560A1 (es) 1981-11-16
ES493849A0 (es) 1981-11-16
FI70721B (fi) 1986-06-26
HU185382B (en) 1985-01-28
ATA395080A (de) 1983-02-15
ZW17980A1 (en) 1981-03-18
IE50075B1 (en) 1986-02-05
DE3028919A1 (de) 1981-02-19
CA1146468A (en) 1983-05-17
IL60697A0 (en) 1980-09-16
NO802297L (no) 1981-02-02
SE8005498L (sv) 1981-02-01
YU193480A (en) 1984-04-30
AR229931A1 (es) 1984-01-31
CH648331A5 (de) 1985-03-15

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