MC1213A1 - Derives imidazoliques utiles comme medicaments - Google Patents

Derives imidazoliques utiles comme medicaments

Info

Publication number
MC1213A1
MC1213A1 MC781323A MC1323A MC1213A1 MC 1213 A1 MC1213 A1 MC 1213A1 MC 781323 A MC781323 A MC 781323A MC 1323 A MC1323 A MC 1323A MC 1213 A1 MC1213 A1 MC 1213A1
Authority
MC
Monaco
Prior art keywords
medicinal products
derivatives useful
imidazolic
imidazolic derivatives
useful
Prior art date
Application number
MC781323A
Other languages
English (en)
Inventor
E Krebs
A Krasso
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1213A1 publication Critical patent/MC1213A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC781323A 1977-09-19 1978-08-31 Derives imidazoliques utiles comme medicaments MC1213A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU78140 1977-09-19
CH814978 1978-07-28

Publications (1)

Publication Number Publication Date
MC1213A1 true MC1213A1 (fr) 1979-05-18

Family

ID=25702876

Family Applications (1)

Application Number Title Priority Date Filing Date
MC781323A MC1213A1 (fr) 1977-09-19 1978-08-31 Derives imidazoliques utiles comme medicaments

Country Status (36)

Country Link
US (2) US4182766A (fr)
EP (1) EP0001279B1 (fr)
JP (1) JPS5459274A (fr)
AR (1) AR224350A1 (fr)
AT (1) AT368152B (fr)
AU (1) AU519711B2 (fr)
BG (1) BG28708A3 (fr)
BR (1) BR7806148A (fr)
CA (1) CA1106849A (fr)
DD (1) DD138210A5 (fr)
DE (2) DE2861237D1 (fr)
DK (1) DK406578A (fr)
EG (1) EG13530A (fr)
ES (1) ES473451A1 (fr)
FI (1) FI64365C (fr)
FR (1) FR2403340A1 (fr)
GB (1) GB2004281B (fr)
GR (1) GR73069B (fr)
HU (1) HU176111B (fr)
IE (1) IE47363B1 (fr)
IL (1) IL55557A (fr)
IN (1) IN148930B (fr)
IT (1) IT1098858B (fr)
MC (1) MC1213A1 (fr)
MT (1) MTP835B (fr)
NL (1) NL7809529A (fr)
NO (1) NO149962C (fr)
NZ (1) NZ188405A (fr)
OA (1) OA06054A (fr)
PH (1) PH16342A (fr)
PL (1) PL114494B1 (fr)
PT (1) PT68573A (fr)
RO (1) RO75258A (fr)
SE (1) SE7809792L (fr)
SU (1) SU793390A3 (fr)
YU (1) YU216778A (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4321372A (en) * 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4368201A (en) * 1981-07-20 1983-01-11 Usv Pharmaceutical Corporation Tetrahydronaphthoxazoles
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
HU193408B (en) * 1983-05-03 1987-10-28 Byk Gulden Lomberg Chem Fqb Process for production of new tree-cycle compounds
ZW4585A1 (en) * 1984-04-19 1985-11-20 Hoffmann La Roche Imidazole derivatives
DE3585252D1 (de) * 1984-07-06 1992-03-05 Fisons Plc Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen.
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
SE8404065D0 (sv) * 1984-08-10 1984-08-10 Haessle Ab Novel biologically active compounds
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
EP0204215B1 (fr) 1985-05-24 1993-08-11 G.D. Searle & Co. [(1H-benzimidazol-yl-2-sulfonyl)méthyl]-2-benzèneamines
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
DK337086A (da) * 1985-08-12 1987-02-13 Hoffmann La Roche Benzimidazolderivater
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
DE3701277A1 (de) * 1987-01-17 1988-07-28 Boehringer Mannheim Gmbh Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
US4931557A (en) * 1988-10-17 1990-06-05 Eli Lilly And Company Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof
SE8804629D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804628D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New compounds
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
WO1994001107A1 (fr) * 1992-07-08 1994-01-20 Monsanto Company Benzimidazoles utilises pour le traitement des ulceres de l'estomac chez le porc
WO1995029897A1 (fr) 1994-04-29 1995-11-09 G.D. Searle & Co. Procede d'utilisation d'inhibiteurs de (h+/k+)atpase comme agents antiviraux
ATE262332T1 (de) * 1995-09-21 2004-04-15 Pharma Pass Ii Llc Lansoprazolhaltige arzneizusammensetzung und herstellungsverfahren
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
KR100463031B1 (ko) * 1997-05-26 2005-04-06 동아제약주식회사 5-메톡시-2-[3,5-디메틸-4-메톡시피리딜메틸)설피닐]-1h-벤즈이미다졸의신규제조방법
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
MXPA04007169A (es) * 2002-01-25 2004-10-29 Santarus Inc Suministro transmucosal de inhibidores de bomba de protones.
CA2517005A1 (fr) * 2003-02-20 2004-09-02 Santarus, Inc. Liberation immediate d'un complexe antacide d'omeprazole presentant une nouvelle formulation pour une elimination rapide et prolongee d'acide gastrique
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005007115A2 (fr) * 2003-07-18 2005-01-27 Santarus, Inc. Formulations pharmaceutiques utilisees pour inhiber une secretion acide et procede de fabrication associe
AR045061A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulacion farmaceutica y metodo para tratar trastornos gastrointestinales causados por acido
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20060024362A1 (en) * 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
CA2665226C (fr) 2006-10-05 2014-05-13 Santarus, Inc. Nouvelles formulations pour une liberation immediate d'inhibiteurs de pompe a protons et procedes d'utilisation de ces formulations
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2486910A3 (fr) 2006-10-27 2012-08-22 The Curators Of The University Of Missouri Appareil comprenant plusieurs chambres et une tête de distribution
WO2024075017A1 (fr) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition de calcification de valve aortique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985661A (en) * 1956-02-06 1961-05-23 American Cyanamid Co Preparation of 2(omicron-aminophenyl)-benzimidazole
GB1234058A (fr) * 1968-10-21 1971-06-03
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen

Also Published As

Publication number Publication date
DK406578A (da) 1979-03-20
HU176111B (en) 1980-12-28
AR224350A1 (es) 1981-11-30
FI782847A (fi) 1979-03-20
DE2861237D1 (en) 1981-12-10
CA1106849A (fr) 1981-08-11
ES473451A1 (es) 1979-05-01
PL209693A1 (pl) 1979-06-04
FI64365B (fi) 1983-07-29
EP0001279B1 (fr) 1981-09-30
NO149962C (no) 1984-07-25
NL7809529A (nl) 1979-03-21
GR73069B (fr) 1984-01-30
ATA673378A (de) 1982-01-15
IL55557A0 (en) 1978-12-17
YU216778A (en) 1983-01-21
US4182766A (en) 1980-01-08
AU3981778A (en) 1980-03-20
IN148930B (fr) 1981-07-25
IT1098858B (it) 1985-09-18
BG28708A3 (en) 1980-06-16
SE7809792L (sv) 1979-03-20
EG13530A (en) 1981-12-31
IT7827861A0 (it) 1978-09-19
IE781878L (en) 1979-03-19
RO75258A (fr) 1980-11-30
NZ188405A (en) 1981-03-16
PH16342A (en) 1983-09-05
GB2004281B (en) 1982-03-10
FR2403340B1 (fr) 1981-02-13
MTP835B (en) 1979-11-14
DE2840591A1 (de) 1979-03-29
FR2403340A1 (fr) 1979-04-13
US4248880A (en) 1981-02-03
SU793390A3 (ru) 1980-12-30
NO783155L (no) 1979-03-20
OA06054A (fr) 1981-06-30
IE47363B1 (en) 1984-03-07
GB2004281A (en) 1979-03-28
PL114494B1 (en) 1981-01-31
PT68573A (fr) 1978-10-01
IL55557A (en) 1982-02-28
AT368152B (de) 1982-09-27
DD138210A5 (de) 1979-10-17
FI64365C (fi) 1983-11-10
JPS5459274A (en) 1979-05-12
BR7806148A (pt) 1979-04-17
AU519711B2 (en) 1981-12-17
NO149962B (no) 1984-04-16
EP0001279A1 (fr) 1979-04-04

Similar Documents

Publication Publication Date Title
MC1213A1 (fr) Derives imidazoliques utiles comme medicaments
BE824359A (fr) Derives biphenyles utiles comme medicaments
PT70503A (fr) Derives de la phenil-1 (piperidyl-4)-3-propanone-1 utilisables comme medicaments
FR2352808A1 (fr) Acides 12-azaprostanoiques utiles comme medicaments
NO820290L (no) Mellomprodukter for fremstilling av terapeutisk aktive antrakinon-derivater.
BE865624A (fr) Interphenylene 8-aza-9-dioxathia-11,12-secoprostaglandines utiles comme medicaments
BE850556A (fr) Nouveaux n-aryl-diazacycles oxygenes utiles comme medicaments
BE866057A (fr) Derives de l'aniline utilisables comme medicament
SE7809373L (sv) Farmaceutiskt anvendbara 5-hydroxi-1h-imidazol-4-karboxamidderivat
FI781330A (fi) Foerbaettrad begraensare foer medelstroemmaengden av en straole
FI772319A (fi) Anordning foer orientering av med bindemedel foersedda lignocellulosahaltiga delar
FR2350099A1 (fr) 2-imino-thiazolidines et thiazolines utiles comme medicaments
BE868991R (fr) Nouveaux phenylazacycloalcanes utiles comme medicaments
FR2321294A1 (fr) Derives d'acides 7b-amino-3-cephem-3-carbonylmethyl-4-carboxyliques utiles comme medicaments
BE825135A (fr) Derives de la benzofurannone utilisables comme medicaments
NO833255L (no) Mellomprodukter for fremstilling av guanidinderivater
FR2316939A1 (fr) Derives de 2-benzopyranone et leur application comme medicaments
NO811914L (no) Mellomprodukter for fremstilling av antibakterielt aktive oleandomycin-derivater
BE861514A (fr) Derives de la piperazine utilisables comme medicaments
FR2332017A1 (fr) Antibiotiques de type thienamycine utiles comme medicaments
BE865406A (fr) Derives 3'-oxygenes des 4'-desoxy vlb "a" et "b" et des derives 1-formyles apparentes, et leur utilisation comme medicaments
BE862197R (fr) Derives biphenyles utiles comme medicaments
BE868684A (fr) Derives de 4-homoisotwistanes et leur utilisation comme medicaments
FR2340944A1 (fr) Derives de 2-aminomethyl-5-phenyloxazole utilisables comme medicaments anti-inflammatoires et analgesiques
BE864998A (fr) Derives de s,s'-decamethylene-1, 10-mercaptan utiles comme medicaments normolipidemiants

Legal Events

Date Code Title Description
YP Annual fee paid